Calcium in PDB 4m1l: Complex of Iqcg and CA2+-Bound Cam

The structure of Complex of Iqcg and CA2+-Bound Cam, PDB code: 4m1l was solved by W.X.Liang, L.T.Chen, Z.Chen, S.J.Chen, S.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.64 / 2.10
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	40.491, 40.491, 179.689, 90.00, 90.00, 120.00
R / Rfree (%)	18.7 / 22.8

The binding sites of Calcium atom in the Complex of Iqcg and CA2+-Bound Cam (pdb code 4m1l). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Complex of Iqcg and CA2+-Bound Cam, PDB code: 4m1l:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Complex of Iqcg and CA2+-Bound Cam


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Complex of Iqcg and CA2+-Bound Cam within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca201 b:22.3 occ:1.00 O A:THR27 2.3 28.3 1.0 OD1 A:ASP21 2.3 24.8 1.0 OD1 A:ASP25 2.4 27.6 1.0 OD1 A:ASP23 2.4 26.5 1.0 OE2 A:GLU32 2.4 26.8 1.0 O A:HOH318 2.5 21.4 1.0 OE1 A:GLU32 2.7 27.6 1.0 CD A:GLU32 2.9 24.9 1.0 CG A:ASP25 3.2 34.3 1.0 CG A:ASP23 3.2 31.9 1.0 OD2 A:ASP23 3.5 34.6 1.0 CG A:ASP21 3.5 25.2 1.0 C A:THR27 3.5 24.4 1.0 OD2 A:ASP25 3.7 37.5 1.0 OG1 A:THR27 4.1 43.8 1.0 N A:THR27 4.1 21.7 1.0 N A:ASP25 4.2 31.2 1.0 OD2 A:ASP21 4.3 27.1 1.0 CA A:ASP21 4.3 21.4 1.0 CA A:THR27 4.3 27.9 1.0 CB A:ASP21 4.4 21.4 1.0 CB A:ASP25 4.4 34.9 1.0 CG A:GLU32 4.4 21.5 1.0 N A:ASP23 4.4 29.4 1.0 N A:ILE28 4.5 16.6 1.0 C A:ASP21 4.6 22.9 1.0 N A:GLY24 4.6 28.8 1.0 CB A:ASP23 4.6 32.1 1.0 CA A:ILE28 4.6 14.9 1.0 O4 A:SO4205 4.6 52.0 1.0 N A:LYS22 4.7 27.0 1.0 CA A:ASP25 4.7 34.0 1.0 O A:HOH321 4.7 31.0 1.0 N A:GLY26 4.8 27.6 1.0 CB A:THR27 4.8 38.6 1.0 CA A:ASP23 4.9 31.9 1.0 N A:THR29 4.9 19.5 1.0 CG2 A:THR29 4.9 21.3 1.0 C A:ASP25 4.9 32.7 1.0 C A:ASP23 5.0 32.0 1.0

Calcium binding site 2 out of 4 in the Complex of Iqcg and CA2+-Bound Cam


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Complex of Iqcg and CA2+-Bound Cam within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca202 b:31.1 occ:1.00 OD1 A:ASP57 2.3 36.9 1.0 OD1 A:ASN61 2.3 39.0 1.0 O A:THR63 2.4 27.3 1.0 O A:HOH356 2.4 46.6 1.0 OE2 A:GLU68 2.4 30.4 1.0 OD1 A:ASP59 2.5 47.1 1.0 OE1 A:GLU68 2.5 28.8 1.0 CD A:GLU68 2.8 29.5 1.0 CG A:ASN61 3.3 42.9 1.0 CG A:ASP59 3.3 52.7 1.0 CG A:ASP57 3.4 40.1 1.0 OD2 A:ASP59 3.6 55.3 1.0 C A:THR63 3.6 25.9 1.0 ND2 A:ASN61 3.7 44.9 1.0 OD2 A:ASP57 4.2 41.0 1.0 CG A:GLU68 4.3 27.5 1.0 N A:THR63 4.4 34.2 1.0 CA A:ILE64 4.4 23.6 1.0 CA A:ASP57 4.4 39.8 1.0 N A:ILE64 4.4 24.1 1.0 CB A:ASP57 4.4 39.3 1.0 N A:ASN61 4.4 42.5 1.0 N A:ASP65 4.4 22.1 1.0 CB A:ASN61 4.5 44.0 1.0 N A:ASP59 4.5 49.6 1.0 CA A:THR63 4.5 29.0 1.0 OG1 A:THR63 4.5 29.0 1.0 C A:ASP57 4.6 43.5 1.0 CB A:ASP59 4.6 53.1 1.0 N A:ALA58 4.7 44.8 1.0 CG A:ASP65 4.8 40.3 1.0 N A:GLY60 4.8 45.9 1.0 C A:ILE64 4.9 20.7 1.0 CA A:ASN61 4.9 40.6 1.0 OD1 A:ASP65 4.9 41.3 1.0 OD2 A:ASP65 4.9 45.6 1.0 CA A:ASP59 4.9 51.9 1.0 N A:GLY62 4.9 32.6 1.0

