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Calcium in PDB 4ux8: Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association

Enzymatic activity of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association

All present enzymatic activity of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association:
2.7.10.1;

Calcium Binding Sites:

The binding sites of Calcium atom in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association (pdb code 4ux8). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 6 binding sites of Calcium where determined in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association, PDB code: 4ux8:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6;

Calcium binding site 1 out of 6 in 4ux8

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Calcium binding site 1 out of 6 in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1603

b:10.5
occ:1.00
O A:GLU265 2.3 30.5 1.0
OD1 A:ASP267 2.5 10.1 1.0
OE2 A:GLU178 2.6 40.2 1.0
OD2 A:ASP264 2.7 47.1 1.0
OD1 A:ASP264 2.9 47.1 1.0
CG A:ASP264 3.0 47.1 1.0
C A:GLU265 3.5 30.5 1.0
N A:GLU265 3.6 30.5 1.0
OD1 A:ASP302 3.6 93.3 1.0
CG A:ASP267 3.7 10.1 1.0
CD A:GLU178 3.8 39.3 1.0
CA A:GLU265 4.1 30.5 1.0
N A:ASP267 4.2 48.2 1.0
CG A:ASP302 4.2 93.3 1.0
CB A:ASP267 4.4 10.1 1.0
CB A:ASP264 4.4 47.1 1.0
CB A:ASP302 4.4 93.3 1.0
C A:ASP264 4.6 43.1 1.0
OD2 A:ASP267 4.6 10.1 1.0
N A:ASP266 4.6 34.3 1.0
OE1 A:GLU178 4.6 39.4 1.0
CA A:ASP264 4.6 43.1 1.0
CG A:GLU178 4.8 40.6 1.0
CB A:ARG231 4.8 47.0 1.0
CA A:CA1604 4.8 12.9 1.0
CB A:GLU265 4.8 20.0 1.0
CD A:ARG231 4.8 50.1 1.0
CA A:ASP302 4.8 93.3 1.0
N A:VAL303 4.8 58.3 1.0
CA A:ASP267 4.9 48.2 1.0
CA A:ASP266 4.9 34.3 1.0

Calcium binding site 2 out of 6 in 4ux8

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Calcium binding site 2 out of 6 in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1604

b:12.9
occ:1.00
OD1 A:ASP230 2.0 54.0 1.0
OD2 A:ASP267 2.4 10.1 1.0
CG A:ASP267 2.6 10.1 1.0
CB A:GLU232 2.7 50.5 1.0
CG A:ASP230 2.8 52.0 1.0
N A:GLU232 2.9 49.3 1.0
CB A:ASP267 3.1 10.1 1.0
OE1 A:GLU178 3.2 39.4 1.0
OD1 A:ASP267 3.2 10.1 1.0
OD2 A:ASP230 3.2 57.2 1.0
CA A:GLU232 3.4 49.9 1.0
N A:ARG231 3.8 45.5 1.0
CD A:GLU178 3.8 39.3 1.0
OE2 A:GLU178 3.9 40.2 1.0
C A:ASP230 4.0 45.0 1.0
CB A:ASP230 4.0 47.5 1.0
C A:ARG231 4.1 49.2 1.0
CA A:ASP230 4.2 46.8 1.0
C A:GLU232 4.4 50.2 1.0
CA A:ARG231 4.4 46.9 1.0
N A:GLN233 4.5 49.1 1.0
O A:ASP230 4.6 44.7 1.0
CA A:ASP267 4.6 48.2 1.0
CA A:CA1603 4.8 10.5 1.0
CB A:ARG231 4.9 47.0 1.0

Calcium binding site 3 out of 6 in 4ux8

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Calcium binding site 3 out of 6 in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1605

b:10.5
occ:1.00
OD2 A:ASP302 1.9 93.3 1.0
O A:SER268 2.3 65.3 1.0
NH1 A:ARG360 2.6 0.5 1.0
OD1 A:ASP266 2.6 20.0 1.0
O A:GLY308 2.8 49.4 1.0
OD2 A:ASP300 3.0 92.6 1.0
CG A:ASP302 3.0 93.3 1.0
C A:GLY308 3.2 49.4 1.0
C A:SER268 3.3 65.3 1.0
OG A:SER268 3.3 20.0 1.0
OD1 A:ASP300 3.6 92.6 1.0
CA A:GLY308 3.6 49.4 1.0
CG A:ASP300 3.6 92.6 1.0
CG A:ASP266 3.6 20.0 1.0
CZ A:ARG360 3.7 0.5 1.0
CB A:ASP302 3.8 93.3 1.0
N A:GLU309 4.0 0.8 1.0
CA A:SER268 4.0 65.3 1.0
OD1 A:ASP302 4.0 93.3 1.0
N A:SER268 4.2 65.3 1.0
OD2 A:ASP266 4.2 20.0 1.0
CB A:SER268 4.2 20.0 1.0
N A:ALA269 4.3 45.7 1.0
NH2 A:ARG360 4.3 0.5 1.0
CA A:GLU309 4.4 0.8 1.0
CA A:ASP266 4.4 34.3 1.0
CB A:ASP266 4.5 20.0 1.0
CA A:ALA269 4.6 45.7 1.0
C A:ASP266 4.7 34.3 1.0
NE A:ARG360 4.7 0.5 1.0
CD A:ARG360 4.8 0.5 1.0
O A:ASP266 4.8 34.3 1.0
CB A:ASP300 4.9 92.6 1.0
C A:ALA269 4.9 45.7 1.0
N A:GLY308 5.0 49.4 1.0

