Atomistry » Calcium » PDB 4mpr-4mzx » 4msp
Atomistry »
  Calcium »
    PDB 4mpr-4mzx »
      4msp »

Calcium in PDB 4msp: Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs

Enzymatic activity of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs

All present enzymatic activity of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs:
5.2.1.8;

Protein crystallography data

The structure of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs, PDB code: 4msp was solved by S.P.Boudko, Y.Ishikawa, H.P.Bachinger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 23.19 / 1.90
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 36.430, 101.200, 58.970, 90.00, 100.01, 90.00
R / Rfree (%) 15.8 / 20

Calcium Binding Sites:

The binding sites of Calcium atom in the Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs (pdb code 4msp). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs, PDB code: 4msp:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in 4msp

Go back to Calcium Binding Sites List in 4msp
Calcium binding site 1 out of 5 in the Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca201

b:38.0
occ:1.00
 O A:LYS135 2.2 37.2 1.0
OD1 A:ASN131 2.3 45.0 1.0
OD1 A:ASP129 2.3 36.8 1.0
OD1 A:ASP133 2.4 39.8 1.0
O A:HOH345 2.4 36.4 1.0
OE2 A:GLU140 2.5 39.9 1.0
OE1 A:GLU140 2.6 39.6 1.0
CD A:GLU140 2.9 37.2 1.0
CG A:ASP133 3.3 44.3 1.0
CG A:ASN131 3.4 44.0 1.0
C A:LYS135 3.4 37.6 1.0
CG A:ASP129 3.5 41.9 1.0
OD2 A:ASP133 3.7 49.5 1.0
ND2 A:ASN131 4.0 45.9 1.0
N A:ASP133 4.2 45.9 1.0
CA A:ASP129 4.2 34.8 1.0
N A:ASN131 4.2 35.2 1.0
N A:LYS135 4.2 46.8 1.0
CA A:LEU136 4.3 35.5 1.0
OD2 A:ASP129 4.3 41.5 1.0
N A:LEU136 4.3 38.5 1.0
CB A:ASP129 4.4 33.4 1.0
CG A:GLU140 4.4 33.4 1.0
C A:ASP129 4.4 41.8 1.0
N A:SER137 4.4 37.5 1.0
CA A:LYS135 4.4 41.4 1.0
CB A:ASP133 4.5 42.4 1.0
CB A:ASN131 4.5 40.5 1.0
N A:LEU130 4.6 36.9 1.0
N A:ASP132 4.6 43.5 1.0
CG A:LYS135 4.7 43.7 1.0
O A:HOH323 4.7 42.2 1.0
CA A:ASN131 4.7 38.1 1.0
CA A:ASP133 4.7 47.0 1.0
C A:ASN131 4.8 44.0 1.0
C A:LEU136 4.8 41.1 1.0
N A:TRP134 4.9 42.6 1.0
O A:HOH350 4.9 55.9 1.0
C A:ASP133 4.9 44.6 1.0
O A:ASP129 4.9 37.0 1.0

Calcium binding site 2 out of 5 in 4msp

Go back to Calcium Binding Sites List in 4msp
Calcium binding site 2 out of 5 in the Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca202

