Calcium in PDB 4usl: The X-Ray Structure of Calcium Bound Human Sorcin

The structure of The X-Ray Structure of Calcium Bound Human Sorcin, PDB code: 4usl was solved by A.Ilari, A.Fiorillo, G.Colotti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.34 / 1.65
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	52.369, 111.580, 60.479, 90.00, 90.00, 90.00
R / Rfree (%)	19.187 / 22.135

The binding sites of Calcium atom in the The X-Ray Structure of Calcium Bound Human Sorcin (pdb code 4usl). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the The X-Ray Structure of Calcium Bound Human Sorcin, PDB code: 4usl:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the The X-Ray Structure of Calcium Bound Human Sorcin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of The X-Ray Structure of Calcium Bound Human Sorcin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1199 b:25.5 occ:1.00 O A:HOH2076 2.3 31.1 1.0 O A:THR119 2.3 22.3 1.0 OD1 A:ASP113 2.3 30.5 1.0 OD1 A:ASP115 2.4 28.6 1.0 OG A:SER117 2.4 32.1 1.0 OE1 A:GLU124 2.5 23.1 1.0 OE2 A:GLU124 2.6 24.2 1.0 CD A:GLU124 3.0 22.7 1.0 CG A:ASP115 3.4 33.1 1.0 CG A:ASP113 3.4 29.9 1.0 C A:THR119 3.5 25.2 1.0 CB A:SER117 3.6 31.9 1.0 OD2 A:ASP115 3.9 34.3 1.0 N A:SER117 4.0 31.1 1.0 CA A:ASP113 4.1 28.9 1.0 CB A:ASP113 4.3 28.3 1.0 OD2 A:ASP113 4.3 32.6 1.0 OG1 A:THR119 4.3 27.7 1.0 CA A:SER117 4.3 30.9 1.0 N A:VAL120 4.3 23.7 1.0 CA A:VAL120 4.4 22.5 1.0 N A:ASP121 4.4 22.3 1.0 OD2 A:ASP121 4.4 26.4 1.0 C A:ASP113 4.4 31.4 1.0 N A:THR119 4.4 27.6 1.0 CG A:GLU124 4.5 22.0 1.0 N A:ASP115 4.5 34.5 1.0 CA A:THR119 4.5 26.3 1.0 CB A:ASP115 4.7 34.5 1.0 N A:ARG116 4.7 36.6 1.0 N A:THR114 4.8 31.4 1.0 O A:HOH2074 4.8 44.7 1.0 C A:VAL120 4.8 23.2 1.0 O A:ASP113 4.8 31.6 1.0 C A:ASP115 4.9 37.2 1.0 CA A:ASP115 4.9 34.5 1.0 CG A:ASP121 4.9 24.1 1.0 C A:SER117 5.0 30.8 1.0 N A:GLY118 5.0 31.1 1.0

Calcium binding site 2 out of 3 in the The X-Ray Structure of Calcium Bound Human Sorcin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of The X-Ray Structure of Calcium Bound Human Sorcin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1200 b:18.7 occ:1.00 O A:GLN48 2.3 17.3 1.0 O A:ALA43 2.3 18.3 1.0 OD1 A:ASP46 2.4 23.4 1.0 O A:HOH2016 2.4 23.8 1.0 O A:HOH2010 2.5 21.2 1.0 OE1 A:GLU53 2.5 18.2 1.0 OE2 A:GLU53 2.6 18.8 1.0 CD A:GLU53 2.9 18.8 1.0 CG A:ASP46 3.3 27.6 1.0 C A:ALA43 3.5 17.9 1.0 C A:GLN48 3.5 18.6 1.0 OD2 A:ASP46 3.7 29.6 1.0 CA A:ALA43 4.1 16.8 1.0 N A:GLN48 4.2 19.4 1.0 CG A:GLU53 4.4 17.0 1.0 CA A:GLN48 4.4 19.8 1.0 N A:ILE49 4.5 17.0 1.0 N A:ASP46 4.5 29.6 1.0 CA A:ILE49 4.5 16.4 1.0 OD2 A:ASP50 4.5 19.9 1.0 N A:GLY44 4.5 20.2 1.0 CB A:ASP46 4.6 27.3 1.0 N A:ASP50 4.6 17.1 1.0 CB A:ALA43 4.7 15.8 1.0 O A:HOH2009 4.7 33.3 1.0 C A:GLY44 4.7 23.5 1.0 N A:GLY47 4.8 22.9 1.0 CA A:GLY44 4.8 22.0 1.0 CA A:ASP46 4.9 27.6 1.0 N A:GLN45 4.9 28.3 1.0 O A:VAL42 4.9 17.9 1.0 CB A:GLN48 4.9 20.8 1.0 C A:ILE49 5.0 16.1 1.0

Calcium binding site 3 out of 3 in the The X-Ray Structure of Calcium Bound Human Sorcin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of The X-Ray Structure of Calcium Bound Human Sorcin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1201 b:20.4 occ:1.00 OD1 A:ASP83 2.3 22.2 1.0 OD1 A:ASP85 2.4 24.1 1.0 O A:HOH2019 2.4 22.1 1.0 O A:THR89 2.4 18.5 1.0 OE1 A:GLU94 2.5 19.9 1.0 OG A:SER87 2.6 22.8 1.0 OE2 A:GLU94 2.6 19.9 1.0 CD A:GLU94 3.0 19.2 1.0 CG A:ASP85 3.3 25.2 1.0 CG A:ASP83 3.6 20.4 1.0 OD2 A:ASP85 3.6 27.8 1.0 CB A:SER87 3.6 24.6 1.0 C A:THR89 3.6 20.3 1.0 N A:SER87 4.3 26.9 1.0 N A:ARG84 4.3 19.2 1.0 N A:GLY91 4.3 17.5 1.0 OG1 A:THR89 4.3 22.5 1.0 N A:THR89 4.3 21.6 1.0 OD2 A:ASP83 4.3 24.6 1.0 CA A:ASP83 4.4 18.4 1.0 CA A:SER87 4.4 24.4 1.0 O A:HOH2057 4.4 31.3 1.0 CA A:MET90 4.5 18.4 1.0 CG A:GLU94 4.5 18.8 1.0 N A:ASP85 4.5 23.0 1.0 N A:MET90 4.5 18.8 1.0 NE2 A:GLN48 4.5 22.5 1.0 O A:HOH2048 4.5 19.8 1.0 CB A:ASP83 4.6 20.2 1.0 CA A:THR89 4.6 21.3 1.0 CB A:ASP85 4.7 24.5 1.0 N A:GLY88 4.7 23.2 1.0 C A:MET90 4.8 18.9 1.0 C A:SER87 4.8 25.5 1.0 C A:ASP83 4.9 19.0 1.0

A.Ilari, A.Fiorillo, E.Poser, V.S.Lalioti, G.N.Sundell, Y.Ivarsson, I.Genovese, G.Colotti. Structural Basis of Sorcin-Mediated Calcium-Dependent Signal Transduction. Sci.Rep. V. 5 16828 2015.
ISSN: ISSN 2045-2322
PubMed: 26577048
DOI: 10.1038/SREP16828