Calcium binding site 4 out of 6 in 4ux8

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Calcium binding site 4 out of 6 in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca1603

b:10.5
occ:1.00
O B:GLU265 2.3 30.5 1.0
OD1 B:ASP267 2.5 10.1 1.0
OE2 B:GLU178 2.6 40.2 1.0
OD2 B:ASP264 2.7 47.1 1.0
OD1 B:ASP264 2.9 47.1 1.0
CG B:ASP264 3.0 47.1 1.0
C B:GLU265 3.5 30.5 1.0
N B:GLU265 3.6 30.5 1.0
OD1 B:ASP302 3.6 93.3 1.0
CG B:ASP267 3.7 10.1 1.0
CD B:GLU178 3.8 39.3 1.0
CA B:GLU265 4.1 30.5 1.0
N B:ASP267 4.2 48.2 1.0
CG B:ASP302 4.2 93.3 1.0
CB B:ASP267 4.4 10.1 1.0
CB B:ASP264 4.4 47.1 1.0
CB B:ASP302 4.4 93.3 1.0
C B:ASP264 4.6 43.1 1.0
OD2 B:ASP267 4.6 10.1 1.0
N B:ASP266 4.6 34.3 1.0
OE1 B:GLU178 4.6 39.4 1.0
CA B:ASP264 4.6 43.1 1.0
CG B:GLU178 4.8 40.6 1.0
CB B:ARG231 4.8 47.0 1.0
CA B:CA1604 4.8 12.9 1.0
CB B:GLU265 4.8 20.0 1.0
CD B:ARG231 4.8 50.1 1.0
CA B:ASP302 4.8 93.3 1.0
N B:VAL303 4.8 58.3 1.0
CA B:ASP267 4.9 48.2 1.0
CA B:ASP266 4.9 34.3 1.0

Calcium binding site 5 out of 6 in 4ux8

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Calcium binding site 5 out of 6 in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca1604

b:12.9
occ:1.00
OD1 B:ASP230 2.0 54.0 1.0
OD2 B:ASP267 2.4 10.1 1.0
CG B:ASP267 2.6 10.1 1.0
CB B:GLU232 2.7 50.5 1.0
CG B:ASP230 2.8 52.0 1.0
N B:GLU232 2.9 49.3 1.0
CB B:ASP267 3.1 10.1 1.0
OE1 B:GLU178 3.2 39.4 1.0
OD1 B:ASP267 3.2 10.1 1.0
OD2 B:ASP230 3.2 57.2 1.0
CA B:GLU232 3.4 49.9 1.0
N B:ARG231 3.8 45.5 1.0
CD B:GLU178 3.8 39.3 1.0
OE2 B:GLU178 3.9 40.2 1.0
C B:ASP230 4.0 45.0 1.0
CB B:ASP230 4.0 47.5 1.0
C B:ARG231 4.1 49.2 1.0
CA B:ASP230 4.2 46.8 1.0
CA B:ARG231 4.4 46.9 1.0
C B:GLU232 4.4 50.2 1.0
N B:GLN233 4.5 49.1 1.0
O B:ASP230 4.6 44.7 1.0
CA B:ASP267 4.6 48.2 1.0
CA B:CA1603 4.8 10.5 1.0
CB B:ARG231 4.9 47.0 1.0

Calcium binding site 6 out of 6 in 4ux8

Go back to Calcium Binding Sites List in 4ux8
Calcium binding site 6 out of 6 in the Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca1605

b:10.5
occ:1.00
OD2 B:ASP302 1.9 93.3 1.0
O B:SER268 2.3 65.3 1.0
NH1 B:ARG360 2.6 0.5 1.0
OD1 B:ASP266 2.6 20.0 1.0
O B:GLY308 2.8 49.4 1.0
OD2 B:ASP300 3.0 92.6 1.0
CG B:ASP302 3.0 93.3 1.0
C B:GLY308 3.2 49.4 1.0
C B:SER268 3.3 65.3 1.0
OG B:SER268 3.3 20.0 1.0
OD1 B:ASP300 3.6 92.6 1.0
CA B:GLY308 3.6 49.4 1.0
CG B:ASP300 3.6 92.6 1.0
CG B:ASP266 3.6 20.0 1.0
CZ B:ARG360 3.7 0.5 1.0
CB B:ASP302 3.8 93.3 1.0
N B:GLU309 4.0 0.8 1.0
CA B:SER268 4.0 65.3 1.0
OD1 B:ASP302 4.0 93.3 1.0
N B:SER268 4.2 65.3 1.0
OD2 B:ASP266 4.2 20.0 1.0
CB B:SER268 4.2 20.0 1.0
N B:ALA269 4.3 45.7 1.0
NH2 B:ARG360 4.3 0.5 1.0
CA B:GLU309 4.4 0.8 1.0
CA B:ASP266 4.4 34.3 1.0
CB B:ASP266 4.5 20.0 1.0
CA B:ALA269 4.6 45.7 1.0
C B:ASP266 4.7 34.3 1.0
NE B:ARG360 4.7 0.5 1.0
CD B:ARG360 4.8 0.5 1.0
O B:ASP266 4.8 34.3 1.0
CB B:ASP300 4.9 92.6 1.0
C B:ALA269 4.9 45.7 1.0
N B:GLY308 5.0 49.4 1.0

Reference:

K.M.Goodman, S.Kjaer, F.Beuron, P.P.Knowles, A.Nawrotek, E.M.Burns, A.G.Purkiss, R.George, M.Santoro, E.P.Morris, N.Q.Mcdonald. Ret Recognition of Gdnf-GFRALPHA1 Ligand By A Composite Binding Site Promotes Membrane-Proximal Self-Association. Cell Rep. V. 8 1894 2014.
ISSN: ISSN 2211-1247
PubMed: 25242331
DOI: 10.1016/J.CELREP.2014.08.040
Page generated: Sun Jul 14 13:51:50 2024

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