Calcium in PDB 4mza: Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase

All present enzymatic activity of Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase:
3.2.1.18;

The structure of Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase, PDB code: 4mza was solved by R.Xu, I.A.Wilson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.42 / 1.65
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	83.782, 94.839, 105.499, 90.00, 90.00, 90.00
R / Rfree (%)	16.7 / 19.8

The binding sites of Calcium atom in the Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase (pdb code 4mza). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase, PDB code: 4mza:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca612 b:22.2 occ:1.00 O A:GLY284 2.3 26.4 1.0 O A:ALA316 2.3 19.7 1.0 O A:ASP279 2.4 23.9 1.0 OG A:SER282 2.4 24.9 1.0 O A:SER282 2.4 23.8 1.0 OD1 A:ASP279 2.4 21.4 1.0 O A:HOH803 2.4 28.2 1.0 C A:ASP279 3.3 23.7 1.0 C A:SER282 3.4 29.5 1.0 C A:ALA316 3.5 20.6 1.0 C A:GLY284 3.5 22.8 1.0 CG A:ASP279 3.6 24.3 1.0 CB A:SER282 3.6 27.5 1.0 CA A:ASP279 3.7 21.6 1.0 CA A:SER282 3.9 32.1 1.0 O A:HOH817 4.1 33.4 1.0 N A:SER282 4.1 27.2 1.0 CA A:ALA316 4.2 21.5 1.0 O A:SER283 4.2 29.7 1.0 CA A:ILE285 4.2 18.6 1.0 C A:SER283 4.2 28.0 1.0 CB A:ASP279 4.3 23.4 1.0 N A:ILE285 4.3 19.2 1.0 N A:GLY284 4.4 24.2 1.0 O A:HOH790 4.4 45.5 1.0 N A:SER283 4.5 32.3 1.0 N A:TYR280 4.5 22.6 1.0 N A:ALA317 4.5 17.6 1.0 CA A:GLY284 4.5 23.7 1.0 OD2 A:ASP279 4.6 21.2 1.0 C A:ILE285 4.6 23.0 1.0 CB A:ALA316 4.7 23.7 1.0 CA A:ALA317 4.7 18.0 1.0 OE2 A:GLU286 4.8 37.5 1.0 CA A:SER283 4.8 27.0 1.0 O A:SER278 4.8 28.1 1.0 N A:GLU286 4.8 23.5 1.0 CA A:TYR280 4.9 24.8 1.0 CB A:ALA317 5.0 20.0 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of HPIV3 Hemagglutinin-Neuraminidase within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca610 b:24.6 occ:1.00 O B:GLY284 2.3 26.8 1.0 O B:ALA316 2.3 25.4 1.0 O B:ASP279 2.4 27.7 1.0 OD1 B:ASP279 2.4 22.6 1.0 O B:HOH732 2.4 32.0 1.0 O B:SER282 2.4 26.5 1.0 OG B:SER282 2.5 27.6 1.0 C B:ASP279 3.3 29.4 1.0 C B:SER282 3.4 31.1 1.0 C B:ALA316 3.5 28.3 1.0 C B:GLY284 3.5 28.7 1.0 CG B:ASP279 3.6 23.8 1.0 CB B:SER282 3.7 29.9 1.0 CA B:ASP279 3.7 26.1 1.0 CA B:SER282 3.9 31.6 1.0 N B:SER282 4.0 31.8 1.0 O B:SER283 4.1 30.0 1.0 O B:HOH807 4.2 40.7 1.0 C B:SER283 4.2 29.8 1.0 CA B:ALA316 4.2 27.8 1.0 CA B:ILE285 4.3 20.7 1.0 CB B:ASP279 4.3 24.4 1.0 N B:GLY284 4.4 29.9 1.0 N B:ILE285 4.4 23.5 1.0 N B:SER283 4.4 32.9 1.0 O B:HOH928 4.5 52.5 1.0 N B:TYR280 4.5 27.4 1.0 OD2 B:ASP279 4.5 24.2 1.0 CA B:GLY284 4.5 27.9 1.0 N B:ALA317 4.5 19.7 1.0 CB B:ALA316 4.6 26.6 1.0 C B:ILE285 4.7 25.6 1.0 CA B:ALA317 4.7 20.5 1.0 CA B:SER283 4.8 33.7 1.0 O B:SER278 4.8 30.2 1.0 N B:GLU286 4.9 26.3 1.0 CB B:ALA317 4.9 20.9 1.0 CA B:TYR280 4.9 29.4 1.0 OE2 B:GLU286 4.9 35.0 1.0

R.Xu, S.G.Palmer, M.Porotto, L.M.Palermo, S.Niewiesk, I.A.Wilson, A.Moscona. Interaction Between the Hemagglutinin-Neuraminidase and Fusion Glycoproteins of Human Parainfluenza Virus Type III Regulates Viral Growth in Vivo. Mbio V. 4 00803 2013.
ISSN: ESSN 2150-7511
PubMed: 24149514
DOI: 10.1128/MBIO.00803-13