b:48.7
occ:1.00
 OD1 A:ASP173 2.3 56.1 1.0
OD2 A:ASP175 2.3 51.4 1.0
OD1 A:ASP177 2.4 57.0 1.0
O A:PHE179 2.5 49.8 1.0
O A:HOH358 2.6 57.4 1.0
OE1 A:GLU184 2.6 67.1 1.0
OE2 A:GLU184 2.8 65.0 1.0
CD A:GLU184 3.1 63.5 1.0
CG A:ASP173 3.4 52.5 1.0
CG A:ASP175 3.4 64.5 1.0
CG A:ASP177 3.5 60.8 1.0
C A:PHE179 3.5 48.5 1.0
OD1 A:ASP175 3.9 65.6 1.0
OD2 A:ASP177 4.1 61.7 1.0
N A:PHE179 4.1 48.9 1.0
N A:ASP177 4.1 60.2 1.0
N A:GLU174 4.2 53.0 1.0
OD2 A:ASP173 4.2 52.5 1.0
CA A:ASP173 4.2 49.2 1.0
CA A:PHE179 4.3 49.2 1.0
CB A:ASP173 4.3 47.2 1.0
N A:ASP175 4.3 67.4 1.0
N A:LYS176 4.4 62.9 1.0
N A:ILE180 4.4 42.9 1.0
N A:SER181 4.4 47.8 1.0
CA A:ILE180 4.5 43.1 1.0
C A:ASP173 4.6 50.5 1.0
CB A:PHE179 4.6 47.3 1.0
CG A:GLU184 4.6 60.0 1.0
CB A:ASP177 4.6 60.8 1.0
CB A:ASP175 4.7 65.3 1.0
CA A:ASP177 4.8 61.8 1.0
N A:GLY178 4.8 56.6 1.0
CA A:ASP175 4.8 63.2 1.0
C A:ASP175 4.9 58.0 1.0
CA A:LYS176 5.0 56.8 1.0

Calcium binding site 3 out of 5 in 4msp

Go back to Calcium Binding Sites List in 4msp
Calcium binding site 3 out of 5 in the Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca203

b:72.6
occ:1.00
 O A:GLU184 2.4 55.2 1.0
ND1 A:HIS189 2.5 0.3 1.0
O A:TYR187 2.5 74.5 1.0
OE1 A:GLU172 2.6 56.8 1.0
CE1 A:HIS189 3.1 0.9 1.0
C A:GLU184 3.6 54.3 1.0
CG A:HIS189 3.6 0.6 1.0
CD A:GLU172 3.6 58.6 1.0
C A:TYR187 3.7 71.9 1.0
N A:HIS189 3.8 96.2 1.0
OE2 A:GLU172 4.1 66.2 1.0
NH1 A:ARG120 4.2 44.3 1.0
CB A:HIS189 4.2 0.4 1.0
NE2 A:HIS189 4.3 0.7 1.0
CA A:GLU184 4.3 57.3 1.0
OE2 A:GLU174 4.4 91.3 1.0
CA A:LYS188 4.5 72.1 1.0
N A:LYS188 4.6 69.2 1.0
CD2 A:HIS189 4.6 0.8 1.0
C A:LYS188 4.6 88.5 1.0
CA A:HIS189 4.6 0.6 1.0
N A:PHE185 4.6 44.7 1.0
N A:TYR187 4.6 67.3 1.0
CA A:TYR187 4.7 69.6 1.0
CA A:GLU172 4.7 46.0 1.0
O A:GLU172 4.8 51.2 1.0
CB A:GLU184 4.8 54.3 1.0
CA A:PHE185 4.8 49.9 1.0
C A:PHE185 4.8 53.2 1.0
CG A:GLU172 4.8 50.1 1.0
CB A:GLU172 4.9 46.1 1.0
O A:PHE185 4.9 43.8 1.0

Calcium binding site 4 out of 5 in 4msp

Go back to Calcium Binding Sites List in 4msp
Calcium binding site 4 out of 5 in the Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca201

