Calcium in PDB 4qn5: Neuraminidase N5 Binds Lsta at the Second Sia Binding Site

The structure of Neuraminidase N5 Binds Lsta at the Second Sia Binding Site, PDB code: 4qn5 was solved by X.Sun, Q.Li, Y.Wu, Y.Liu, J.Qi, C.J.Vavricka, G.F.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.96 / 1.70
Space group	P 4
Cell size a, b, c (Å), α, β, γ (°)	112.251, 112.251, 66.756, 90.00, 90.00, 90.00
R / Rfree (%)	11.7 / 17.6

The binding sites of Calcium atom in the Neuraminidase N5 Binds Lsta at the Second Sia Binding Site (pdb code 4qn5). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Neuraminidase N5 Binds Lsta at the Second Sia Binding Site, PDB code: 4qn5:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Neuraminidase N5 Binds Lsta at the Second Sia Binding Site


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Neuraminidase N5 Binds Lsta at the Second Sia Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca601 b:27.0 occ:1.00 O A:ASP213 2.4 5.4 1.0 OD2 A:ASP243 2.4 10.2 1.0 O A:TYR268 2.4 4.4 1.0 O A:GLY217 2.5 8.0 1.0 O A:HOH703 2.5 6.8 1.0 O A:HOH701 2.5 7.0 1.0 CG A:ASP243 3.6 14.8 1.0 C A:ASP213 3.6 8.9 1.0 C A:TYR268 3.6 5.8 1.0 C A:GLY217 3.6 12.6 1.0 CA A:GLY269 3.9 9.7 1.0 O A:HOH726 4.0 11.2 1.0 N A:GLY269 4.2 5.0 1.0 O A:THR265 4.3 14.0 1.0 CA A:MET218 4.3 8.4 1.0 CA A:ASN214 4.3 4.8 1.0 O A:HOH728 4.4 10.4 1.0 N A:MET218 4.4 8.9 1.0 OD1 A:ASP243 4.4 9.8 1.0 CB A:ASP243 4.4 9.7 1.0 N A:ASN214 4.4 5.9 1.0 OD1 A:ASP213 4.6 11.4 1.0 CA A:ASP213 4.6 7.3 1.0 CB A:ASP213 4.6 7.5 1.0 N A:GLY217 4.6 8.4 1.0 CA A:GLY217 4.6 13.0 1.0 N A:TYR268 4.7 8.6 1.0 C A:ASN214 4.7 8.7 1.0 N A:TRP215 4.8 8.3 1.0 CA A:TYR268 4.8 7.8 1.0 N A:ASP213 4.8 7.6 1.0 O A:PRO245 5.0 14.8 1.0

Calcium binding site 2 out of 2 in the Neuraminidase N5 Binds Lsta at the Second Sia Binding Site


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Neuraminidase N5 Binds Lsta at the Second Sia Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca601 b:6.5 occ:1.00 O B:ASP213 2.4 7.7 1.0 O B:TYR268 2.4 6.1 1.0 OD2 B:ASP243 2.4 11.2 1.0 O B:GLY217 2.5 7.8 1.0 O B:HOH709 2.5 7.6 1.0 O B:HOH703 2.5 9.4 1.0 CG B:ASP243 3.6 13.9 1.0 C B:TYR268 3.6 11.5 1.0 C B:GLY217 3.6 11.6 1.0 C B:ASP213 3.6 12.5 1.0 CA B:GLY269 3.9 4.5 1.0 O B:HOH740 4.1 11.4 1.0 N B:GLY269 4.2 5.5 1.0 O B:THR265 4.3 12.4 1.0 CA B:MET218 4.3 9.4 1.0 O B:HOH720 4.3 10.1 1.0 CA B:ASN214 4.3 9.1 1.0 N B:MET218 4.4 8.3 1.0 OD1 B:ASP243 4.4 6.9 1.0 CB B:ASP243 4.4 14.6 1.0 N B:ASN214 4.4 7.7 1.0 OD1 B:ASP213 4.5 10.2 1.0 N B:GLY217 4.6 9.6 1.0 CA B:GLY217 4.6 11.3 1.0 CA B:ASP213 4.6 7.6 1.0 CB B:ASP213 4.7 11.1 1.0 N B:TYR268 4.7 8.3 1.0 C B:ASN214 4.7 8.8 1.0 N B:TRP215 4.8 7.2 1.0 CA B:TYR268 4.8 13.1 1.0 N B:ASP213 4.8 6.3 1.0 O B:PRO245 5.0 10.9 1.0

X.Sun, Q.Li, Y.Wu, M.Wang, Y.Liu, J.Qi, C.J.Vavricka, G.F.Gao. Structure of Influenza Virus N7: the Last Piece of the Neuraminidase "Jigsaw" Puzzle J.Virol. 2014.
ISSN: ESSN 1098-5514
PubMed: 24899180
DOI: 10.1128/JVI.00805-14