Calcium in PDB 5emw: Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor

The structure of Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor, PDB code: 5emw was solved by C.L.Noland, S.Gierke, P.D.Schnier, J.Murray, W.N.Sandoval, M.Sagolla, A.Dey, R.N.Hannoush, W.J.Fairbrother, C.N.Cunningham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	95.54 / 2.55
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	65.310, 123.530, 150.730, 90.00, 90.00, 90.00
R / Rfree (%)	18.4 / 22.3

The binding sites of Calcium atom in the Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor (pdb code 5emw). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor, PDB code: 5emw:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca501 b:42.8 occ:1.00 O C:HOH536 2.5 45.5 1.0 CB B:TYR353 3.3 25.9 1.0 CG B:TYR353 3.4 26.2 1.0 O B:HOH608 3.7 30.8 1.0 CD2 B:TYR353 3.8 26.3 1.0 N C:ASN358 3.8 28.8 1.0 O C:LEU356 3.8 29.6 1.0 CD1 B:TYR353 3.8 26.6 1.0 CA C:GLU357 4.0 28.6 1.0 CE2 A:TYR353 4.2 30.2 1.0 CD2 A:TYR353 4.3 23.8 1.0 C C:GLU357 4.4 30.1 1.0 C C:LEU356 4.5 27.9 1.0 CE2 B:TYR353 4.5 28.4 1.0 CE1 B:TYR353 4.6 27.1 1.0 N C:GLU357 4.6 28.4 1.0 CA B:TYR353 4.8 33.7 1.0 CA C:ASN358 4.8 30.4 1.0 CZ A:TYR353 4.8 36.8 1.0 O B:ALA354 4.9 30.2 1.0 CG C:GLU357 4.9 33.1 1.0 CZ B:TYR353 4.9 29.3 1.0 CG A:TYR353 4.9 33.3 1.0 CB C:GLU357 4.9 25.9 1.0 CG C:LEU356 5.0 29.2 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Palmitoylated Human TEAD3 Transcription Factor within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca501 b:44.1 occ:1.00 O A:HOH544 2.5 43.9 1.0 CG D:TYR353 3.4 28.0 1.0 CB D:TYR353 3.4 27.6 1.0 CD2 D:TYR353 3.7 27.7 1.0 O D:HOH611 3.8 45.0 1.0 CD1 D:TYR353 3.8 28.9 1.0 N A:ASN358 3.8 34.7 1.0 CA A:GLU357 3.9 35.0 1.0 O A:LEU356 4.0 32.8 1.0 CE2 C:TYR353 4.0 33.2 1.0 CD2 C:TYR353 4.1 27.0 1.0 C A:GLU357 4.4 35.7 1.0 CE2 D:TYR353 4.4 28.3 1.0 N A:GLU357 4.5 30.9 1.0 CE1 D:TYR353 4.5 34.1 1.0 C A:LEU356 4.5 30.2 1.0 CZ C:TYR353 4.6 34.9 1.0 O A:HOH508 4.6 33.8 1.0 CG C:TYR353 4.8 24.9 1.0 CB A:GLU357 4.8 32.6 1.0 CZ D:TYR353 4.8 33.6 1.0 CA D:TYR353 4.9 26.9 1.0 O D:ALA354 4.9 30.2 1.0 CG A:GLU357 4.9 36.3 1.0 CA A:ASN358 4.9 37.1 1.0

C.L.Noland, S.Gierke, P.D.Schnier, J.Murray, W.N.Sandoval, M.Sagolla, A.Dey, R.N.Hannoush, W.J.Fairbrother, C.N.Cunningham. Palmitoylation of Tead Transcription Factors Is Required For Their Stability and Function in Hippo Pathway Signaling. Structure V. 24 179 2016.
ISSN: ISSN 0969-2126
PubMed: 26724994
DOI: 10.1016/J.STR.2015.11.005