Calcium in PDB 4xlw: Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
Protein crystallography data
The structure of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2), PDB code: 4xlw
was solved by
V.C.Luca,
K.M.Jude,
K.C.Garcia,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
84.06 /
3.39
|
|
Space group
|
P 1 21 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
84.560,
95.570,
122.900,
90.00,
96.21,
90.00
|
|
R / Rfree (%)
|
25.7 /
31
|
Calcium Binding Sites:
The binding sites of Calcium atom in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
(pdb code 4xlw). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 10 binding sites of Calcium where determined in the
Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2), PDB code: 4xlw:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Calcium binding site 1 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 1 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca601
b:0.4
occ:1.00
|
O
|
A:THR432
|
2.2
|
0.3
|
1.0
|
|
N
|
A:GLY434
|
2.3
|
0.9
|
1.0
|
|
N
|
A:SER435
|
2.3
|
0.4
|
1.0
|
|
C
|
A:LEU433
|
2.3
|
0.3
|
1.0
|
|
O
|
A:SER435
|
2.5
|
0.1
|
1.0
|
|
CA
|
A:LEU433
|
2.5
|
0.6
|
1.0
|
|
C
|
A:THR432
|
2.6
|
0.7
|
1.0
|
|
OE1
|
A:GLU415
|
2.7
|
0.6
|
1.0
|
|
OD2
|
A:ASP414
|
2.7
|
1.0
|
1.0
|
|
OD1
|
A:ASN431
|
2.7
|
1.0
|
1.0
|
|
N
|
A:LEU433
|
2.7
|
0.0
|
1.0
|
|
C
|
A:GLY434
|
3.0
|
0.3
|
1.0
|
|
CA
|
A:GLY434
|
3.1
|
1.0
|
1.0
|
|
O
|
A:LEU433
|
3.1
|
0.6
|
1.0
|
|
CA
|
A:SER435
|
3.2
|
0.5
|
1.0
|
|
C
|
A:SER435
|
3.2
|
0.5
|
1.0
|
|
CA
|
A:THR432
|
3.8
|
0.4
|
1.0
|
|
CG
|
A:ASN431
|
3.8
|
0.1
|
1.0
|
|
CD
|
A:GLU415
|
3.9
|
0.6
|
1.0
|
|
CG
|
A:ASP414
|
3.9
|
0.2
|
1.0
|
|
N
|
A:THR432
|
4.0
|
0.5
|
1.0
|
|
CB
|
A:LEU433
|
4.0
|
0.3
|
1.0
|
|
O
|
A:GLY434
|
4.2
|
0.6
|
1.0
|
|
CB
|
A:THR432
|
4.4
|
0.9
|
1.0
|
|
ND2
|
A:ASN431
|
4.4
|
0.2
|
1.0
|
|
OE2
|
A:GLU415
|
4.4
|
0.1
|
1.0
|
|
CB
|
A:SER435
|
4.4
|
0.0
|
1.0
|
|
N
|
A:PHE436
|
4.5
|
0.6
|
1.0
|
|
OD1
|
A:ASP414
|
4.7
|
0.4
|
1.0
|
|
C
|
A:ASN431
|
4.8
|
0.9
|
1.0
|
|
CB
|
A:ASP414
|
4.9
|
0.8
|
1.0
|
|
CG
|
A:LEU433
|
4.9
|
0.3
|
1.0
|
|
CG
|
