Calcium in PDB 4qeg: Crystal Structure of Domain I10 From Titin (Space Group P41)

All present enzymatic activity of Crystal Structure of Domain I10 From Titin (Space Group P41):
2.7.11.1;

The structure of Crystal Structure of Domain I10 From Titin (Space Group P41), PDB code: 4qeg was solved by J.Bogomolovas, S.Labeit, O.Mayans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.76 / 2.00
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	31.237, 31.237, 93.848, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 23.1

The binding sites of Calcium atom in the Crystal Structure of Domain I10 From Titin (Space Group P41) (pdb code 4qeg). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of Domain I10 From Titin (Space Group P41), PDB code: 4qeg:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Crystal Structure of Domain I10 From Titin (Space Group P41)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Domain I10 From Titin (Space Group P41) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca3001 b:22.9 occ:1.00 O A:HOH3149 2.3 14.5 1.0 O A:HOH3173 2.3 20.8 1.0 O A:GLY2910 2.4 17.1 1.0 O A:HOH3148 2.5 14.6 1.0 O A:HOH3106 2.6 17.1 1.0 C A:GLY2910 3.6 21.0 1.0 CG1 A:VAL2908 4.1 14.1 1.0 CA A:ASN2911 4.2 26.4 1.0 N A:ASN2911 4.3 16.9 1.0 N A:GLY2910 4.5 20.0 1.0 CA A:GLY2910 4.6 23.5 1.0 O A:HOH3218 4.7 18.1 1.0 O A:HOH3140 4.7 29.5 1.0 C A:CYS2909 4.8 17.1 1.0 C A:ASN2911 4.8 25.1 1.0 O A:ASP2912 4.9 20.5 1.0

Calcium binding site 2 out of 3 in the Crystal Structure of Domain I10 From Titin (Space Group P41)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Domain I10 From Titin (Space Group P41) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca3002 b:33.8 occ:1.00 OE2 A:GLU2849 2.4 31.9 1.0 O A:HOH3166 2.6 29.6 1.0 O A:HOH3171 2.7 27.0 1.0 OG1 A:THR2899 2.7 16.6 1.0 OE1 A:GLU2849 2.7 23.4 1.0 CD A:GLU2849 2.9 25.4 1.0 O A:HOH3211 2.9 35.6 1.0 CB A:THR2899 3.8 19.1 1.0 N A:THR2899 4.2 18.4 1.0 CA A:CA3003 4.3 52.2 1.0 CG A:GLU2849 4.4 19.4 1.0 O A:HOH3151 4.5 29.1 1.0 CA A:THR2899 4.6 14.5 1.0 O A:HOH3216 4.7 33.7 1.0 O A:HOH3163 4.8 32.5 1.0 CG2 A:THR2899 4.9 16.8 1.0

Calcium binding site 3 out of 3 in the Crystal Structure of Domain I10 From Titin (Space Group P41)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of Domain I10 From Titin (Space Group P41) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca3003 b:52.2 occ:1.00 O A:HOH3161 2.5 35.1 1.0 O A:HOH3163 2.5 32.5 1.0 O A:HOH3154 2.5 18.7 1.0 OE1 A:GLU2849 2.6 23.4 1.0 O A:HOH3216 2.6 33.7 1.0 O A:HOH3139 2.6 29.2 1.0 O A:HOH3211 3.3 35.6 1.0 CD A:GLU2849 3.7 25.4 1.0 CB A:GLU2849 4.0 11.1 1.0 O A:HOH3214 4.3 33.3 1.0 CA A:CA3002 4.3 33.8 1.0 CG A:GLU2849 4.4 19.4 1.0 O A:HOH3151 4.6 29.1 1.0 CG2 A:THR2921 4.7 21.0 1.0 OE2 A:GLU2849 4.7 31.9 1.0

J.Bogomolovas, S.Labeit, B.Anderson, R.Williams, S.Lange, B.Simon, M.M.Khan, R.Rudolf, B.Bullard, D.J.Rigden, H.Granzier, S.Labiet, O.Mayans. Exploration of the Pathological Potential of Isolated Msnps in Titin: the Cardiomyopathy-Linked Mutation T2580I Open Biology 2016.
ISSN: ESSN 2046-2441