Calcium in PDB 4kpp: Crystal Structure of H+/CA2+ Exchanger Cax

The structure of Crystal Structure of H+/CA2+ Exchanger Cax, PDB code: 4kpp was solved by T.Nishizawa, R.Ishitani, O.Nureki, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.71 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	63.954, 97.386, 71.233, 90.00, 99.37, 90.00
R / Rfree (%)	20.2 / 23.8

The binding sites of Calcium atom in the Crystal Structure of H+/CA2+ Exchanger Cax (pdb code 4kpp). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of H+/CA2+ Exchanger Cax, PDB code: 4kpp:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of H+/CA2+ Exchanger Cax


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of H+/CA2+ Exchanger Cax within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca501 b:63.9 occ:1.00 O A:LYS335 2.1 45.6 1.0 OE1 A:GLU340 2.2 40.3 1.0 OD1 A:ASP333 2.4 55.3 1.0 OE2 A:GLU340 2.5 42.5 1.0 O A:ILE330 2.5 31.9 1.0 CD A:GLU340 2.7 41.0 1.0 OD2 A:ASP333 2.7 62.0 1.0 CG A:ASP333 2.9 57.7 1.0 C A:LYS335 3.3 47.9 1.0 C A:ILE330 3.6 25.0 1.0 CG2 A:ILE330 3.8 40.7 1.0 N A:ILE336 4.1 50.6 1.0 CA A:ILE336 4.1 48.0 1.0 CG A:GLU340 4.2 40.4 1.0 CA A:ILE330 4.2 27.6 1.0 O A:HOH610 4.2 27.6 1.0 CA A:LYS335 4.2 45.1 1.0 N A:LYS335 4.3 44.8 1.0 CB A:ASP333 4.4 53.3 1.0 CB A:LYS335 4.5 45.6 1.0 N A:SER337 4.5 45.8 1.0 CB A:ILE330 4.6 36.6 1.0 N A:LEU331 4.8 24.1 1.0 CB A:GLU340 4.8 40.9 1.0 C A:ILE336 4.9 44.6 1.0 N A:ASP333 4.9 42.9 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of H+/CA2+ Exchanger Cax


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of H+/CA2+ Exchanger Cax within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca501 b:61.0 occ:1.00 O B:ILE330 2.1 36.5 1.0 OD1 B:ASP333 2.2 41.7 1.0 O B:LYS335 2.3 42.8 1.0 OE2 B:GLU340 2.6 34.0 1.0 OE1 B:GLU340 2.7 31.3 1.0 CD B:GLU340 3.0 33.2 1.0 CG B:ASP333 3.1 38.2 1.0 C B:ILE330 3.3 32.8 1.0 C B:LYS335 3.3 41.2 1.0 OD2 B:ASP333 3.4 40.4 1.0 O B:HOH612 3.4 32.4 1.0 CG2 B:ILE330 3.9 46.2 1.0 CA B:ILE330 4.0 32.8 1.0 N B:LYS335 4.1 41.5 1.0 CA B:LYS335 4.1 42.9 1.0 N B:ILE336 4.3 39.4 1.0 N B:LEU331 4.3 32.9 1.0 CA B:ILE336 4.4 36.0 1.0 CB B:LYS335 4.4 48.2 1.0 CG B:GLU340 4.5 34.1 1.0 CB B:ASP333 4.5 34.4 1.0 CB B:ILE330 4.5 39.6 1.0 CA B:LEU331 4.6 29.1 1.0 N B:ASP333 4.6 27.2 1.0 C B:LEU331 4.8 30.3 1.0 N B:SER337 4.9 36.1 1.0 CA B:ASP333 4.9 31.9 1.0

T.Nishizawa, S.Kita, A.D.Maturana, N.Furuya, K.Hirata, G.Kasuya, S.Ogasawara, N.Dohmae, T.Iwamoto, R.Ishitani, O.Nureki. Structural Basis For the Counter-Transport Mechanism of A H+/CA2+ Exchanger Science 2013.
ISSN: ESSN 1095-9203
PubMed: 23704374
DOI: 10.1126/SCIENCE.1239002