Calcium in PDB 5h9o: Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose
Enzymatic activity of Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose
All present enzymatic activity of Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose:
3.2.1.84;
Protein crystallography data
The structure of Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose, PDB code: 5h9o
was solved by
A.T.Caputo,
P.Roversi,
D.S.Alonzi,
J.L.Kiappes,
N.Zitzmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
87.66 /
2.37
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
102.145,
170.741,
125.989,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
22.1 /
25.3
|
Calcium Binding Sites:
The binding sites of Calcium atom in the Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose
(pdb code 5h9o). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the
Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose, PDB code: 5h9o:
Jump to Calcium binding site number:
1;
2;
3;
4;
Calcium binding site 1 out
of 4 in 5h9o
Go back to
Calcium Binding Sites List in 5h9o
Calcium binding site 1 out
of 4 in the Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca202
b:27.4
occ:1.00
|
OD1
|
B:ASP53
|
2.2
|
33.3
|
1.0
|
|
O
|
B:TYR55
|
2.3
|
28.8
|
1.0
|
|
O
|
B:GLN50
|
2.3
|
43.4
|
1.0
|
|
OD2
|
B:ASP57
|
2.3
|
20.3
|
1.0
|
|
OD2
|
B:ASP63
|
2.4
|
32.7
|
1.0
|
|
OE2
|
B:GLU64
|
2.4
|
18.6
|
1.0
|
|
H
|
B:TYR55
|
3.3
|
24.0
|
1.0
|
|
H
|
B:ASP53
|
3.3
|
25.6
|
1.0
|
|
H
|
B:ASP57
|
3.3
|
30.0
|
1.0
|
|
HH11
|
A:ARG951
|
3.4
|
28.6
|
1.0
|
|
HG2
|
B:GLU64
|
3.4
|
27.2
|
1.0
|
|
CD
|
B:GLU64
|
3.4
|
30.0
|
1.0
|
|
HB3
|
B:GLN50
|
3.4
|
44.7
|
1.0
|
|
C
|
B:GLN50
|
3.4
|
43.9
|
1.0
|
|
CG
|
B:ASP53
|
3.4
|
33.3
|
1.0
|
|
C
|
B:TYR55
|
3.5
|
26.9
|
1.0
|
|
CG
|
B:ASP57
|
3.5
|
29.9
|
1.0
|
|
HB2
|
B:ASP57
|
3.5
|
32.3
|
1.0
|
|
CG
|
B:ASP63
|
3.6
|
29.1
|
1.0
|
|
HB2
|
B:ASP63
|
3.7
|
31.4
|
1.0
|
|
HB3
|
B:TYR55
|
3.8
|
22.3
|
1.0
|
|
CG
|
B:GLU64