A:GLU415
|
5.0
|
0.5
|
1.0
|
|
Calcium binding site 2 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 2 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca602
b:0.1
occ:1.00
|
OD2
|
A:ASP469
|
2.4
|
0.5
|
1.0
|
|
OD1
|
A:ASP469
|
2.4
|
0.7
|
1.0
|
|
OD1
|
A:ASP452
|
2.4
|
0.9
|
1.0
|
|
O
|
A:GLN470
|
2.5
|
0.7
|
1.0
|
|
OE1
|
A:GLU455
|
2.5
|
0.6
|
1.0
|
|
O
|
A:VAL453
|
2.5
|
0.1
|
1.0
|
|
OD2
|
A:ASP452
|
2.5
|
0.3
|
1.0
|
|
CG
|
A:ASP469
|
2.7
|
0.5
|
1.0
|
|
CG
|
A:ASP452
|
2.8
|
0.2
|
1.0
|
|
CD
|
A:GLU455
|
3.5
|
0.9
|
1.0
|
|
C
|
A:GLN470
|
3.5
|
1.0
|
1.0
|
|
C
|
A:VAL453
|
3.7
|
0.0
|
1.0
|
|
OE2
|
A:GLU455
|
3.7
|
0.8
|
1.0
|
|
CB
|
A:ASP469
|
4.1
|
0.0
|
1.0
|
|
C
|
A:ASP469
|
4.2
|
0.1
|
1.0
|
|
N
|
A:GLN470
|
4.2
|
0.9
|
1.0
|
|
CB
|
A:ASP452
|
4.2
|
0.2
|
1.0
|
|
O
|
A:ASP469
|
4.3
|
0.9
|
1.0
|
|
N
|
A:ILE471
|
4.3
|
0.4
|
1.0
|
|
CA
|
A:GLN470
|
4.4
|
0.1
|
1.0
|
|
CA
|
A:ASN454
|
4.4
|
0.6
|
1.0
|
|
CA
|
A:ILE471
|
4.4
|
0.8
|
1.0
|
|
N
|
A:GLU455
|
4.4
|
0.8
|
1.0
|
|
N
|
A:VAL453
|
4.4
|
0.3
|
1.0
|
|
N
|
A:ASN454
|
4.4
|
0.4
|
1.0
|
|
OG1
|
B:THR110
|
4.5
|
0.5
|
1.0
|
|
C
|
A:ASP452
|
4.5
|
0.8
|
1.0
|
|
CA
|
A:ASP469
|
4.7
|
0.3
|
1.0
|
|
CA
|
A:VAL453
|
4.7
|
0.0
|
1.0
|
|
N
|
A:GLY472
|
4.7
|
0.4
|
1.0
|
|
CG
|
A:GLU455
|
4.8
|
0.9
|
1.0
|
|
CA
|
A:ASP452
|
4.8
|
1.0
|
1.0
|
|
O
|
A:ASP452
|
4.9
|
0.7
|
1.0
|
|
C
|
A:ASN454
|
4.9
|
0.1
|
1.0
|
|
O
|
A:GLY443
|
4.9
|
0.4
|
1.0
|
|
Calcium binding site 3 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 3 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca603
b:0.4
occ:1.00
|
OE1
|
A:GLU493
|
2.4
|
0.4
|
1.0
|
|
OD1
|
A:ASP507
|
2.4
|
0.5
|
1.0
|
|
OD2
|
A:ASP507
|
2.4
|
0.2
|
1.0
|
|
OE2
|
A:GLU493
|
2.4
|
0.3
|
1.0
|
|
O
|
A:THR491
|
2.4
|
0.9
|
1.0
|
|
OD1
|
A:ASN490
|
2.4
|
0.9
|
1.0
|
|
O
|
A:LYS508
|
2.7
|
0.5
|
1.0
|
|
CD
|
A:GLU493
|
2.7
|
0.4
|
1.0
|
|
CG
|
A:ASP507
|
2.7
|
0.2
|
1.0
|
|
C
|
A:THR491
|
3.5
|
0.3
|
1.0
|
|
C
|
A:LYS508
|
3.5
|
0.6
|
1.0
|
|
CG
|
A:ASN490
|
3.6
|
0.5
|
1.0
|
|
N
|
A:LYS508
|
4.2
|
0.4
|
1.0
|
|
CG
|
A:GLU493
|
4.2
|
0.9
|
1.0
|
|
ND2
|
A:ASN490
|
4.2
|
0.2
|
1.0
