Atomistry » Calcium » PDB 4olk-4p2p » 4orb
Atomistry »
  Calcium »
    PDB 4olk-4p2p »
      4orb »

Calcium in PDB 4orb: Crytal Structure of Mouse Calcineurin

Enzymatic activity of Crytal Structure of Mouse Calcineurin

All present enzymatic activity of Crytal Structure of Mouse Calcineurin:
3.1.3.16;

Protein crystallography data

The structure of Crytal Structure of Mouse Calcineurin, PDB code: 4orb was solved by L.Ma, S.J.Li, J.Wang, J.W.Wu, Z.X.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.69 / 3.11
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 48.865, 107.466, 175.823, 90.00, 90.00, 90.00
R / Rfree (%) 19.6 / 24.3

Other elements in 4orb:

The structure of Crytal Structure of Mouse Calcineurin also contains other interesting chemical elements:

Iron (Fe) 1 atom
Zinc (Zn) 1 atom

Calcium Binding Sites:

The binding sites of Calcium atom in the Crytal Structure of Mouse Calcineurin (pdb code 4orb). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Crytal Structure of Mouse Calcineurin, PDB code: 4orb:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in 4orb

Go back to Calcium Binding Sites List in 4orb
Calcium binding site 1 out of 4 in the Crytal Structure of Mouse Calcineurin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crytal Structure of Mouse Calcineurin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca201

b:48.2
occ:1.00
OE1 B:GLU73 2.8 51.9 1.0
OD1 B:ASP64 2.8 50.9 1.0
O B:GLU68 2.8 78.6 1.0
OD1 B:ASN66 2.9 71.7 1.0
OD1 B:ASP62 2.9 56.4 1.0
OE2 B:GLU73 3.0 51.8 1.0
O B:HOH301 3.0 65.5 1.0
OD2 B:ASP64 3.1 49.3 1.0
CG B:ASN66 3.2 70.6 1.0
CD B:GLU73 3.2 51.0 1.0
CG B:ASP64 3.3 50.2 1.0
C B:GLU68 3.3 80.0 1.0
ND2 B:ASN66 3.3 68.5 1.0
N B:VAL69 3.8 56.8 1.0
CG B:ASP62 3.8 60.0 1.0
CA B:VAL69 3.8 53.2 1.0
OD1 B:ASP70 3.9 63.0 1.0
N B:ASP70 4.0 63.5 1.0
N B:GLU68 4.1 81.2 1.0
CA B:GLU68 4.2 83.2 1.0
N B:ASN66 4.3 68.9 1.0
CB B:ASN66 4.3 70.9 1.0
C B:VAL69 4.4 51.9 1.0
CA B:ASP62 4.4 54.4 1.0
CB B:ASP62 4.5 57.9 1.0
OD2 B:ASP62 4.6 63.6 1.0
CB B:ASP64 4.7 49.4 1.0
N B:GLY67 4.7 66.8 1.0
CA B:ASN66 4.7 70.4 1.0
CG B:GLU73 4.7 49.3 1.0
CB B:GLU68 4.7 87.5 1.0
N B:ASP64 4.8 46.9 1.0
CG B:ASP70 4.9 63.8 1.0
C B:ASP62 4.9 51.4 1.0
N B:GLY65 4.9 59.8 1.0

Calcium binding site 2 out of 4 in 4orb

Go back to Calcium Binding Sites List in 4orb
Calcium binding site 2 out of 4 in the Crytal Structure of Mouse Calcineurin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crytal Structure of Mouse Calcineurin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca202

b:52.6
occ:1.00
O B:TYR105 2.7 57.0 1.0
OE1 B:GLU110 2.8 57.5 1.0
OD1 B:ASP101 2.9 61.7 1.0
OE2 B:GLU110 2.9 54.4 1.0
O B:HOH302 2.9 63.4 1.0
OD1 B:ASP99 2.9 53.6 1.0
OD1 B:ASP103 2.9 65.7 1.0
CD B:GLU110 3.0 57.0 1.0
OD2 B:ASP101 3.2 70.2 1.0
CG B:ASP101 3.2 65.9 1.0
CG B:ASP103 3.3 63.6 1.0
OD2 B:ASP103 3.3 66.3 1.0
C B:TYR105 3.8 58.8 1.0
CG B:ASP99 4.0 53.8 1.0
N B:SER107 4.1 54.0 1.0
CG B:GLU110 4.3 56.9 1.0
N B:ASP101 4.3 61.0 1.0
CB B:SER107 4.4 58.6 1.0
CB B:ASP101 4.4 65.9 1.0
CB B:ASP103 4.5 57.2 1.0
CA B:ILE106 4.5 62.4 1.0
N B:ASP103 4.6 52.6 1.0
N B:TYR105 4.6 62.9 1.0
N B:ILE106 4.7 60.7 1.0
CA B:ASP99 4.7 55.2 1.0
CA B:TYR105 4.7 62.9 1.0
OG B:SER107 4.7 57.2 1.0
C B:ILE106 4.8 63.4 1.0
N B:MET100 4.8 55.1 1.0
CA B:ASP101 4.8 62.7 1.0
OD2 B:ASP99 4.8 53.5 1.0
CA B:SER107 4.9 56.2 1.0
CB B:ASP99 4.9 52.3 1.0
C B:ASP99 4.9 54.7 1.0
CB B:TYR105 4.9 67.9 1.0