|
3.9
|
26.8
|
1.0
|
|
HA
|
B:CYS56
|
4.0
|
27.7
|
1.0
|
|
N
|
B:ASP57
|
4.0
|
30.1
|
1.0
|
|
HA
|
B:GLN50
|
4.0
|
42.5
|
1.0
|
|
CB
|
B:ASP57
|
4.0
|
30.6
|
1.0
|
|
HG3
|
B:GLU64
|
4.1
|
27.3
|
1.0
|
|
HA
|
B:VAL51
|
4.1
|
37.1
|
1.0
|
|
NH1
|
A:ARG951
|
4.2
|
29.6
|
1.0
|
|
CA
|
B:GLN50
|
4.2
|
42.7
|
1.0
|
|
OD2
|
B:ASP53
|
4.2
|
28.8
|
1.0
|
|
HD1
|
B:TYR55
|
4.2
|
24.4
|
1.0
|
|
N
|
B:TYR55
|
4.2
|
22.7
|
1.0
|
|
HD12
|
B:ILE46
|
4.2
|
53.8
|
1.0
|
|
CB
|
B:ASP63
|
4.2
|
30.9
|
1.0
|
|
HH12
|
A:ARG951
|
4.2
|
30.5
|
1.0
|
|
CB
|
B:GLN50
|
4.3
|
43.9
|
1.0
|
|
CA
|
B:TYR55
|
4.3
|
22.5
|
1.0
|
|
N
|
B:ASP53
|
4.3
|
25.4
|
1.0
|
|
N
|
B:CYS56
|
4.4
|
26.7
|
1.0
|
|
OE1
|
B:GLU64
|
4.4
|
27.4
|
1.0
|
|
H
|
B:ASN52
|
4.4
|
28.7
|
1.0
|
|
CB
|
B:ASP53
|
4.5
|
24.5
|
1.0
|
|
N
|
B:VAL51
|
4.5
|
38.2
|
1.0
|
|
OD1
|
B:ASP57
|
4.5
|
28.0
|
1.0
|
|
HB3
|
B:ASP53
|
4.5
|
24.4
|
1.0
|
|
CA
|
B:CYS56
|
4.5
|
27.2
|
1.0
|
|
OD1
|
B:ASP63
|
4.5
|
25.4
|
1.0
|
|
CB
|
B:TYR55
|
4.6
|
22.1
|
1.0
|
|
C
|
B:CYS56
|
4.6
|
33.3
|
1.0
|
|
O
|
B:ASP63
|
4.6
|
32.9
|
1.0
|
|
CA
|
B:ASP57
|
4.7
|
29.9
|
1.0
|
|
CA
|
B:VAL51
|
4.7
|
36.3
|
1.0
|
|
N
|
B:ASN52
|
4.8
|
28.1
|
1.0
|
|
H
|
B:ASP54
|
4.8
|
27.8
|
1.0
|
|
CA
|
B:ASP53
|
4.8
|
24.0
|
1.0
|
|
HD11
|
B:ILE46
|
4.8
|
53.3
|
1.0
|
|
CD1
|
B:ILE46
|
4.9
|
53.6
|
1.0
|
|
C
|
B:ASP63
|
4.9
|
34.9
|
1.0
|
|
N
|
B:ASP54
|
4.9
|
28.4
|
1.0
|
|
HB2
|
B:GLN50
|
4.9
|
44.1
|
1.0
|
|
HB3
|
B:ASP63
|
4.9
|
32.1
|
1.0
|
|
C
|
B:ASP53
|
4.9
|
29.0
|
1.0
|
|
HB3
|
B:ASP57
|
5.0
|
28.8
|
1.0
|
|
HG2
|
B:GLN50
|
5.0
|
42.6
|
1.0
|
|
Calcium binding site 2 out
of 4 in 5h9o
Go back to
Calcium Binding Sites List in 5h9o
Calcium binding site 2 out
of 4 in the Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca203
b:24.2
occ:1.00
|
OE2
|
B:GLU105
|
2.2
|
23.6
|
1.0
|
|
O
|
B:ARG91
|
2.2
|
29.3
|
1.0
|
|
OD1
|
B:ASP94
|
2.3
|
13.5
|
1.0
|
|
O
|
B:VAL96
|
2.3
|
32.2
|
1.0
|
|
OD2
|
B:ASP98
|
2.3
|
25.8
