Calcium in PDB 4mtg: Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel

The structure of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel, PDB code: 4mtg was solved by L.Tang, T.M.Gamal El-Din, J.Payandeh, G.Q.Martinez, T.M.Heard, T.Scheuer, N.Zheng, W.A.Catterall, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.86 / 3.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	177.250, 177.740, 131.020, 90.00, 132.59, 90.00
R / Rfree (%)	23.9 / 27.3

The binding sites of Calcium atom in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel (pdb code 4mtg). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel, PDB code: 4mtg:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1301 b:0.4 occ:1.00 OD1 B:ASP1177 4.2 67.3 1.0 OD1 D:ASP1177 4.4 64.0 1.0 N B:ASP1178 4.4 63.4 1.0 N A:ASP1178 4.4 67.5 1.0 OD1 A:ASP1177 4.5 72.6 1.0 OD1 C:ASP1177 4.5 61.0 1.0 O A:LEU1176 4.5 54.5 1.0 N D:ASP1178 4.6 68.0 1.0 O B:LEU1176 4.6 56.0 1.0 N C:ASP1178 4.6 65.7 1.0 CA A:CA1302 4.6 58.6 1.0 CA B:ASP1177 4.8 65.0 1.0 O D:LEU1176 4.8 59.1 1.0 CA A:ASP1177 4.8 67.8 1.0 CA D:ASP1177 4.9 74.5 1.0 O C:LEU1176 4.9 56.0 1.0 CA C:ASP1177 5.0 67.2 1.0

Calcium binding site 2 out of 2 in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1302 b:58.6 occ:1.00 CG A:ASP1178 4.0 65.2 1.0 CG D:ASP1178 4.0 73.0 1.0 CG B:ASP1178 4.1 67.6 1.0 CG C:ASP1178 4.1 61.9 1.0 CB D:ASP1178 4.1 74.8 1.0 OD2 A:ASP1178 4.1 59.9 1.0 OD1 D:ASP1178 4.2 65.8 1.0 CB A:ASP1178 4.2 64.1 1.0 CB C:ASP1178 4.2 63.1 1.0 OD1 A:ASP1178 4.2 59.6 1.0 OD1 B:ASP1178 4.2 59.2 1.0 OD1 C:ASP1178 4.2 52.8 1.0 OD2 D:ASP1178 4.3 66.5 1.0 CB B:ASP1178 4.3 64.5 1.0 OD2 B:ASP1178 4.4 69.3 1.0 OD2 C:ASP1178 4.4 61.5 1.0 CA A:CA1301 4.6 0.4 1.0 CA D:ASP1178 4.7 68.8 1.0 CA A:ASP1178 4.8 66.7 1.0 CA B:ASP1178 4.8 65.1 1.0 CA C:ASP1178 4.8 62.0 1.0

L.Tang, T.M.Gamal El-Din, J.Payandeh, G.Q.Martinez, T.M.Heard, T.Scheuer, N.Zheng, W.A.Catterall. Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel. Nature V. 505 56 2014.
ISSN: ISSN 0028-0836
PubMed: 24270805
DOI: 10.1038/NATURE12775