Calcium in PDB 5c02: Influenza A M2 Transmembrane Domain Drug-Resistant S31N Mutant at pH 8.0

The structure of Influenza A M2 Transmembrane Domain Drug-Resistant S31N Mutant at pH 8.0, PDB code: 5c02 was solved by J.L.Thomaston, W.F.Degrado, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	17.84 / 1.59
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	28.650, 28.650, 68.380, 90.00, 90.00, 90.00
R / Rfree (%)	16 / 19.7

The structure of Influenza A M2 Transmembrane Domain Drug-Resistant S31N Mutant at pH 8.0 also contains other interesting chemical elements:

Strontium	(Sr)	1 atom
Chlorine	(Cl)	2 atoms

The binding sites of Calcium atom in the Influenza A M2 Transmembrane Domain Drug-Resistant S31N Mutant at pH 8.0 (pdb code 5c02). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Influenza A M2 Transmembrane Domain Drug-Resistant S31N Mutant at pH 8.0, PDB code: 5c02:

Calcium binding site 1 out of 1 in the Influenza A M2 Transmembrane Domain Drug-Resistant S31N Mutant at pH 8.0


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Influenza A M2 Transmembrane Domain Drug-Resistant S31N Mutant at pH 8.0 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca103 b:13.6 occ:0.52 O25 A:OLC105 2.3 23.7 0.6 O A:HOH202 2.4 29.4 1.0 HO25 A:OLC105 2.5 28.4 0.6 O A:HOH208 2.5 43.1 1.0 O20 A:OLC105 2.5 24.3 0.6 H24 A:OLC105 3.0 45.8 0.6 C24 A:OLC105 3.1 38.2 0.6 C21 A:OLC105 3.4 42.7 0.6 C1 A:OLC105 3.5 34.7 0.6 H21 A:OLC105 3.5 51.2 0.6 H22 A:OLC105 3.5 46.8 0.6 C22 A:OLC105 3.5 39.0 0.6 O19 A:OLC105 3.8 44.5 0.6 H24A A:OLC105 3.9 45.8 0.6 H21A A:OLC105 4.3 51.2 0.6 C2 A:OLC105 4.6 45.0 0.6 H2A A:OLC105 4.6 53.9 0.6 H2 A:OLC105 4.7 53.9 0.6 O23 A:OLC105 4.9 32.0 0.6

J.L.Thomaston, W.F.Degrado. Crystal Structure of the Drug-Resistant S31N Influenza M2 Proton Channel. Protein Sci. V. 25 1551 2016.
ISSN: ESSN 1469-896X
PubMed: 27082171
DOI: 10.1002/PRO.2937