|
1.0
|
|
OD2
|
B:ASP104
|
2.3
|
31.3
|
1.0
|
|
H
|
B:ASP94
|
3.1
|
15.8
|
1.0
|
|
H
|
B:VAL96
|
3.2
|
25.9
|
1.0
|
|
CD
|
B:GLU105
|
3.2
|
38.2
|
1.0
|
|
H
|
B:ASP98
|
3.3
|
31.1
|
1.0
|
|
CG
|
B:ASP94
|
3.3
|
21.0
|
1.0
|
|
HG2
|
B:GLU105
|
3.4
|
38.1
|
1.0
|
|
HB2
|
B:ASP104
|
3.4
|
32.1
|
1.0
|
|
C
|
B:ARG91
|
3.4
|
27.5
|
1.0
|
|
HB3
|
B:ARG91
|
3.4
|
23.1
|
1.0
|
|
CG
|
B:ASP104
|
3.5
|
35.3
|
1.0
|
|
C
|
B:VAL96
|
3.5
|
32.4
|
1.0
|
|
CG
|
B:ASP98
|
3.5
|
30.7
|
1.0
|
|
HB2
|
B:ASP98
|
3.6
|
31.7
|
1.0
|
|
HB
|
B:VAL96
|
3.6
|
27.4
|
1.0
|
|
CG
|
B:GLU105
|
3.8
|
38.1
|
1.0
|
|
OD2
|
B:ASP94
|
3.9
|
26.3
|
1.0
|
|
H
|
B:ASN93
|
3.9
|
16.5
|
1.0
|
|
HA
|
B:ARG91
|
4.0
|
22.7
|
1.0
|
|
CB
|
B:ASP104
|
4.0
|
31.6
|
1.0
|
|
N
|
B:VAL96
|
4.0
|
24.8
|
1.0
|
|
N
|
B:ASP98
|
4.1
|
31.2
|
1.0
|
|
CB
|
B:ASP98
|
4.1
|
31.6
|
1.0
|
|
HA
|
B:VAL92
|
4.1
|
24.1
|
1.0
|
|
HH21
|
A:ARG840
|
4.1
|
24.4
|
1.0
|
|
N
|
B:ASP94
|
4.1
|
15.4
|
1.0
|
|
CA
|
B:ARG91
|
4.1
|
24.3
|
1.0
|
|
CA
|
B:VAL96
|
4.2
|
23.6
|
1.0
|
|
HG3
|
B:GLU105
|
4.2
|
39.0
|
1.0
|
|
CB
|
B:ARG91
|
4.2
|
23.8
|
1.0
|
|
OE1
|
B:GLU105
|
4.3
|
22.5
|
1.0
|
|
HA
|
B:CYS97
|
4.3
|
32.3
|
1.0
|
|
CB
|
B:VAL96
|
4.4
|
25.7
|
1.0
|
|
N
|
B:ASN93
|
4.4
|
18.2
|
1.0
|
|
HD12
|
B:ILE87
|
4.4
|
32.8
|
1.0
|
|
N
|
B:VAL92
|
4.4
|
22.6
|
1.0
|
|
CB
|
B:ASP94
|
4.4
|
15.6
|
1.0
|
|
H
|
B:GLY95
|
4.5
|
25.4
|
1.0
|
|
OD1
|
B:ASP104
|
4.5
|
33.5
|
1.0
|
|
OD1
|
B:ASP98
|
4.5
|
31.9
|
1.0
|
|
N
|
B:CYS97
|
4.5
|
32.4
|
1.0
|
|
HH22
|
A:ARG840
|
4.6
|
25.2
|
1.0
|
|
O
|
B:ASP104
|
4.6
|
25.8
|
1.0
|
|
HG12
|
B:VAL96
|
4.6
|
26.1
|
1.0
|
|
CA
|
B:VAL92
|
4.6
|
23.7
|
1.0
|
|
NH2
|
A:ARG840
|
4.7
|
24.9
|
1.0
|
|
CA
|
B:ASP94
|
4.7
|
14.5
|
1.0
|
|
C
|
B:ASP104
|
4.7
|
31.0
|
1.0
|
|
CA
|
B:ASP98
|
4.7
|
30.6
|
1.0
|
|
HB3
|
B:ASP94
|
4.7
|
15.5
|
1.0
|
|
HB3
|
B:ASP104
|
4.7
|
31.3
|
1.0
|
|
N
|
B:GLY95
|
4.7
|
24.6
|
1.0
|
|
CA
|
B:CYS97
|
4.8
|
33.1
|
1.0
|
|
C
|