|
|
CA
|
A:ILE509
|
4.2
|
0.3
|
1.0
|
|
N
|
A:ILE509
|
4.2
|
0.9
|
1.0
|
|
CB
|
A:ASP507
|
4.2
|
0.6
|
1.0
|
|
N
|
A:THR491
|
4.3
|
0.3
|
1.0
|
|
N
|
A:GLU493
|
4.3
|
0.2
|
1.0
|
|
N
|
A:ASP492
|
4.3
|
0.7
|
1.0
|
|
CA
|
A:ASP492
|
4.4
|
0.1
|
1.0
|
|
CA
|
A:THR491
|
4.4
|
0.5
|
1.0
|
|
C
|
A:ASN490
|
4.4
|
0.4
|
1.0
|
|
CA
|
A:LYS508
|
4.5
|
0.5
|
1.0
|
|
O
|
A:ASN490
|
4.6
|
0.3
|
1.0
|
|
C
|
A:ASP507
|
4.7
|
0.3
|
1.0
|
|
N
|
A:ASN510
|
4.7
|
0.7
|
1.0
|
|
CB
|
A:ASN490
|
4.8
|
0.1
|
1.0
|
|
C
|
A:ASP492
|
4.9
|
0.8
|
1.0
|
|
O
|
A:GLY481
|
4.9
|
1.0
|
1.0
|
|
CB
|
A:GLU493
|
4.9
|
0.6
|
1.0
|
|
CA
|
A:ASP507
|
4.9
|
0.1
|
1.0
|
|
CB
|
A:THR491
|
5.0
|
0.2
|
1.0
|
|
Calcium binding site 4 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 4 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca605
b:0.1
occ:1.00
|
N
|
C:SER435
|
2.2
|
0.6
|
1.0
|
|
N
|
C:GLY434
|
2.3
|
0.5
|
1.0
|
|
O
|
C:THR432
|
2.3
|
0.7
|
1.0
|
|
OD2
|
C:ASP414
|
2.4
|
0.8
|
1.0
|
|
OE1
|
C:GLU415
|
2.4
|
0.4
|
1.0
|
|
CA
|
C:GLY434
|
2.5
|
0.3
|
1.0
|
|
C
|
C:GLY434
|
2.6
|
0.4
|
1.0
|
|
OD1
|
C:ASN431
|
2.6
|
0.3
|
1.0
|
|
O
|
C:SER435
|
2.7
|
0.0
|
1.0
|
|
C
|
C:LEU433
|
3.2
|
0.5
|
1.0
|
|
CA
|
C:SER435
|
3.2
|
0.3
|
1.0
|
|
C
|
C:SER435
|
3.3
|
0.4
|
1.0
|
|
C
|
C:THR432
|
3.5
|
0.3
|
1.0
|
|
O
|
C:GLY434
|
3.6
|
0.8
|
1.0
|
|
CD
|
C:GLU415
|
3.6
|
0.9
|
1.0
|
|
CG
|
C:ASP414
|
3.6
|
0.9
|
1.0
|
|
CG
|
C:ASN431
|
3.8
|
0.3
|
1.0
|
|
CA
|
C:LEU433
|
3.8
|
0.0
|
1.0
|
|
O
|
C:LEU433
|
4.0
|
0.6
|
1.0
|
|
N
|
C:LEU433
|
4.1
|
0.4
|
1.0
|
|
CB
|
C:GLU415
|
4.3
|
0.8
|
1.0
|
|
ND2
|
C:ASN431
|
4.4
|
0.3
|
1.0
|
|
N
|
C:THR432
|
4.4
|
0.7
|
1.0
|
|
OD1
|
C:ASP414
|
4.4
|
0.6
|
1.0
|
|
OE2
|
C:GLU415
|
4.5
|
0.6
|
1.0
|
|
CG
|
C:GLU415
|
4.5
|
0.4
|
1.0
|
|
CA
|
C:THR432
|
4.6
|
0.4
|
1.0
|
|
CB
|
C:SER435
|
4.6
|
0.8
|
1.0
|
|
CB
|
C:ASP414
|
4.6
|
0.1
|
1.0
|
|
N
|
C:PHE436
|
4.6
|
0.2
|
1.0
|
|
N
|
C:GLU415
|
4.8
|
1.0
|
1.0
|
|
Calcium binding site 5 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 5 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca606
b:1.0
occ:1.00
|
OD1
|
C:ASP452
|
2.4
|
0.9
|
