Calcium in PDB 5h8h: Structure of the Human GLUN1/GLUN2A Lbd in Complex with GNE3419

The structure of Structure of the Human GLUN1/GLUN2A Lbd in Complex with GNE3419, PDB code: 5h8h was solved by H.J.A.Wallweber, P.J.Lupardus, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.10 / 2.23
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.591, 89.659, 122.439, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 22.7

The binding sites of Calcium atom in the Structure of the Human GLUN1/GLUN2A Lbd in Complex with GNE3419 (pdb code 5h8h). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure of the Human GLUN1/GLUN2A Lbd in Complex with GNE3419, PDB code: 5h8h:

Calcium binding site 1 out of 1 in the Structure of the Human GLUN1/GLUN2A Lbd in Complex with GNE3419


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the Human GLUN1/GLUN2A Lbd in Complex with GNE3419 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca301 b:76.7 occ:1.00 O B:HOH428 3.9 57.3 1.0 CD B:PRO260 3.9 60.2 1.0 NE1 B:TRP261 4.1 66.8 1.0 CD1 B:TRP261 4.3 67.0 1.0 OD1 B:ASP120 4.3 51.6 1.0 CG B:PRO260 4.5 64.7 1.0 CG B:ASP120 4.6 53.0 1.0 CB B:ASP120 4.6 43.8 1.0 NH2 B:ARG256 4.6 42.7 1.0 CD1 B:LEU7 4.7 53.8 1.0 OG B:SER259 4.9 62.1 1.0

D.H.Hackos, P.J.Lupardus, T.Grand, Y.Chen, T.M.Wang, P.Reynen, A.Gustafson, H.J.Wallweber, M.Volgraf, B.D.Sellers, J.B.Schwarz, P.Paoletti, M.Sheng, Q.Zhou, J.E.Hanson. Positive Allosteric Modulators of GLUN2A-Containing Nmdars with Distinct Modes of Action and Impacts on Circuit Function. Neuron V. 89 983 2016.
ISSN: ISSN 1097-4199
PubMed: 26875626
DOI: 10.1016/J.NEURON.2016.01.016