B:CYS97
|
4.8
|
34.7
|
1.0
|
|
C
|
B:VAL92
|
4.8
|
25.8
|
1.0
|
|
HD11
|
B:ILE87
|
4.8
|
31.2
|
1.0
|
|
HB2
|
B:ARG91
|
4.9
|
22.8
|
1.0
|
|
HA
|
B:ASN93
|
4.9
|
20.2
|
1.0
|
|
C
|
B:ASP94
|
5.0
|
24.2
|
1.0
|
|
Calcium binding site 3 out
of 4 in 5h9o
Go back to
Calcium Binding Sites List in 5h9o
Calcium binding site 3 out
of 4 in the Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca201
b:25.9
occ:1.00
|
OE2
|
D:GLU64
|
2.3
|
56.2
|
1.0
|
|
O
|
D:TYR55
|
2.3
|
29.9
|
1.0
|
|
OD2
|
D:ASP63
|
2.3
|
39.8
|
1.0
|
|
O
|
D:GLN50
|
2.4
|
37.0
|
1.0
|
|
OD1
|
D:ASP53
|
2.4
|
23.7
|
1.0
|
|
OD2
|
D:ASP57
|
2.8
|
41.1
|
1.0
|
|
HG2
|
D:GLU64
|
3.1
|
24.1
|
1.0
|
|
H
|
D:ASP57
|
3.3
|
34.1
|
1.0
|
|
CD
|
D:GLU64
|
3.3
|
47.9
|
1.0
|
|
H
|
D:ASP53
|
3.3
|
23.6
|
1.0
|
|
HB2
|
D:ASP57
|
3.4
|
37.9
|
1.0
|
|
HB2
|
D:ASP63
|
3.4
|
35.6
|
1.0
|
|
H
|
D:TYR55
|
3.4
|
26.6
|
1.0
|
|
CG
|
D:ASP63
|
3.4
|
34.1
|
1.0
|
|
C
|
D:GLN50
|
3.5
|
37.8
|
1.0
|
|
C
|
D:TYR55
|
3.5
|
31.3
|
1.0
|
|
HH11
|
C:ARG951
|
3.5
|
19.9
|
1.0
|
|
HB3
|
D:GLN50
|
3.6
|
36.9
|
1.0
|
|
CG
|
D:ASP53
|
3.7
|
27.2
|
1.0
|
|
CG
|
D:GLU64
|
3.7
|
24.6
|
1.0
|
|
CG
|
D:ASP57
|
3.8
|
40.8
|
1.0
|
|
HA
|
D:CYS56
|
3.8
|
30.8
|
1.0
|
|
HG3
|
D:GLU64
|
3.9
|
25.2
|
1.0
|
|
N
|
D:ASP57
|
3.9
|
34.2
|
1.0
|
|
CB
|
D:ASP63
|
4.0
|
35.1
|
1.0
|
|
CB
|
D:ASP57
|
4.0
|
37.0
|
1.0
|
|
HA
|
D:VAL51
|
4.1
|
32.3
|
1.0
|
|
HA
|
D:GLN50
|
4.1
|
36.0
|
1.0
|
|
HB3
|
D:TYR55
|
4.1
|
25.0
|
1.0
|
|
HD12
|
D:ILE46
|
4.1
|
42.8
|
1.0
|
|
CA
|
D:GLN50
|
4.2
|
35.8
|
1.0
|
|
N
|
D:ASP53
|
4.3
|
24.4
|
1.0
|
|
H
|
D:ASN52
|
4.3
|
24.0
|
1.0
|
|
N
|
D:TYR55
|
4.3
|
25.3
|
1.0
|
|
NH1
|
C:ARG951
|
4.3
|
20.7
|
1.0
|
|
OE1
|
D:GLU64
|
4.3
|
33.5
|
1.0
|
|
HD1
|
D:TYR55
|
4.3
|
25.0
|
1.0
|
|
N
|
D:CYS56
|
4.4
|
30.8
|
1.0
|
|
CB
|
D:GLN50
|
4.4
|
36.3
|
1.0
|
|
CA
|
D:TYR55
|
4.4
|
24.9
|
1.0
|
|
CA
|
D:CYS56
|
4.4
|
30.8
|
1.0
|
|
HH12
|
C:ARG951
|
4.4
|
20.6
|
1.0
|
|
OD2
|
D:ASP53
|
4.4