1.0
|
|
OD2
|
C:ASP469
|
2.4
|
0.6
|
1.0
|
|
OD1
|
C:ASP469
|
2.4
|
0.1
|
1.0
|
|
O
|
C:GLN470
|
2.5
|
0.6
|
1.0
|
|
OD2
|
C:ASP452
|
2.5
|
0.4
|
1.0
|
|
OE1
|
C:GLU455
|
2.5
|
0.9
|
1.0
|
|
O
|
C:VAL453
|
2.6
|
0.5
|
1.0
|
|
CG
|
C:ASP469
|
2.7
|
0.5
|
1.0
|
|
CG
|
C:ASP452
|
2.7
|
0.7
|
1.0
|
|
CD
|
C:GLU455
|
3.4
|
0.3
|
1.0
|
|
C
|
C:GLN470
|
3.5
|
0.5
|
1.0
|
|
OE2
|
C:GLU455
|
3.7
|
0.9
|
1.0
|
|
C
|
C:VAL453
|
3.7
|
0.5
|
1.0
|
|
CB
|
C:ASP469
|
4.1
|
0.8
|
1.0
|
|
C
|
C:ASP469
|
4.1
|
95.3
|
1.0
|
|
N
|
C:GLN470
|
4.1
|
89.2
|
1.0
|
|
CB
|
C:ASP452
|
4.1
|
0.3
|
1.0
|
|
N
|
C:ILE471
|
4.3
|
0.4
|
1.0
|
|
O
|
C:ASP469
|
4.3
|
94.3
|
1.0
|
|
CA
|
C:GLN470
|
4.3
|
92.3
|
1.0
|
|
CA
|
C:ILE471
|
4.3
|
92.8
|
1.0
|
|
OG1
|
D:THR110
|
4.4
|
89.5
|
1.0
|
|
CA
|
C:ASN454
|
4.5
|
0.9
|
1.0
|
|
N
|
C:VAL453
|
4.5
|
0.7
|
1.0
|
|
N
|
C:GLU455
|
4.5
|
92.5
|
1.0
|
|
N
|
C:ASN454
|
4.5
|
0.5
|
1.0
|
|
C
|
C:ASP452
|
4.5
|
0.6
|
1.0
|
|
CA
|
C:ASP469
|
4.6
|
0.5
|
1.0
|
|
CA
|
C:VAL453
|
4.7
|
0.2
|
1.0
|
|
N
|
C:GLY472
|
4.8
|
79.3
|
1.0
|
|
CG
|
C:GLU455
|
4.8
|
1.0
|
1.0
|
|
CA
|
C:ASP452
|
4.8
|
0.6
|
1.0
|
|
O
|
C:ASP452
|
4.9
|
0.7
|
1.0
|
|
C
|
C:ASN454
|
5.0
|
0.1
|
1.0
|
|
Calcium binding site 6 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 6 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca607
b:0.4
occ:1.00
|
OE1
|
C:GLU493
|
2.4
|
0.6
|
1.0
|
|
OD1
|
C:ASP507
|
2.4
|
0.8
|
1.0
|
|
OD2
|
C:ASP507
|
2.4
|
0.5
|
1.0
|
|
OE2
|
C:GLU493
|
2.4
|
0.0
|
1.0
|
|
O
|
C:THR491
|
2.4
|
0.1
|
1.0
|
|
OD1
|
C:ASN490
|
2.5
|
0.6
|
1.0
|
|
O
|
C:LYS508
|
2.7
|
0.3
|
1.0
|
|
CD
|
C:GLU493
|
2.7
|
0.6
|
1.0
|
|
CG
|
C:ASP507
|
2.7
|
0.6
|
1.0
|
|
C
|
C:THR491
|
3.5
|
0.2
|
1.0
|
|
C
|
C:LYS508
|
3.6
|
0.3
|
1.0
|
|
CG
|
C:ASN490
|
3.6
|
0.4
|
1.0
|
|
CG
|
C:GLU493
|
4.2
|
0.6
|
1.0
|
|
CA
|
C:ILE509
|
4.2
|
0.2
|
1.0
|
|
N
|
C:LYS508
|
4.2
|
0.4
|
1.0
|
|
N
|
C:ILE509
|
4.2
|
0.7
|
1.0
|
|
ND2
|
C:ASN490
|
4.2
|
0.1
|
1.0
|
|
CB
|
C:ASP507
|
4.3
|
0.4
|
1.0
|
|
N
|
C:THR491
|
4.3
|
0.3
|
1.0
|
|
N
|
C:GLU493
|
4.3
|
0.2
|
1.0
|
|
N
|
C:ASP492
|
4.3
|
0.9
|
1.0
|
|
CA
|
C:ASP492
|
4.4
|
