Calcium in PDB 4ydo: Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form

All present enzymatic activity of Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form:
2.5.1.58; 2.5.1.59;

The structure of Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form, PDB code: 4ydo was solved by S.Kumar, M.F.Mabanglo, M.A.Hast, Y.Shi, L.S.Beese, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.30 / 3.00
Space group	P 43 2 2
Cell size a, b, c (Å), α, β, γ (°)	96.824, 96.824, 189.082, 90.00, 90.00, 90.00
R / Rfree (%)	22.6 / 24.9

The structure of Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Calcium atom in the Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form (pdb code 4ydo). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form, PDB code: 4ydo:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca401 b:57.1 occ:0.51 OD1 A:ASP158 2.4 57.4 1.0 O A:HOH509 2.4 57.0 1.0 O A:HOH506 2.4 54.5 1.0 O A:HOH515 3.3 52.0 1.0 CG A:ASP158 3.3 56.7 1.0 OD2 A:ASP158 3.6 56.5 1.0 O A:ASP155 3.9 52.4 1.0 NZ A:LYS193 4.0 59.4 1.0 CE A:LYS193 4.6 59.3 1.0 CB A:ASP158 4.7 56.6 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca602 b:69.5 occ:1.00 O B:HOH724 2.4 59.8 1.0 O B:HOH715 2.4 67.9 1.0 SG B:CYS402 2.7 78.5 1.0 CA B:CYS402 3.5 77.0 1.0 CB B:CYS402 3.5 77.7 1.0 C B:CYS402 4.2 75.6 1.0 N B:TRP403 4.3 79.7 1.0 CB B:GLU404 4.4 81.0 1.0 CG B:GLU404 4.6 82.2 1.0 N B:GLU404 4.6 79.6 1.0 N B:CYS402 4.6 76.6 1.0 O B:VAL401 4.8 80.6 1.0

S.Kumar, M.F.Mabanglo, M.A.Hast, Y.Shi, L.S.Beese. Crystal Structure of Candida Albicans Protein Farnesyltransferase in Apo Form To Be Published.