|
39.9
|
1.0
|
|
OD1
|
D:ASP63
|
4.4
|
30.1
|
1.0
|
|
N
|
D:VAL51
|
4.5
|
33.2
|
1.0
|
|
O
|
D:ASP63
|
4.5
|
33.5
|
1.0
|
|
C
|
D:CYS56
|
4.5
|
34.6
|
1.0
|
|
CB
|
D:ASP53
|
4.6
|
24.5
|
1.0
|
|
CA
|
D:ASP57
|
4.6
|
36.0
|
1.0
|
|
HB3
|
D:ASP53
|
4.6
|
25.2
|
1.0
|
|
N
|
D:ASN52
|
4.6
|
25.1
|
1.0
|
|
HD11
|
D:ILE46
|
4.7
|
43.2
|
1.0
|
|
HB3
|
D:ASP63
|
4.7
|
35.9
|
1.0
|
|
CA
|
D:VAL51
|
4.7
|
31.2
|
1.0
|
|
C
|
D:ASP63
|
4.7
|
35.5
|
1.0
|
|
CD1
|
D:ILE46
|
4.8
|
43.2
|
1.0
|
|
CB
|
D:TYR55
|
4.8
|
25.1
|
1.0
|
|
H
|
D:ASP54
|
4.8
|
27.6
|
1.0
|
|
HD13
|
D:ILE46
|
4.8
|
42.6
|
1.0
|
|
OD1
|
D:ASP57
|
4.8
|
43.1
|
1.0
|
|
CA
|
D:ASP53
|
4.9
|
23.9
|
1.0
|
|
HB3
|
D:ASP57
|
5.0
|
37.0
|
1.0
|
|
C
|
D:VAL51
|
5.0
|
31.6
|
1.0
|
|
Calcium binding site 4 out
of 4 in 5h9o
Go back to
Calcium Binding Sites List in 5h9o
Calcium binding site 4 out
of 4 in the Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Complex of Murine Endoplasmic Reticulum Alpha-Glucosidase II with D- Glucose within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca202
b:23.8
occ:1.00
|
OE2
|
D:GLU105
|
2.2
|
16.0
|
1.0
|
|
OD2
|
D:ASP104
|
2.2
|
32.3
|
1.0
|
|
O
|
D:ARG91
|
2.3
|
32.5
|
1.0
|
|
OD2
|
D:ASP98
|
2.3
|
29.8
|
1.0
|
|
O
|
D:VAL96
|
2.3
|
32.4
|
1.0
|
|
OD1
|
D:ASP94
|
2.4
|
23.3
|
1.0
|
|
H
|
D:ASP98
|
3.2
|
33.4
|
1.0
|
|
H
|
D:ASP94
|
3.3
|
27.6
|
1.0
|
|
CD
|
D:GLU105
|
3.3
|
20.3
|
1.0
|
|
HB2
|
D:ASP104
|
3.3
|
32.1
|
1.0
|
|
H
|
D:VAL96
|
3.3
|
27.7
|
1.0
|
|
HG2
|
D:GLU105
|
3.3
|
25.9
|
1.0
|
|
CG
|
D:ASP104
|
3.4
|
35.5
|
1.0
|
|
HB3
|
D:ARG91
|
3.4
|
31.2
|
1.0
|
|
C
|
D:ARG91
|
3.4
|
33.7
|
1.0
|
|
CG
|
D:ASP98
|
3.4
|
29.9
|
1.0
|
|
HB2
|
D:ASP98
|
3.5
|
33.0
|
1.0
|
|
CG
|
D:ASP94
|
3.5
|
24.8
|
1.0
|
|
C
|
D:VAL96
|
3.5
|
32.3
|
1.0
|
|
HB
|
D:VAL96
|
3.7
|
31.4
|
1.0
|
|
CG
|
D:GLU105
|
3.8
|
26.2
|
1.0
|
|
CB
|
D:ASP104
|
3.9
|
31.6
|
1.0
|
|
CB
|
D:ASP98
|
4.0
|
32.0
|
1.0
|
|
N
|
D:ASP98
|
4.0
|
33.4
|
1.0
|