Calcium binding site 3 out of 4 in the Complex of Iqcg and CA2+-Bound Cam


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Complex of Iqcg and CA2+-Bound Cam within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca203 b:20.1 occ:1.00 O A:TYR100 2.3 20.9 1.0 OD1 A:ASP94 2.4 21.0 1.0 OD1 A:ASN98 2.4 15.4 1.0 OD1 A:ASP96 2.4 31.2 1.0 O A:HOH317 2.4 30.3 1.0 OE2 A:GLU105 2.5 22.2 1.0 OE1 A:GLU105 2.5 21.2 1.0 CD A:GLU105 2.9 20.5 1.0 CG A:ASP96 3.3 26.9 1.0 CG A:ASN98 3.4 18.3 1.0 C A:TYR100 3.5 19.2 1.0 CG A:ASP94 3.5 23.9 1.0 OD2 A:ASP96 3.5 27.1 1.0 ND2 A:ASN98 4.1 16.8 1.0 N A:TYR100 4.1 15.7 1.0 N A:ASN98 4.2 20.2 1.0 CA A:ASP94 4.2 22.8 1.0 CA A:TYR100 4.3 17.2 1.0 CG A:GLU105 4.4 20.2 1.0 OD2 A:ASP94 4.4 20.8 1.0 CB A:ASP94 4.4 23.7 1.0 CB A:ASN98 4.4 19.5 1.0 N A:ILE101 4.5 19.8 1.0 N A:ASP96 4.5 24.1 1.0 N A:GLY97 4.5 24.4 1.0 CA A:ILE101 4.6 17.0 1.0 C A:ASP94 4.6 23.9 1.0 CB A:ASP96 4.6 26.7 1.0 CA A:ASN98 4.7 21.7 1.0 N A:GLY99 4.8 19.9 1.0 N A:LYS95 4.8 28.9 1.0 N A:SER102 4.8 18.8 1.0 CB A:TYR100 4.8 13.6 1.0 CA A:ASP96 4.9 26.2 1.0 C A:ASP96 5.0 26.5 1.0 C A:ASN98 5.0 21.5 1.0

Calcium binding site 4 out of 4 in the Complex of Iqcg and CA2+-Bound Cam


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Complex of Iqcg and CA2+-Bound Cam within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca204 b:16.4 occ:1.00 OD1 A:ASP130 2.3 16.8 1.0 OD1 A:ASP134 2.3 19.9 1.0 O A:HOH316 2.4 16.2 1.0 O A:GLN136 2.4 18.7 1.0 OD1 A:ASP132 2.4 21.2 1.0 OE2 A:GLU141 2.5 18.0 1.0 OE1 A:GLU141 2.5 16.2 1.0 CD A:GLU141 2.8 14.6 1.0 CG A:ASP132 3.2 28.2 1.0 CG A:ASP134 3.2 22.2 1.0 CG A:ASP130 3.4 17.6 1.0 OD2 A:ASP132 3.4 29.2 1.0 C A:GLN136 3.5 17.8 1.0 OD2 A:ASP134 3.6 21.1 1.0 OD2 A:ASP130 4.1 16.8 1.0 N A:ASP134 4.1 18.0 1.0 N A:ASP132 4.2 18.5 1.0 N A:GLN136 4.2 14.5 1.0 N A:ILE131 4.2 13.6 1.0 CG A:GLU141 4.3 13.3 1.0 N A:GLY133 4.4 15.3 1.0 N A:VAL137 4.4 15.5 1.0 CB A:ASP134 4.4 22.9 1.0 CB A:ASP130 4.4 14.3 1.0 CA A:GLN136 4.4 14.6 1.0 CA A:ASP130 4.4 15.3 1.0 CA A:VAL137 4.4 13.6 1.0 N A:ASN138 4.5 15.5 1.0 CB A:ASP132 4.5 22.5 1.0 CA A:ASP134 4.7 20.6 1.0 CA A:ASP132 4.7 21.9 1.0 N A:GLY135 4.8 15.7 1.0 C A:ASP130 4.8 16.2 1.0 C A:ASP132 4.9 15.7 1.0 CB A:GLN136 4.9 9.8 1.0 C A:VAL137 4.9 15.1 1.0

L.T.Chen, W.X.Liang, S.Chen, R.K.Li, J.L.Tan, P.F.Xu, L.F.Luo, L.Wang, S.H.Yu, G.Y.Meng, K.K.Li, T.X.Liu, Z.Chen, S.J.Chen. Functional and Molecular Features of A Calmodulin-Interacting Protein Iqcg Required For Haematopoiesis in Zebrafish Nat Commun V. 5 3811 2014.
ISSN: ESSN 2041-1723
DOI: 10.1038/NCOMMS4811