Calcium in PDB 4hzv: The Crystal Structure of Influenza A Neuraminidase N3

The structure of The Crystal Structure of Influenza A Neuraminidase N3, PDB code: 4hzv was solved by Q.Li, J.Qi, C.J.Vavricka, G.F.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.57 / 1.80
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	106.144, 106.144, 64.003, 90.00, 90.00, 90.00
R / Rfree (%)	14.7 / 18.5

The binding sites of Calcium atom in the The Crystal Structure of Influenza A Neuraminidase N3 (pdb code 4hzv). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the The Crystal Structure of Influenza A Neuraminidase N3, PDB code: 4hzv:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the The Crystal Structure of Influenza A Neuraminidase N3


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of The Crystal Structure of Influenza A Neuraminidase N3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca507 b:31.6 occ:1.00 O A:ASP293 2.4 24.9 1.0 O A:GLY345 2.4 28.9 1.0 OD2 A:ASP324 2.5 24.8 1.0 O A:PRO347 2.5 32.0 1.0 O A:HOH640 2.6 28.9 1.0 O A:GLY297 2.6 26.1 1.0 C A:GLY345 3.5 32.1 1.0 CG A:ASP324 3.5 26.6 1.0 C A:ASP293 3.6 25.2 1.0 C A:GLY297 3.6 29.2 1.0 C A:PRO347 3.7 35.5 1.0 CA A:GLY348 4.0 25.2 1.0 O A:HOH642 4.1 22.9 1.0 CA A:ASN294 4.1 27.4 1.0 CB A:ASP324 4.2 24.3 1.0 N A:GLY348 4.3 31.0 1.0 N A:GLY346 4.3 36.5 1.0 N A:ASN294 4.3 23.1 1.0 OD1 A:ASP324 4.3 23.6 1.0 CA A:GLY346 4.3 31.6 1.0 CA A:GLY345 4.4 30.8 1.0 N A:SER298 4.4 26.2 1.0 CA A:SER298 4.4 26.3 1.0 C A:ASN294 4.4 31.4 1.0 O A:ASN344 4.5 34.5 1.0 N A:GLY297 4.5 27.8 1.0 N A:TRP295 4.6 29.2 1.0 CA A:GLY297 4.6 26.6 1.0 CA A:ASP293 4.7 23.2 1.0 OD1 A:ASP293 4.8 26.0 1.0 CB A:ASP293 4.8 24.4 1.0 N A:ASP293 4.8 23.2 1.0 O A:PRO326 4.9 29.8 1.0 CA A:PRO347 4.9 34.0 1.0 O A:ASN294 5.0 33.0 1.0

Calcium binding site 2 out of 2 in the The Crystal Structure of Influenza A Neuraminidase N3


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of The Crystal Structure of Influenza A Neuraminidase N3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca508 b:61.0 occ:0.25 O A:HOH684 2.9 32.0 1.0 OD1 A:ASP113 3.8 25.1 1.0 O A:HOH844 4.1 28.9 1.0 O A:HOH734 4.5 23.4 1.0 CG A:ASP113 4.9 23.2 1.0

Q.Li, J.Qi, Y.Wu, H.Kiyota, K.Tanaka, Y.Suhara, H.Ohrui, Y.Suzuki, C.J.Vavricka, G.F.Gao. Functional and Structural Analysis of Influenza Virus Neuraminidase N3 Offers Further Insight Into the Mechanisms of Oseltamivir Resistance. J.Virol. V. 87 10016 2013.
ISSN: ISSN 0022-538X
PubMed: 23824808
DOI: 10.1128/JVI.01129-13