Calcium in PDB 4wff: Human Traak K+ Channel in A K+ Bound Nonconductive Conformation

The structure of Human Traak K+ Channel in A K+ Bound Nonconductive Conformation, PDB code: 4wff was solved by S.G.Brohawn, R.Mackinnon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.10 / 2.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	80.666, 138.891, 96.531, 90.00, 95.15, 90.00
R / Rfree (%)	21.3 / 24.5

The structure of Human Traak K+ Channel in A K+ Bound Nonconductive Conformation also contains other interesting chemical elements:

Potassium

(K)

5 atoms

The binding sites of Calcium atom in the Human Traak K+ Channel in A K+ Bound Nonconductive Conformation (pdb code 4wff). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Human Traak K+ Channel in A K+ Bound Nonconductive Conformation, PDB code: 4wff:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Human Traak K+ Channel in A K+ Bound Nonconductive Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Traak K+ Channel in A K+ Bound Nonconductive Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca304 b:0.9 occ:1.00 OD1 A:ASP249 2.3 0.5 1.0 OD2 A:ASP115 2.4 0.5 1.0 O A:SER112 2.5 81.8 1.0 OG A:SER118 2.6 80.4 1.0 OD1 A:ASP115 2.8 0.2 1.0 CG A:ASP115 2.9 99.1 1.0 CG A:ASP249 3.0 0.4 1.0 OD2 A:ASP249 3.0 0.1 1.0 C A:SER112 3.6 86.5 1.0 CB A:SER118 3.8 80.5 1.0 N A:SER112 4.1 0.6 1.0 O A:SER110 4.2 0.5 1.0 CA A:SER112 4.3 97.9 1.0 CB A:ASP249 4.4 0.7 1.0 CB A:ASP115 4.4 96.0 1.0 N A:ALA113 4.6 73.6 1.0 N A:SER118 4.6 86.5 1.0 O A:ALA248 4.6 1.0 1.0 C A:HIS111 4.7 0.9 1.0 CA A:SER118 4.8 81.8 1.0 CA A:ALA113 4.8 69.3 1.0 CA A:ASP249 4.9 0.8 1.0 C A:SER110 4.9 0.0 1.0 CB A:SER112 4.9 97.5 1.0 CD A:PRO250 4.9 0.2 1.0

Calcium binding site 2 out of 3 in the Human Traak K+ Channel in A K+ Bound Nonconductive Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Traak K+ Channel in A K+ Bound Nonconductive Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca305 b:93.2 occ:1.00 O A:GLY98 2.3 77.0 1.0 O A:HOH416 2.5 88.6 1.0 OE2 B:GLU58 2.8 76.3 1.0 OD2 A:ASP100 2.8 0.8 1.0 O B:HOH414 2.9 79.1 1.0 O A:HIS111 3.5 0.9 1.0 CG A:ASP100 3.5 98.3 1.0 C A:GLY98 3.5 66.8 1.0 CD B:GLU58 3.6 72.7 1.0 CG B:GLU58 3.9 69.5 1.0 CB A:ASP100 4.2 87.9 1.0 C A:ALA99 4.2 65.2 1.0 N A:ASP100 4.2 71.1 1.0 OD1 A:ASP100 4.2 0.9 1.0 CA A:ALA99 4.3 66.4 1.0 N A:ALA113 4.4 73.6 1.0 OE1 B:GLN62 4.4 69.0 1.0 N A:ALA99 4.4 65.2 1.0 CA A:GLY98 4.5 67.2 1.0 C A:HIS111 4.6 0.9 1.0 O A:ALA99 4.6 60.5 1.0 CB A:ALA113 4.6 65.8 1.0 OE1 B:GLU58 4.7 75.8 1.0 CA A:SER112 4.7 97.9 1.0 CA A:ASP100 4.7 79.8 1.0

Calcium binding site 3 out of 3 in the Human Traak K+ Channel in A K+ Bound Nonconductive Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Human Traak K+ Channel in A K+ Bound Nonconductive Conformation within 5.0Å range: probe atom residue distance (Å) B Occ G:Ca301 b:0.8 occ:1.00 OE1 G:GLU10 2.1 89.1 1.0 O G:HOH406 2.5 81.8 1.0 CD G:GLU10 2.8 0.1 1.0 O G:LYS19 2.8 72.0 1.0 OE2 G:GLU10 2.8 0.3 1.0 C G:LYS19 4.0 68.6 1.0 CG G:GLU10 4.2 94.1 1.0 N G:LYS19 4.5 68.6 1.0 CA G:LYS19 4.7 67.2 1.0 O G:HOH402 4.9 62.7 1.0 CB G:LYS19 4.9 71.5 1.0 N G:THR20 5.0 70.2 1.0

S.G.Brohawn, E.B.Campbell, R.Mackinnon. Physical Mechanism For Gating and Mechanosensitivity of the Human Traak K+ Channel Nature 2014.
ISSN: ESSN 1476-4687