0.0
|
1.0
|
|
CA
|
C:THR491
|
4.4
|
0.4
|
1.0
|
|
C
|
C:ASN490
|
4.4
|
0.9
|
1.0
|
|
CA
|
C:LYS508
|
4.5
|
0.2
|
1.0
|
|
O
|
C:ASN490
|
4.6
|
0.9
|
1.0
|
|
N
|
C:ASN510
|
4.7
|
0.9
|
1.0
|
|
C
|
C:ASP507
|
4.7
|
0.3
|
1.0
|
|
O
|
C:GLY481
|
4.8
|
0.9
|
1.0
|
|
CB
|
C:ASN490
|
4.8
|
0.9
|
1.0
|
|
C
|
C:ASP492
|
4.9
|
0.7
|
1.0
|
|
CB
|
C:GLU493
|
4.9
|
0.1
|
1.0
|
|
CA
|
C:ASP507
|
5.0
|
0.7
|
1.0
|
|
CB
|
C:THR491
|
5.0
|
0.2
|
1.0
|
|
Calcium binding site 7 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 7 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca901
b:0.8
occ:1.00
|
OD1
|
E:ASP452
|
2.4
|
0.8
|
1.0
|
|
OD1
|
E:ASP469
|
2.4
|
0.2
|
1.0
|
|
OD2
|
E:ASP469
|
2.4
|
0.1
|
1.0
|
|
O
|
E:GLN470
|
2.4
|
0.2
|
1.0
|
|
OE1
|
E:GLU455
|
2.4
|
0.6
|
1.0
|
|
OD2
|
E:ASP452
|
2.5
|
0.8
|
1.0
|
|
O
|
E:VAL453
|
2.6
|
0.3
|
1.0
|
|
CG
|
E:ASP469
|
2.7
|
0.0
|
1.0
|
|
CG
|
E:ASP452
|
2.7
|
0.3
|
1.0
|
|
CD
|
E:GLU455
|
3.4
|
1.0
|
1.0
|
|
C
|
E:GLN470
|
3.4
|
0.7
|
1.0
|
|
OE2
|
E:GLU455
|
3.6
|
0.6
|
1.0
|
|
C
|
E:VAL453
|
3.8
|
0.5
|
1.0
|
|
C
|
E:ASP469
|
4.1
|
0.5
|
1.0
|
|
N
|
E:GLN470
|
4.1
|
0.8
|
1.0
|
|
CB
|
E:ASP469
|
4.1
|
0.0
|
1.0
|
|
CB
|
E:ASP452
|
4.1
|
0.8
|
1.0
|
|
O
|
E:ASP469
|
4.2
|
1.0
|
1.0
|
|
CA
|
E:GLN470
|
4.3
|
0.0
|
1.0
|
|
N
|
E:ILE471
|
4.3
|
0.2
|
1.0
|
|
CA
|
E:ILE471
|
4.4
|
0.3
|
1.0
|
|
OG1
|
F:THR110
|
4.4
|
0.8
|
1.0
|
|
N
|
E:VAL453
|
4.5
|
0.4
|
1.0
|
|
N
|
E:GLU455
|
4.5
|
0.2
|
1.0
|
|
CA
|
E:ASN454
|
4.5
|
0.6
|
1.0
|
|
CA
|
E:ASP469
|
4.6
|
1.0
|
1.0
|
|
C
|
E:ASP452
|
4.6
|
0.8
|
1.0
|
|
N
|
E:ASN454
|
4.6
|
0.1
|
1.0
|
|
CA
|
E:VAL453
|
4.7
|
0.1
|
1.0
|
|
CG
|
E:GLU455
|
4.8
|
0.8
|
1.0
|
|
N
|
E:GLY472
|
4.8
|
0.7
|
1.0
|
|
CA
|
E:ASP452
|
4.8
|
0.1
|
1.0
|
|
O
|
E:ASP452
|
4.9
|
0.8
|
1.0
|
|
Calcium binding site 8 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 8 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca902
b:0.1
occ:1.00
|
O
|
E:LYS508
|
1.8
|
0.1
|
1.0
|
|
OE1
|
E:GLU493
|
2.4
|
0.3
|
1.0
|
|
OE2
|
E:GLU493
|
2.4
|
0.5
|
1.0
|
|
OD2
|
E:ASP507
|
2.5
|
0.7
|
1.0
|
|
OD1
|
E:ASP507
|
2.5
|
0.7
|
1.0
|
|
C
|
E:LYS508
