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Atomistry » Calcium » PDB 5klg-5l0t » 5l0k | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Calcium » PDB 5klg-5l0t » 5l0k » |
Calcium in PDB 5l0k: Crystal Structure of Autotaxin and Compound Pf-8380Enzymatic activity of Crystal Structure of Autotaxin and Compound Pf-8380
All present enzymatic activity of Crystal Structure of Autotaxin and Compound Pf-8380:
3.1.4.39; Protein crystallography data
The structure of Crystal Structure of Autotaxin and Compound Pf-8380, PDB code: 5l0k
was solved by
J.D.Durbin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5l0k:
The structure of Crystal Structure of Autotaxin and Compound Pf-8380 also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structure of Autotaxin and Compound Pf-8380
(pdb code 5l0k). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Autotaxin and Compound Pf-8380, PDB code: 5l0k: Jump to Calcium binding site number: 1; 2; Calcium binding site 1 out of 2 in 5l0kGo back to Calcium Binding Sites List in 5l0k
Calcium binding site 1 out
of 2 in the Crystal Structure of Autotaxin and Compound Pf-8380
Mono view Stereo pair view
Calcium binding site 2 out of 2 in 5l0kGo back to Calcium Binding Sites List in 5l0k
Calcium binding site 2 out
of 2 in the Crystal Structure of Autotaxin and Compound Pf-8380
Mono view Stereo pair view
Reference:
S.B.Jones,
L.A.Pfeifer,
T.J.Bleisch,
T.J.Beauchamp,
J.D.Durbin,
V.J.Klimkowski,
N.E.Hughes,
C.J.Rito,
Y.Dao,
J.M.Gruber,
H.Bui,
M.G.Chambers,
S.Chandrasekhar,
C.Lin,
D.J.Mccann,
D.R.Mudra,
J.L.Oskins,
C.A.Swearingen,
K.Thirunavukkarasu,
B.H.Norman.
Novel Autotaxin Inhibitors For the Treatment of Osteoarthritis Pain: Lead Optimization Via Structure-Based Drug Design. Acs Med.Chem.Lett. V. 7 857 2016.
Page generated: Mon Jul 15 07:10:44 2024
ISSN: ISSN 1948-5875 PubMed: 27660691 DOI: 10.1021/ACSMEDCHEMLETT.6B00207 |
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