Atomistry » Calcium » PDB 5kaf-5klb » 5kfk
Atomistry »
  Calcium »
    PDB 5kaf-5klb »
      5kfk »

Calcium in PDB 5kfk: Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S

Enzymatic activity of Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S

All present enzymatic activity of Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S:
2.7.7.7;

Protein crystallography data

The structure of Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S, PDB code: 5kfk was solved by Y.Gao, W.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.93 / 1.70
Space group P 61
Cell size a, b, c (Å), α, β, γ (°) 98.270, 98.270, 82.010, 90.00, 90.00, 120.00
R / Rfree (%) 17.2 / 21

Other elements in 5kfk:

The structure of Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S also contains other interesting chemical elements:

Manganese (Mn) 3 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S (pdb code 5kfk). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S, PDB code: 5kfk:

Calcium binding site 1 out of 1 in 5kfk

Go back to Calcium Binding Sites List in 5kfk
Calcium binding site 1 out of 1 in the Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Dna Polymerase Eta-Dna Ternary Complex: Reaction with 10 Mm MN2+ For 300S within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca502

b:12.0
occ:0.05
 MN A:MN503 0.0 12.0 0.9
O5 A:DPO508 2.0 12.6 0.5
O1 A:DPO508 2.0 10.6 0.5
O1B A:DTP507 2.1 10.5 0.5
OD2 A:ASP115 2.2 9.6 1.0
O1G A:DTP507 2.3 13.0 0.5
O1A A:DTP507 2.3 13.7 0.5
OD1 A:ASP13 2.3 12.2 1.0
O A:MET14 2.3 10.6 1.0
OP1 P:DA9 2.4 13.7 0.5
PB A:DTP507 3.1 11.8 0.5
CG A:ASP13 3.1 13.2 1.0
P1 A:DPO508 3.2 11.8 0.5
CG A:ASP115 3.3 12.7 1.0
PA A:DTP507 3.3 9.9 0.5
P2 A:DPO508 3.3 13.8 0.5
O3A A:DTP507 3.4 13.2 0.5
PG A:DTP507 3.4 13.7 0.5
OD2 A:ASP13 3.4 13.6 1.0
C A:MET14 3.5 12.9 1.0
O2 A:DPO508 3.6 13.2 0.5
MN A:MN501 3.6 12.6 1.0
O4 A:DPO508 3.6 11.1 0.5
O3B A:DTP507 3.6 11.1 0.5
OD1 A:ASP115 3.7 10.0 1.0
P P:DA9 3.8 13.4 0.5
O A:HOH690 3.9 28.6 1.0
NZ A:LYS231 3.9 16.1 1.0
C5' A:DTP507 3.9 12.7 0.5
O7 A:DPO508 3.9 11.2 0.5
O2G A:DTP507 4.0 11.1 0.5
N A:MET14 4.0 9.3 1.0
O5' A:DTP507 4.1 12.2 0.5
C5' P:DA9 4.1 12.4 0.5
CA A:MET14 4.2 10.8 1.0
O5' P:DA9 4.3 13.3 0.5
C A:ASP13 4.3 10.2 1.0
N A:CYS16 4.4 10.5 1.0
O P:HOH210 4.4 14.1 1.0
CB A:ASP13 4.4 11.1 1.0
N A:ASP15 4.5 8.6 1.0
O2B A:DTP507 4.5 11.9 0.5
O3 A:DPO508 4.5 11.8 0.5
O6 A:DPO508 4.5 14.0 0.5
CB A:ASP115 4.5 9.7 1.0
O2A A:DTP507 4.5 13.8 0.5
CA A:ASP15 4.5 9.3 1.0
O3G A:DTP507 4.6 14.2 0.5
OP2 P:DA9 4.7 14.4 0.5
O A:ASP13 4.7 11.6 1.0
C A:ASP15 4.7 13.0 1.0
CB A:MET14 4.7 12.7 1.0
N A:PHE17 4.7 8.9 1.0
CE A:LYS231 4.7 23.2 1.0
O3' P:DT8 4.8 13.3 0.5
CA A:ASP13 4.9 11.4 1.0
MN P:MN101 4.9 19.4 0.5
CB A:PHE17 4.9 9.2 1.0
O A:ASP115 5.0 10.1 1.0

Reference:

Y.Gao, W.Yang. Capture of A Third MG2+ Is Essential For Catalyzing Dna Synthesis. Science V. 352 1334 2016.
ISSN: ESSN 1095-9203
PubMed: 27284197
DOI: 10.1126/SCIENCE.AAD9633
Page generated: Mon Jul 15 06:51:19 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy