Calcium in PDB 5c5c: Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain

The structure of Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain, PDB code: 5c5c was solved by A.Dong, E.Dobrovetsky, A.Hutchinson, W.Tempel, A.M.Edwards, C.Bountra, C.H.Arrowsmith, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.86
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	106.175, 101.203, 55.318, 90.00, 110.46, 90.00
R / Rfree (%)	20.6 / 24.8

The binding sites of Calcium atom in the Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain (pdb code 5c5c). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain, PDB code: 5c5c:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca603 b:40.6 occ:1.00 O A:LEU95 2.4 38.2 1.0 O A:ASP92 2.6 43.5 1.0 O A:HOH737 2.6 43.7 1.0 O A:ILE89 2.6 36.5 1.0 O A:LEU96 2.9 39.4 1.0 C A:LEU96 3.5 40.9 1.0 C A:LEU95 3.6 40.4 1.0 C A:ASP92 3.7 45.8 1.0 C A:ILE89 3.8 37.7 1.0 N A:ASP92 4.1 43.6 1.0 CB A:LEU96 4.2 39.5 1.0 N A:PRO97 4.2 43.2 1.0 CA A:LEU96 4.2 39.6 1.0 CA A:ASN90 4.2 37.0 1.0 CA A:PRO97 4.3 44.0 1.0 CA A:ASP92 4.3 43.4 1.0 C A:ASN90 4.3 41.1 1.0 N A:LEU96 4.3 37.4 1.0 N A:ASN90 4.5 36.6 1.0 CB A:ASP92 4.5 42.5 1.0 O A:ASN90 4.5 43.8 1.0 CG2 A:ILE89 4.6 38.3 1.0 O A:PRO97 4.6 48.4 1.0 C A:PRO97 4.6 44.6 1.0 O A:VAL99 4.6 38.9 1.0 CA A:LEU95 4.7 42.1 1.0 N A:PRO93 4.8 48.0 1.0 N A:LEU95 4.8 44.8 1.0 N A:SER91 4.9 40.1 0.5 N A:SER91 4.9 40.7 0.5 CA A:ILE89 4.9 37.2 1.0 CA A:PRO93 5.0 48.5 1.0

Calcium binding site 2 out of 2 in the Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca604 b:37.0 occ:1.00 O A:ASN470 2.6 40.6 1.0 O A:LEU186 2.7 35.1 1.0 OD1 A:ASP189 2.8 44.2 1.0 O A:PHE195 2.8 30.8 1.0 O A:TYR192 2.8 38.7 1.0 O A:HOH739 3.1 32.3 1.0 NH2 A:ARG453 3.6 38.0 1.0 C A:ASN470 3.8 40.6 1.0 C A:PHE195 3.8 32.0 1.0 C A:TYR192 3.9 39.1 1.0 C A:LEU186 3.9 34.6 1.0 CG A:ASP189 4.0 49.2 1.0 C A:SER187 4.1 42.1 1.0 CA A:SER187 4.2 38.5 1.0 CB A:PHE195 4.2 31.6 1.0 O A:SER187 4.2 46.1 1.0 CB A:TYR192 4.2 38.7 1.0 CD1 A:PHE195 4.2 32.0 1.0 CA A:PHE195 4.4 31.9 1.0 N A:SER187 4.5 36.0 1.0 O A:ASP188 4.6 42.9 1.0 N A:PHE195 4.6 32.5 1.0 CA A:ASP189 4.6 46.9 1.0 C A:ASP188 4.6 42.2 1.0 CZ A:ARG453 4.7 39.1 1.0 CA A:TYR192 4.7 40.6 1.0 N A:ASP189 4.7 43.5 1.0 N A:ASP188 4.7 42.4 1.0 N A:GLY471 4.7 35.8 1.0 CG A:PHE195 4.7 31.4 1.0 CA A:ASN470 4.7 42.0 1.0 CA A:GLY471 4.7 36.1 1.0 OD2 A:ASP189 4.8 46.0 1.0 N A:ASP193 4.8 38.6 1.0 N A:SER196 4.9 29.2 1.0 CB A:ASP189 4.9 46.8 1.0 CA A:ASP193 5.0 40.8 1.0

E.Dobrovetsky, A.Dong, A.Hutchinson, W.Tempel, A.M.Edwards, C.Bountra, C.H.Arrowsmith, Structural Genomics Consortium (Sgc). Human Metabotropic Glutamate Receptor 7, Extracellular Ligand Binding Domain To Be Published.