|
2.5
|
0.4
|
1.0
|
|
OD1
|
E:ASN490
|
2.7
|
0.3
|
1.0
|
|
O
|
E:THR491
|
2.7
|
0.8
|
1.0
|
|
CD
|
E:GLU493
|
2.7
|
0.9
|
1.0
|
|
CG
|
E:ASP507
|
2.8
|
0.2
|
1.0
|
|
N
|
E:ILE509
|
3.2
|
0.7
|
1.0
|
|
CA
|
E:ILE509
|
3.3
|
0.7
|
1.0
|
|
N
|
E:LYS508
|
3.6
|
0.2
|
1.0
|
|
CA
|
E:LYS508
|
3.6
|
0.1
|
1.0
|
|
CG
|
E:ASN490
|
3.8
|
0.9
|
1.0
|
|
C
|
E:THR491
|
3.8
|
0.2
|
1.0
|
|
N
|
E:ASN510
|
4.1
|
0.2
|
1.0
|
|
C
|
E:ILE509
|
4.2
|
0.4
|
1.0
|
|
CG
|
E:GLU493
|
4.2
|
0.8
|
1.0
|
|
CB
|
E:ASP507
|
4.3
|
0.5
|
1.0
|
|
ND2
|
E:ASN490
|
4.3
|
0.6
|
1.0
|
|
C
|
E:ASP507
|
4.3
|
0.7
|
1.0
|
|
CG1
|
E:ILE509
|
4.3
|
0.8
|
1.0
|
|
CB
|
E:ILE509
|
4.4
|
0.6
|
1.0
|
|
N
|
E:GLU493
|
4.5
|
0.9
|
1.0
|
|
O
|
E:GLU511
|
4.6
|
0.7
|
1.0
|
|
N
|
E:THR491
|
4.7
|
0.7
|
1.0
|
|
N
|
E:ASP492
|
4.7
|
0.9
|
1.0
|
|
CA
|
E:ASP492
|
4.7
|
0.3
|
1.0
|
|
CA
|
E:ASP507
|
4.8
|
0.2
|
1.0
|
|
CA
|
E:THR491
|
4.8
|
0.1
|
1.0
|
|
C
|
E:ASN490
|
4.8
|
0.0
|
1.0
|
|
CB
|
E:LYS508
|
4.9
|
0.9
|
1.0
|
|
O
|
E:GLY481
|
5.0
|
0.9
|
1.0
|
|
Calcium binding site 9 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 9 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca901
b:0.6
occ:1.00
|
OD1
|
G:ASP469
|
2.4
|
0.5
|
1.0
|
|
OD1
|
G:ASP452
|
2.4
|
0.1
|
1.0
|
|
OD2
|
G:ASP469
|
2.4
|
0.7
|
1.0
|
|
OD2
|
G:ASP452
|
2.4
|
0.3
|
1.0
|
|
O
|
G:GLN470
|
2.5
|
0.7
|
1.0
|
|
OE1
|
G:GLU455
|
2.5
|
0.3
|
1.0
|
|
O
|
G:VAL453
|
2.6
|
0.8
|
1.0
|
|
CG
|
G:ASP469
|
2.7
|
0.8
|
1.0
|
|
CG
|
G:ASP452
|
2.7
|
0.5
|
1.0
|
|
CD
|
G:GLU455
|
3.4
|
95.3
|
1.0
|
|
C
|
G:GLN470
|
3.5
|
0.2
|
1.0
|
|
OE2
|
G:GLU455
|
3.7
|
90.5
|
1.0
|
|
C
|
G:VAL453
|
3.7
|
1.0
|
1.0
|
|
N
|
G:GLN470
|
4.1
|
0.6
|
1.0
|
|
C
|
G:ASP469
|
4.1
|
0.5
|
1.0
|
|
CB
|
G:ASP469
|
4.1
|
0.3
|
1.0
|
|
CB
|
G:ASP452
|
4.1
|
0.1
|
1.0
|
|
CA
|
G:GLN470
|
4.3
|
0.4
|
1.0
|
|
O
|
G:ASP469
|
4.3
|
0.5
|
1.0
|
|
N
|
G:ILE471
|
4.3
|
0.9
|
1.0
|
|
CA
|
G:ASN454
|
4.4
|
0.1
|
1.0
|
|
N
|
G:GLU455
|
4.4
|
0.4
|
1.0
|
|
CA
|
G:ILE471
|
4.4
|
0.2
|
1.0
|
|
N
|
G:ASN454
|
4.5
|
0.5
|
1.0
|
|
OG1
|
H:THR110
|
4.5
|
0.8
|
1.0
|
|
N
|
G:VAL453
|
4.5
|
0.3
|
1.0
|
|
C
|
G:ASP452
|
4.6