|
H
|
D:ASN93
|
4.0
|
25.6
|
1.0
|
|
OD2
|
D:ASP94
|
4.0
|
19.8
|
1.0
|
|
HA
|
D:VAL92
|
4.1
|
28.5
|
1.0
|
|
HA
|
D:ARG91
|
4.1
|
29.8
|
1.0
|
|
N
|
D:VAL96
|
4.1
|
27.7
|
1.0
|
|
HH21
|
C:ARG840
|
4.1
|
28.4
|
1.0
|
|
CA
|
D:ARG91
|
4.2
|
29.1
|
1.0
|
|
HG3
|
D:GLU105
|
4.2
|
26.1
|
1.0
|
|
HA
|
D:CYS97
|
4.2
|
28.9
|
1.0
|
|
CA
|
D:VAL96
|
4.2
|
27.0
|
1.0
|
|
N
|
D:ASP94
|
4.2
|
26.5
|
1.0
|
|
CB
|
D:ARG91
|
4.3
|
30.2
|
1.0
|
|
OE1
|
D:GLU105
|
4.3
|
27.1
|
1.0
|
|
HD12
|
D:ILE87
|
4.3
|
40.1
|
1.0
|
|
OD1
|
D:ASP104
|
4.4
|
38.2
|
1.0
|
|
N
|
D:ASN93
|
4.4
|
25.6
|
1.0
|
|
CB
|
D:VAL96
|
4.5
|
30.4
|
1.0
|
|
N
|
D:VAL92
|
4.5
|
30.1
|
1.0
|
|
OD1
|
D:ASP98
|
4.5
|
28.4
|
1.0
|
|
N
|
D:CYS97
|
4.5
|
30.4
|
1.0
|
|
HH22
|
C:ARG840
|
4.5
|
25.7
|
1.0
|
|
O
|
D:ASP104
|
4.5
|
30.8
|
1.0
|
|
H
|
D:GLY95
|
4.5
|
25.9
|
1.0
|
|
CB
|
D:ASP94
|
4.6
|
24.6
|
1.0
|
|
CA
|
D:ASP98
|
4.6
|
32.7
|
1.0
|
|
HB3
|
D:ASP104
|
4.6
|
31.3
|
1.0
|
|
HG12
|
D:VAL96
|
4.6
|
30.0
|
1.0
|
|
C
|
D:ASP104
|
4.6
|
33.3
|
1.0
|
|
NH2
|
C:ARG840
|
4.7
|
26.2
|
1.0
|
|
CA
|
D:VAL92
|
4.7
|
28.8
|
1.0
|
|
CA
|
D:CYS97
|
4.7
|
30.5
|
1.0
|
|
C
|
D:CYS97
|
4.7
|
34.1
|
1.0
|
|
HD11
|
D:ILE87
|
4.7
|
39.0
|
1.0
|
|
N
|
D:GLY95
|
4.8
|
26.8
|
1.0
|
|
CA
|
D:ASP94
|
4.8
|
24.5
|
1.0
|
|
HB3
|
D:ASP94
|
4.8
|
23.3
|
1.0
|
|
C
|
D:VAL92
|
4.8
|
31.2
|
1.0
|
|
HB2
|
D:ARG91
|
4.9
|
30.6
|
1.0
|
|
HB3
|
D:ASP98
|
4.9
|
30.4
|
1.0
|
|
CD1
|
D:ILE87
|
4.9
|
39.6
|
1.0
|
|
CA
|
D:ASP104
|
4.9
|
29.4
|
1.0
|
|
HA
|
D:ASN93
|
5.0
|
27.2
|
1.0
|
|
Reference:
A.T.Caputo,
D.S.Alonzi,
L.Marti,
I.B.Reca,
J.L.Kiappes,
W.B.Struwe,
A.Cross,
S.Basu,
E.D.Lowe,
B.Darlot,
A.Santino,
P.Roversi,
N.Zitzmann.
Structures of Mammalian Er Alpha-Glucosidase II Capture the Binding Modes of Broad-Spectrum Iminosugar Antivirals. Proc.Natl.Acad.Sci.Usa V. 113 E4630 2016.
ISSN: ESSN 1091-6490
PubMed: 27462106
DOI: 10.1073/PNAS.1604463113
Page generated: Sat Dec 12 05:28:12 2020
|