b:26.5
occ:1.00
 OD1 B:ASP129 2.2 23.3 1.0
OD1 B:ASP133 2.3 29.3 1.0
O B:LYS135 2.4 24.7 1.0
OD1 B:ASN131 2.4 25.5 1.0
OE1 B:GLU140 2.4 30.9 1.0
O B:HOH308 2.5 29.2 1.0
OE2 B:GLU140 2.5 25.9 1.0
CD B:GLU140 2.8 33.1 1.0
CG B:ASP133 3.2 30.2 1.0
CG B:ASN131 3.4 26.7 1.0
CG B:ASP129 3.4 22.3 1.0
C B:LYS135 3.6 29.3 1.0
OD2 B:ASP133 3.6 28.8 1.0
ND2 B:ASN131 3.9 30.5 1.0
N B:ASP133 4.2 28.6 1.0
CA B:ASP129 4.2 21.8 1.0
OD2 B:ASP129 4.2 23.4 1.0
N B:ASN131 4.3 33.0 1.0
N B:LYS135 4.3 26.1 1.0
CG B:GLU140 4.3 29.4 1.0
CB B:ASP129 4.3 21.9 1.0
CA B:LEU136 4.3 24.6 1.0
N B:LEU136 4.4 26.6 1.0
CB B:ASP133 4.4 30.1 1.0
C B:ASP129 4.4 24.2 1.0
CA B:LYS135 4.5 28.6 1.0
N B:LEU130 4.6 22.9 1.0
N B:ASP132 4.6 24.2 1.0
N B:SER137 4.6 28.0 1.0
CB B:ASN131 4.6 26.1 1.0
CG B:LYS135 4.7 27.5 1.0
CA B:ASP133 4.7 26.6 1.0
CA B:ASN131 4.7 28.0 1.0
O B:HOH350 4.8 39.8 1.0
C B:ASN131 4.8 31.5 1.0
O B:HOH319 4.8 29.8 1.0
N B:TRP134 4.9 26.5 1.0
C B:LEU136 4.9 29.1 1.0
C B:ASP133 4.9 31.8 1.0

Calcium binding site 5 out of 5 in 4msp

Go back to Calcium Binding Sites List in 4msp
Calcium binding site 5 out of 5 in the Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Crystal Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 (Aka FKBP14) Containing Two Ef-Hand Motifs within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca202

b:32.6
occ:1.00
 O B:HOH428 2.3 40.3 1.0
OD1 B:ASP173 2.3 39.2 1.0
OD1 B:ASP175 2.3 35.1 1.0
O B:PHE179 2.4 31.1 1.0
OE1 B:GLU184 2.4 27.0 1.0
OD1 B:ASP177 2.4 34.9 1.0
OE2 B:GLU184 2.6 32.9 1.0
CD B:GLU184 2.8 29.6 1.0
CG B:ASP175 3.4 44.1 1.0
CG B:ASP173 3.4 35.7 1.0
CG B:ASP177 3.4 33.3 1.0
C B:PHE179 3.5 30.2 1.0
OD2 B:ASP175 3.9 51.2 1.0
OD2 B:ASP177 3.9 36.5 1.0
CA B:ASP173 4.2 30.7 1.0
OD2 B:ASP173 4.2 35.6 1.0
N B:ASP177 4.2 38.1 1.0
N B:PHE179 4.2 35.5 1.0
N B:ASP175 4.2 45.1 1.0
CB B:ASP173 4.3 34.7 1.0
CA B:PHE179 4.3 28.5 1.0
CG B:GLU184 4.3 27.4 1.0
N B:GLU174 4.4 40.5 1.0
C B:ASP173 4.4 37.8 1.0
N B:LYS176 4.4 47.0 1.0
N B:ILE180 4.4 25.2 1.0
N B:SER181 4.4 25.9 1.0
CA B:ILE180 4.4 24.7 1.0
CB B:ASP177 4.5 37.8 1.0
CB B:ASP175 4.6 42.5 1.0
CA B:ASP175 4.7 44.0 1.0
CB B:PHE179 4.7 30.1 1.0
C B:ASP175 4.7 50.0 1.0
CA B:ASP177 4.8 39.5 1.0
C B:ILE180 4.9 27.0 1.0
N B:GLY178 5.0 38.4 1.0

Reference:

S.P.Boudko, Y.Ishikawa, J.Nix, M.S.Chapman, H.P.Bachinger. Structure of Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP22 Containing Two Ef-Hand Motifs. Protein Sci. V. 23 67 2014.
ISSN: ISSN 0961-8368
PubMed: 24272907
DOI: 10.1002/PRO.2391
Page generated: Sun Jul 14 10:32:54 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy