Calcium in PDB 5acr: W228Y-Investigation of the Impact From Residues W228 and Y233 in the Metallo-Beta-Lactamase Gim-1

The structure of W228Y-Investigation of the Impact From Residues W228 and Y233 in the Metallo-Beta-Lactamase Gim-1, PDB code: 5acr was solved by S.Skagseth, T.J.Carlsen, G.E.K.Bjerga, J.Spencer, O.Samuelsen, H.-K.S.Leiros, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.747 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	38.532, 129.732, 40.396, 90.00, 96.50, 90.00
R / Rfree (%)	20.17 / 24.42

The structure of W228Y-Investigation of the Impact From Residues W228 and Y233 in the Metallo-Beta-Lactamase Gim-1 also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Calcium atom in the W228Y-Investigation of the Impact From Residues W228 and Y233 in the Metallo-Beta-Lactamase Gim-1 (pdb code 5acr). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the W228Y-Investigation of the Impact From Residues W228 and Y233 in the Metallo-Beta-Lactamase Gim-1, PDB code: 5acr:

Calcium binding site 1 out of 1 in the W228Y-Investigation of the Impact From Residues W228 and Y233 in the Metallo-Beta-Lactamase Gim-1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of W228Y-Investigation of the Impact From Residues W228 and Y233 in the Metallo-Beta-Lactamase Gim-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1297 b:46.1 occ:1.00 OG A:SER112 2.8 21.5 1.0 O A:TYR137 2.9 21.6 1.0 OG A:SER114 3.2 19.6 1.0 N A:SER114 3.3 17.6 1.0 N A:TYR137 3.5 23.0 1.0 C A:ILE113 3.6 15.7 1.0 C A:SER112 3.7 18.1 1.0 CB A:SER112 3.7 21.9 1.0 CA A:ILE113 3.7 17.1 1.0 CB A:SER114 3.7 17.0 1.0 O A:SER112 3.7 20.2 1.0 CG1 A:ILE125 3.7 19.3 1.0 N A:ILE113 3.8 19.1 1.0 C A:TYR137 3.9 17.8 1.0 CD1 A:ILE125 3.9 19.0 1.0 CB A:THR136 3.9 23.8 1.0 CA A:SER114 4.1 16.8 1.0 CA A:THR136 4.2 20.4 1.0 C A:THR136 4.2 20.0 1.0 O A:ILE113 4.3 16.0 1.0 CA A:TYR137 4.3 22.4 1.0 CA A:SER112 4.3 17.6 1.0 CG2 A:THR138 4.5 15.3 1.0 CG2 A:THR136 4.5 22.8 1.0 CG2 A:THR85 4.8 23.3 1.0 N A:THR138 4.9 20.8 1.0

S.Skagseth, T.J.Carlsen, G.E.K.Bjerga, J.Spencer, O.Samuelsen, H.S.Leiros. Role of Residues W228 and Y233 in the Structure and Activity of Metallo-Beta-Lactamase Gim-1. Antimicrob.Agents Chemother. V. 60 990 2015.
ISSN: ISSN 0066-4804
PubMed: 26643332
DOI: 10.1128/AAC.02017-15