Calcium binding site 3 out of 4 in 4orb

Go back to Calcium Binding Sites List in 4orb
Calcium binding site 3 out of 4 in the Crytal Structure of Mouse Calcineurin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crytal Structure of Mouse Calcineurin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca203

b:50.8
occ:1.00
OE1 B:GLU151 2.7 57.2 1.0
O B:ARG146 2.7 63.2 1.0
OD1 B:ASP144 2.8 80.7 1.0
OD1 B:ASP142 2.9 72.2 1.0
OE2 B:GLU151 2.9 58.6 1.0
OD1 B:ASP140 2.9 65.9 1.0
O B:HOH303 3.1 62.3 1.0
CD B:GLU151 3.1 59.4 1.0
OD2 B:ASP142 3.2 71.8 1.0
CG B:ASP144 3.2 81.6 1.0
OD2 B:ASP144 3.2 81.5 1.0
CG B:ASP142 3.2 73.0 1.0
C B:ARG146 3.6 63.2 1.0
CG B:ASP140 3.7 64.4 1.0
N B:SER148 3.9 59.7 1.0
CA B:ILE147 4.0 58.8 1.0
CA B:ASP140 4.2 62.4 1.0
N B:ILE147 4.2 57.6 1.0
CB B:ASP140 4.3 63.0 1.0
CB B:ASP144 4.4 81.4 1.0
CB B:ASP142 4.4 74.0 1.0
N B:ARG146 4.4 66.7 1.0
C B:ILE147 4.4 61.1 1.0
N B:ASP144 4.4 79.8 1.0
N B:ASP142 4.4 68.6 1.0
OD2 B:ASP140 4.5 62.8 1.0
CG B:GLU151 4.6 61.0 1.0
CA B:ARG146 4.6 64.9 1.0
C B:ASP140 4.6 65.1 1.0
OG B:SER148 4.7 61.7 1.0
CB B:SER148 4.7 62.1 1.0
CD1 B:ILE147 4.8 58.6 1.0
CA B:ASP142 4.8 71.8 1.0
CA B:ASP144 4.8 79.9 1.0
N B:GLY145 4.8 66.4 1.0
N B:LYS141 4.9 71.1 1.0
CA B:SER148 4.9 59.8 1.0
N B:GLY143 5.0 58.6 1.0
CG B:ARG146 5.0 68.8 1.0

Calcium binding site 4 out of 4 in 4orb

Go back to Calcium Binding Sites List in 4orb
Calcium binding site 4 out of 4 in the Crytal Structure of Mouse Calcineurin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crytal Structure of Mouse Calcineurin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca204

b:60.0
occ:1.00
O B:SER36 2.8 86.3 1.0
OE1 B:GLU41 2.8 75.0 1.0
OD1 B:ASP32 2.8 0.3 1.0
OG B:SER34 2.9 70.8 1.0
OD1 B:ASP30 2.9 75.7 1.0
OD2 B:ASP32 3.1 0.7 1.0
OE2 B:GLU41 3.1 77.0 1.0
CD B:GLU41 3.2 75.6 1.0
CG B:ASP32 3.3 0.5 1.0
C B:SER36 3.6 83.6 1.0
N B:SER38 3.7 70.8 1.0
CB B:SER34 3.9 74.1 1.0
CA B:LEU37 3.9 72.2 1.0
CG B:ASP30 4.0 75.6 1.0
N B:LEU37 4.1 69.1 1.0
OE2 B:GLU68 4.1 99.7 1.0
C B:LEU37 4.2 73.6 1.0
OE1 B:GLU68 4.3 99.6 1.0
N B:SER36 4.4 85.8 1.0
CG B:GLU41 4.5 74.7 1.0
CD B:GLU68 4.5 97.7 1.0
N B:SER34 4.5 74.9 1.0
OD2 B:ASP30 4.5 72.3 1.0
CB B:SER38 4.5 73.4 1.0
OG B:SER38 4.6 75.0 1.0
CA B:SER36 4.6 82.1 1.0
CA B:SER34 4.7 73.6 1.0
CD1 B:LEU37 4.7 71.4 1.0
CB B:ASP32 4.7 0.7 1.0
CA B:SER38 4.8 69.2 1.0
OG B:SER36 4.8 82.2 1.0
N B:GLY35 5.0 78.2 1.0
CA B:ASP30 5.0 79.3 1.0

Reference:

S.J.Li, L.Ma, J.Wang, C.Lu, J.Wang, J.W.Wu, Z.X.Wang. Cooperative Autoinhibition and Multi-Level Activation Mechanisms of Calcineurin To Be Published.
Page generated: Sat Dec 12 05:02:39 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy