Calcium in PDB 4z8n: Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A)

The structure of Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A), PDB code: 4z8n was solved by J.Gruszczyk, W.H.Tham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.84 / 2.12
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	58.790, 93.450, 126.720, 90.00, 90.00, 90.00
R / Rfree (%)	20.3 / 22.9

The structure of Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A) also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Chlorine	(Cl)	1 atom

The binding sites of Calcium atom in the Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A) (pdb code 4z8n). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A), PDB code: 4z8n:

Calcium binding site 1 out of 1 in the Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A) within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca503 b:95.5 occ:1.00 O B:HOH663 2.5 70.3 1.0 OE1 B:GLU277 2.5 76.0 1.0 N B:ASN275 3.4 47.0 1.0 O B:HOH672 3.6 53.1 1.0 CD B:GLU277 3.7 72.3 1.0 CA B:ASN275 3.9 46.6 1.0 N B:MET276 4.2 41.8 1.0 O B:GLN273 4.3 46.4 1.0 C B:ALA274 4.3 46.5 1.0 OE2 B:GLU277 4.3 78.1 1.0 CA B:ALA274 4.4 47.0 1.0 C B:ASN275 4.5 44.4 1.0 O B:HOH664 4.7 50.7 1.0 N B:GLU277 4.9 37.8 1.0 CG B:GLU277 4.9 61.0 1.0 CG B:MET276 5.0 49.0 1.0

J.Gruszczyk, N.T.Lim, A.Arnott, W.Q.He, W.Nguitragool, W.Roobsoong, Y.F.Mok, J.M.Murphy, K.R.Smith, S.Lee, M.Bahlo, I.Mueller, A.E.Barry, W.H.Tham. Structurally Conserved Erythrocyte-Binding Domain in Plasmodium Provides A Versatile Scaffold For Alternate Receptor Engagement. Proc.Natl.Acad.Sci.Usa V. 113 E191 2016.
ISSN: ESSN 1091-6490
PubMed: 26715754
DOI: 10.1073/PNAS.1516512113