Calcium in PDB 4mw8: Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel

The structure of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel, PDB code: 4mw8 was solved by L.Tang, T.M.Gamal El-Din, J.Payandeh, G.Q.Martinez, T.M.Heard, T.Scheuer, N.Zheng, W.A.Catterall, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.13 / 3.26
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	229.218, 124.883, 124.763, 90.00, 122.95, 90.00
R / Rfree (%)	27.6 / 31.4

The binding sites of Calcium atom in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel (pdb code 4mw8). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel, PDB code: 4mw8:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1301 b:62.0 occ:1.00 OG A:SER1178 2.7 62.0 1.0 OG D:SER1178 3.0 62.3 1.0 OG B:SER1178 3.1 62.9 1.0 OG C:SER1178 3.1 62.2 1.0 CB A:SER1178 4.1 62.6 1.0 CB D:SER1178 4.3 64.5 1.0 CB B:SER1178 4.4 63.4 1.0 CA A:CA1302 4.4 89.4 1.0 CB C:SER1178 4.5 62.4 1.0 CA A:SER1178 4.7 63.0 1.0 CA D:SER1178 4.8 64.0 1.0 CA B:SER1178 4.9 64.6 1.0 N A:SER1178 4.9 64.7 1.0 CA C:SER1178 4.9 62.6 1.0

Calcium binding site 2 out of 2 in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1302 b:89.4 occ:1.00 N A:SER1178 4.1 64.7 1.0 N B:SER1178 4.3 65.9 1.0 CA A:GLU1177 4.4 63.6 1.0 CA A:CA1301 4.4 62.0 1.0 O A:LEU1176 4.5 63.6 1.0 CA B:GLU1177 4.5 64.5 1.0 N D:SER1178 4.6 67.7 1.0 CG A:GLU1177 4.6 62.0 1.0 O B:LEU1176 4.6 64.6 1.0 CG B:GLU1177 4.7 62.5 1.0 N C:SER1178 4.7 64.0 1.0 CA D:GLU1177 4.7 66.4 1.0 C A:GLU1177 4.7 63.9 1.0 CG D:GLU1177 4.8 63.5 1.0 O D:LEU1176 4.9 64.5 1.0 CA C:GLU1177 4.9 63.4 1.0 CB A:GLU1177 4.9 62.2 1.0 O C:LEU1176 4.9 62.8 1.0 C B:GLU1177 4.9 64.0 1.0 CB B:GLU1177 4.9 62.6 1.0 CG C:GLU1177 5.0 62.3 1.0

L.Tang, T.M.Gamal El-Din, J.Payandeh, G.Q.Martinez, T.M.Heard, T.Scheuer, N.Zheng, W.A.Catterall. Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel. Nature V. 505 56 2014.
ISSN: ISSN 0028-0836
PubMed: 24270805
DOI: 10.1038/NATURE12775