Calcium in PDB 4y99: Core Domain of Human Cardiac Troponin

The structure of Core Domain of Human Cardiac Troponin, PDB code: 4y99 was solved by S.Takeda, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	66.062, 80.368, 93.712, 90.00, 90.00, 90.00
R / Rfree (%)	23 / 25.9

The binding sites of Calcium atom in the Core Domain of Human Cardiac Troponin (pdb code 4y99). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Core Domain of Human Cardiac Troponin, PDB code: 4y99:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Core Domain of Human Cardiac Troponin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Core Domain of Human Cardiac Troponin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca201 b:27.5 occ:1.00 OD2 A:ASP65 2.1 40.3 1.0 O A:HOH319 2.1 27.1 1.0 O A:THR71 2.4 36.6 1.0 OG A:SER69 2.4 39.5 1.0 OD2 A:ASP67 2.4 42.5 1.0 OE2 A:GLU76 2.5 36.6 1.0 OE1 A:GLU76 2.6 38.4 1.0 CD A:GLU76 2.9 37.4 1.0 CG A:ASP65 3.3 41.5 1.0 CG A:ASP67 3.3 43.8 1.0 C A:THR71 3.5 37.5 1.0 CB A:SER69 3.5 42.4 1.0 OD1 A:ASP67 3.6 43.4 1.0 OD1 A:ASP65 4.0 43.3 1.0 N A:SER69 4.1 42.1 1.0 N A:THR71 4.2 39.1 1.0 OG1 A:THR71 4.2 38.4 1.0 CA A:ASP65 4.3 41.8 1.0 CA A:SER69 4.3 42.0 1.0 CB A:ASP65 4.3 41.4 1.0 N A:GLU66 4.4 43.3 1.0 CA A:THR71 4.4 38.4 1.0 N A:VAL72 4.4 36.3 1.0 N A:ASP67 4.4 43.4 1.0 CG A:GLU76 4.4 33.0 1.0 OD2 A:ASP73 4.5 43.4 1.0 CA A:VAL72 4.5 34.5 1.0 N A:ASP73 4.5 34.2 1.0 CB A:ASP67 4.7 43.1 1.0 C A:ASP65 4.8 42.6 1.0 N A:GLY70 4.8 41.1 1.0 C A:SER69 4.8 41.5 1.0 CG A:ASP73 4.9 38.2 1.0 C A:VAL72 5.0 34.7 1.0 CA A:ASP67 5.0 43.5 1.0 CB A:THR71 5.0 39.0 1.0 N A:GLY68 5.0 42.6 1.0

Calcium binding site 2 out of 3 in the Core Domain of Human Cardiac Troponin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Core Domain of Human Cardiac Troponin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca202 b:29.6 occ:1.00 O A:ARG147 2.3 42.5 1.0 OD1 A:ASP141 2.4 45.1 1.0 OE1 A:GLU152 2.4 41.4 1.0 O A:HOH321 2.4 32.5 1.0 OD1 A:ASN143 2.4 50.5 1.0 OD1 A:ASP145 2.4 46.7 1.0 OE2 A:GLU152 2.6 42.0 1.0 CD A:GLU152 2.9 40.4 1.0 CG A:ASP145 3.3 49.0 1.0 CG A:ASP141 3.4 47.7 1.0 C A:ARG147 3.5 43.3 1.0 CG A:ASN143 3.6 50.8 1.0 OD2 A:ASP145 3.6 50.5 1.0 CA A:ASP141 4.0 47.4 1.0 CB A:ASP141 4.1 47.8 1.0 ND2 A:ASN143 4.2 52.4 1.0 N A:ASN143 4.2 49.1 1.0 N A:ARG147 4.2 45.9 1.0 OD2 A:ASP141 4.3 48.0 1.0 N A:ILE148 4.3 41.7 1.0 CG A:GLU152 4.3 37.7 1.0 N A:ASP145 4.4 49.0 1.0 CA A:ILE148 4.4 40.1 1.0 CA A:ARG147 4.4 45.1 1.0 N A:LYS142 4.4 48.5 1.0 C A:ASP141 4.4 48.3 1.0 N A:ASP149 4.4 39.5 1.0 CB A:ASP145 4.6 49.5 1.0 CG A:ARG147 4.6 48.1 1.0 CB A:ASN143 4.7 49.5 1.0 O A:HOH322 4.7 39.4 1.0 CA A:ASN143 4.8 49.6 1.0 N A:ASN144 4.8 49.6 1.0 OD1 A:ASP149 4.8 45.2 1.0 C A:ASN143 4.8 50.2 1.0 CA A:ASP145 4.9 49.1 1.0 C A:ILE148 4.9 39.9 1.0 N A:GLY146 4.9 47.9 1.0

Calcium binding site 3 out of 3 in the Core Domain of Human Cardiac Troponin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Core Domain of Human Cardiac Troponin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca203 b:29.6 occ:1.00 O A:HOH320 2.1 35.3 1.0 O A:TYR111 2.3 42.4 1.0 OD1 A:ASN107 2.4 48.1 1.0 OD2 A:ASP109 2.4 44.5 1.0 OD1 A:ASP105 2.4 42.3 1.0 OE2 A:GLU116 2.5 44.2 1.0 OE1 A:GLU116 2.5 45.1 1.0 CD A:GLU116 2.9 45.2 1.0 CG A:ASP109 3.2 47.9 1.0 CG A:ASN107 3.4 50.4 1.0 C A:TYR111 3.5 41.9 1.0 CG A:ASP105 3.5 43.0 1.0 OD1 A:ASP109 3.7 48.5 1.0 ND2 A:ASN107 4.0 50.1 1.0 CA A:ASP105 4.1 43.3 1.0 N A:TYR111 4.2 42.4 1.0 N A:ASP109 4.2 47.1 1.0 CA A:TYR111 4.3 41.8 1.0 CB A:ASP105 4.3 42.8 1.0 N A:ASN107 4.4 49.2 1.0 OD2 A:ASP105 4.4 42.3 1.0 CG A:GLU116 4.4 46.0 1.0 C A:ASP105 4.4 44.5 1.0 CB A:ASP109 4.4 47.6 1.0 N A:ILE112 4.4 41.7 1.0 OD1 A:ASP113 4.4 53.3 1.0 CA A:ILE112 4.5 42.2 1.0 N A:ASP113 4.5 44.7 1.0 N A:LYS106 4.5 46.7 1.0 CB A:ASN107 4.6 50.2 1.0 N A:ALA108 4.7 48.2 1.0 CA A:ASP109 4.7 46.8 1.0 CB A:TYR111 4.8 42.2 1.0 CA A:ASN107 4.8 49.7 1.0 CG A:ASP113 4.8 49.4 1.0 N A:GLY110 4.9 44.5 1.0 C A:ASN107 4.9 49.1 1.0 O A:ASP105 4.9 44.3 1.0 C A:ILE112 4.9 43.5 1.0

S.Takeda, S.Fujiwara. Core Domain of Human Cardiac Troponin To Be Published.