|
0.4
|
1.0
|
|
CA
|
G:ASP469
|
4.6
|
0.8
|
1.0
|
|
CA
|
G:VAL453
|
4.7
|
0.2
|
1.0
|
|
CG
|
G:GLU455
|
4.8
|
95.3
|
1.0
|
|
CA
|
G:ASP452
|
4.9
|
0.8
|
1.0
|
|
N
|
G:GLY472
|
4.9
|
0.2
|
1.0
|
|
O
|
G:ASP452
|
4.9
|
0.6
|
1.0
|
|
C
|
G:ASN454
|
4.9
|
0.8
|
1.0
|
|
Calcium binding site 10 out
of 10 in 4xlw
Go back to
Calcium Binding Sites List in 4xlw
Calcium binding site 10 out
of 10 in the Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2)
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 10 of Complex of NOTCH1 (EGF11-13) Bound to Delta-Like 4 (N-EGF2) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca902
b:1.0
occ:1.00
|
OE1
|
G:GLU493
|
2.4
|
0.1
|
1.0
|
|
OD1
|
G:ASP507
|
2.4
|
0.9
|
1.0
|
|
OE2
|
G:GLU493
|
2.4
|
0.3
|
1.0
|
|
OD2
|
G:ASP507
|
2.4
|
0.4
|
1.0
|
|
O
|
G:THR491
|
2.4
|
0.0
|
1.0
|
|
OD1
|
G:ASN490
|
2.5
|
0.2
|
1.0
|
|
O
|
G:LYS508
|
2.6
|
0.8
|
1.0
|
|
CD
|
G:GLU493
|
2.7
|
0.1
|
1.0
|
|
CG
|
G:ASP507
|
2.7
|
0.6
|
1.0
|
|
C
|
G:THR491
|
3.5
|
0.4
|
1.0
|
|
C
|
G:LYS508
|
3.5
|
0.7
|
1.0
|
|
CG
|
G:ASN490
|
3.6
|
0.9
|
1.0
|
|
N
|
G:LYS508
|
4.1
|
0.3
|
1.0
|
|
CG
|
G:GLU493
|
4.2
|
0.1
|
1.0
|
|
N
|
G:ILE509
|
4.2
|
0.3
|
1.0
|
|
N
|
G:GLU493
|
4.2
|
1.0
|
1.0
|
|
CA
|
G:ILE509
|
4.2
|
0.1
|
1.0
|
|
ND2
|
G:ASN490
|
4.2
|
0.0
|
1.0
|
|
N
|
G:ASP492
|
4.2
|
0.1
|
1.0
|
|
CB
|
G:ASP507
|
4.2
|
0.5
|
1.0
|
|
CA
|
G:ASP492
|
4.3
|
0.8
|
1.0
|
|
N
|
G:THR491
|
4.3
|
0.7
|
1.0
|
|
CA
|
G:LYS508
|
4.4
|
0.9
|
1.0
|
|
C
|
G:ASN490
|
4.4
|
0.3
|
1.0
|
|
CA
|
G:THR491
|
4.5
|
0.3
|
1.0
|
|
O
|
G:ASN490
|
4.5
|
0.6
|
1.0
|
|
C
|
G:ASP507
|
4.7
|
0.6
|
1.0
|
|
CB
|
G:ASN490
|
4.7
|
0.2
|
1.0
|
|
N
|
G:ASN510
|
4.8
|
1.0
|
1.0
|
|
C
|
G:ASP492
|
4.8
|
0.6
|
1.0
|
|
O
|
G:GLY481
|
4.8
|
0.4
|
1.0
|
|
CB
|
G:GLU493
|
4.9
|
0.7
|
1.0
|
|
CA
|
G:ASP507
|
4.9
|
0.6
|
1.0
|
|
Reference:
V.C.Luca,
K.M.Jude,
N.W.Pierce,
M.V.Nachury,
S.Fischer,
K.C.Garcia.
Structural Basis For NOTCH1 Engagement of Delta-Like 4. Science V. 347 2015.
ISSN: ESSN 1095-9203
DOI: 10.1126/SCIENCE.1261093
Page generated: Sun Jul 14 14:37:11 2024
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