Calcium in PDB 5dlf: Crystal Structure of Human Dna Polymerase Eta Inserting Datp Opposite O4-Methylhymidine

All present enzymatic activity of Crystal Structure of Human Dna Polymerase Eta Inserting Datp Opposite O4-Methylhymidine:
2.7.7.7;

The structure of Crystal Structure of Human Dna Polymerase Eta Inserting Datp Opposite O4-Methylhymidine, PDB code: 5dlf was solved by A.Patra, D.K.Oflaherty, M.Egli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.51 / 1.97
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	99.026, 99.026, 82.166, 90.00, 90.00, 120.00
R / Rfree (%)	16.4 / 21.7

The binding sites of Calcium atom in the Crystal Structure of Human Dna Polymerase Eta Inserting Datp Opposite O4-Methylhymidine (pdb code 5dlf). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of Human Dna Polymerase Eta Inserting Datp Opposite O4-Methylhymidine, PDB code: 5dlf:

Calcium binding site 1 out of 1 in the Crystal Structure of Human Dna Polymerase Eta Inserting Datp Opposite O4-Methylhymidine


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human Dna Polymerase Eta Inserting Datp Opposite O4-Methylhymidine within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca502 b:12.9 occ:1.00 OD1 A:ASP115 2.2 11.2 1.0 O1B A:DTP501 2.2 14.3 1.0 O1G A:DTP501 2.3 33.1 1.0 O1A A:DTP501 2.3 17.0 1.0 OD1 A:ASP13 2.3 12.2 1.0 O A:MET14 2.3 9.3 1.0 CG A:ASP115 3.3 13.8 1.0 CG A:ASP13 3.4 14.0 1.0 PB A:DTP501 3.5 17.5 1.0 C A:MET14 3.5 8.9 1.0 PA A:DTP501 3.6 17.2 1.0 PG A:DTP501 3.7 49.8 1.0 OD2 A:ASP115 3.7 14.3 1.0 O A:HOH635 3.8 32.0 1.0 O3A A:DTP501 3.8 17.9 1.0 C5' A:DTP501 3.9 17.0 1.0 OD2 A:ASP13 3.9 18.9 1.0 N A:MET14 4.0 9.1 1.0 O3B A:DTP501 4.0 21.5 1.0 O5' A:DTP501 4.2 15.9 1.0 O A:HOH688 4.3 10.2 1.0 CA A:MET14 4.3 9.6 1.0 O3G A:DTP501 4.3 22.7 1.0 C A:ASP13 4.4 9.4 1.0 N A:ASP15 4.5 8.3 1.0 CB A:ASP115 4.5 12.4 1.0 N A:CYS16 4.6 8.9 1.0 CB A:ASP13 4.6 11.7 1.0 CA A:ASP15 4.7 8.9 1.0 CB A:PHE17 4.7 8.3 1.0 CB A:MET14 4.7 10.6 1.0 N A:PHE17 4.7 8.5 1.0 C A:ASP15 4.8 8.9 1.0 O2B A:DTP501 4.8 13.7 1.0 O A:ASP13 4.8 8.4 1.0 CA A:ASP13 4.8 10.4 1.0 O A:ASP115 4.8 11.9 1.0 O2A A:DTP501 4.9 17.3 1.0 O2G A:DTP501 4.9 31.8 1.0 NZ A:LYS231 5.0 30.6 1.0

D.K.O'flaherty, A.Patra, Y.Su, F.P.Guengerich, M.Egli, C.J.Wilds. Lesion Orientation OFO4-Alkylthymidine Influences Replication By Human Dna Polymeraseeta. Chem Sci V. 7 4896 2016.
ISSN: ISSN 2041-6520
PubMed: 27574558
DOI: 10.1039/C6SC00666C