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Atomistry » Calcium » PDB 5cxl-5da8 » 5d3c | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Calcium » PDB 5cxl-5da8 » 5d3c » |
Calcium in PDB 5d3c: Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470Enzymatic activity of Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470
All present enzymatic activity of Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470:
3.4.24.65; Protein crystallography data
The structure of Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470, PDB code: 5d3c
was solved by
C.Rouanet-Mehouas,
L.Devel,
V.Dive,
E.A.Stura,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5d3c:
The structure of Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470 also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470
(pdb code 5d3c). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470, PDB code: 5d3c: Jump to Calcium binding site number: 1; 2; 3; Calcium binding site 1 out of 3 in 5d3cGo back to Calcium Binding Sites List in 5d3c
Calcium binding site 1 out
of 3 in the Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470
Mono view Stereo pair view
Calcium binding site 2 out of 3 in 5d3cGo back to Calcium Binding Sites List in 5d3c
Calcium binding site 2 out
of 3 in the Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470
Mono view Stereo pair view
Calcium binding site 3 out of 3 in 5d3cGo back to Calcium Binding Sites List in 5d3c
Calcium binding site 3 out
of 3 in the Crystal Structure of A Double Mutant Catalytic Domain of Human MMP12 in Complex with An Hydroxamate Analogue of RXP470
Mono view Stereo pair view
Reference:
C.Rouanet-Mehouas,
B.Czarny,
F.Beau,
E.Cassar-Lajeunesse,
E.A.Stura,
V.Dive,
L.Devel.
Zinc-Metalloproteinase Inhibitors: Evaluation of the Complex Role Played By the Zinc-Binding Group on Potency and Selectivity. J. Med. Chem. V. 60 403 2017.
Page generated: Sun Jul 14 17:46:15 2024
ISSN: ISSN 1520-4804 PubMed: 27996256 DOI: 10.1021/ACS.JMEDCHEM.6B01420 |
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