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Calcium in PDB 4l03: Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-KetoglutarateEnzymatic activity of Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate
All present enzymatic activity of Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate:
1.1.1.42; Protein crystallography data
The structure of Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate, PDB code: 4l03
was solved by
N.O.Concha,
A.M.Smallwood,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate
(pdb code 4l03). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate, PDB code: 4l03: Jump to Calcium binding site number: 1; 2; 3; Calcium binding site 1 out of 3 in 4l03Go back to Calcium Binding Sites List in 4l03
Calcium binding site 1 out
of 3 in the Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate
Mono view Stereo pair view
Calcium binding site 2 out of 3 in 4l03Go back to Calcium Binding Sites List in 4l03
Calcium binding site 2 out
of 3 in the Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate
Mono view Stereo pair view
Calcium binding site 3 out of 3 in 4l03Go back to Calcium Binding Sites List in 4l03
Calcium binding site 3 out
of 3 in the Crystal Structure Analysis of Human IDH1 Mutants in Complex with Nadp+ and CA2+/Alpha-Ketoglutarate
Mono view Stereo pair view
Reference:
A.R.Rendina,
B.Pietrak,
A.Smallwood,
H.Zhao,
H.Qi,
C.Quinn,
N.D.Adams,
N.Concha,
C.Duraiswami,
S.H.Thrall,
S.Sweitzer,
B.Schwartz.
Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism. Biochemistry V. 52 4563 2013.
Page generated: Sat Dec 12 04:56:05 2020
ISSN: ISSN 0006-2960 PubMed: 23731180 DOI: 10.1021/BI400514K |
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