Calcium in PDB 5j2u: Tubulin-Mmaf Complex

The structure of Tubulin-Mmaf Complex, PDB code: 5j2u was solved by A.B.Waight, K.Bargsten, S.Doronina, M.O.Steinmetz, D.Sussman, A.E.Prota, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.65 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.567, 155.390, 182.524, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 25

The structure of Tubulin-Mmaf Complex also contains other interesting chemical elements:

Magnesium

(Mg)

5 atoms

The binding sites of Calcium atom in the Tubulin-Mmaf Complex (pdb code 5j2u). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Tubulin-Mmaf Complex, PDB code: 5j2u:

Calcium binding site 1 out of 1 in the Tubulin-Mmaf Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Tubulin-Mmaf Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca503 b:0.9 occ:1.00 OE2 A:GLU55 2.2 0.7 1.0 OG1 A:THR41 2.3 0.3 1.0 OE1 A:GLU55 2.4 0.8 1.0 OD1 A:ASP39 2.4 0.4 1.0 OD2 A:ASP39 2.5 0.4 1.0 CD A:GLU55 2.6 0.2 1.0 CG A:ASP39 2.6 0.5 1.0 HZ A:PHE49 2.6 0.1 1.0 O A:THR41 2.7 0.8 1.0 HE1 A:PHE49 3.1 0.7 1.0 HD21 A:ASN50 3.2 0.6 1.0 CZ A:PHE49 3.4 98.4 1.0 C A:THR41 3.5 0.8 1.0 CE1 A:PHE49 3.6 93.0 1.0 CB A:THR41 3.6 0.2 1.0 H A:THR41 3.7 0.4 1.0 NE2 A:HIS61 3.7 98.0 1.0 HB2 A:ASP39 3.8 0.1 1.0 CB A:ASP39 3.9 0.5 1.0 HD2 A:HIS61 3.9 0.7 1.0 CA A:THR41 3.9 0.7 1.0 CG A:GLU55 4.0 99.9 1.0 HB A:THR41 4.0 0.7 1.0 ND2 A:ASN50 4.1 90.5 1.0 N A:THR41 4.1 0.5 1.0 HA3 A:GLY45 4.1 0.4 1.0 CD2 A:HIS61 4.2 92.2 1.0 HG2 A:GLU55 4.2 0.9 1.0 HB3 A:ASP39 4.3 0.1 1.0 HG3 A:GLU55 4.4 0.9 1.0 O A:GLY44 4.4 0.1 1.0 OD1 A:ASN50 4.5 99.8 1.0 N A:ILE42 4.5 0.7 1.0 HA A:ILE42 4.6 0.1 1.0 CE2 A:PHE49 4.6 98.7 1.0 HG21 A:THR41 4.6 0.8 1.0 OD1 A:ASP47 4.6 99.8 1.0 HD22 A:ASN50 4.6 0.6 1.0 C A:GLY44 4.7 0.5 1.0 CG2 A:THR41 4.7 1.0 1.0 CG A:ASN50 4.8 94.0 1.0 HB3 A:GLU55 4.8 1.0 1.0 HA A:THR41 4.9 0.2 1.0 CE1 A:HIS61 4.9 98.1 1.0 H A:LYS40 4.9 0.8 1.0 HE2 A:PHE49 4.9 0.4 1.0 N A:GLY45 4.9 0.2 1.0 CA A:GLY45 4.9 1.0 1.0 CD1 A:PHE49 4.9 92.3 1.0 CA A:ASP39 5.0 1.0 1.0 HB2 A:ASP47 5.0 0.0 1.0 HG23 A:THR41 5.0 0.8 1.0

A.B.Waight, K.Bargsten, S.Doronina, M.O.Steinmetz, D.Sussman, A.E.Prota. Structural Basis of Microtubule Destabilization By Potent Auristatin Anti-Mitotics. Plos One V. 11 60890 2016.
ISSN: ESSN 1932-6203
PubMed: 27518442
DOI: 10.1371/JOURNAL.PONE.0160890