Calcium in PDB 5iwp: Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium

The structure of Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium, PDB code: 5iwp was solved by K.Saotome, A.K.Singh, M.V.Yelshanskaya, A.I.Sobolevsky, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.56 / 3.65
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	144.350, 144.350, 113.370, 90.00, 90.00, 90.00
R / Rfree (%)	27.3 / 28.3

The binding sites of Calcium atom in the Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium (pdb code 5iwp). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium, PDB code: 5iwp:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca701 b:25.1 occ:0.25 OD2 A:ASP541 2.6 0.3 1.0 CG A:ASP541 2.8 0.9 1.0 OD1 A:ASP541 3.2 87.4 1.0 CB A:ASP541 3.6 0.8 1.0 CA A:ASP541 4.3 0.7 1.0 N A:ASP541 4.6 0.1 1.0

Calcium binding site 2 out of 3 in the Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca702 b:25.1 occ:0.15 OG1 A:THR538 3.8 0.5 1.0 O A:THR538 4.5 0.2 1.0 CB A:THR538 4.6 0.6 1.0

Calcium binding site 3 out of 3 in the Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Transient Receptor Potential (Trp) Channel TRPV6 in the Presence of Calcium within 5.0Å range:

K.Saotome, A.K.Singh, M.V.Yelshanskaya, A.I.Sobolevsky. Crystal Structure of the Epithelial Calcium Channel TRPV6. Nature V. 534 506 2016.
ISSN: ESSN 1476-4687
PubMed: 27296226
DOI: 10.1038/NATURE17975