Calcium in PDB 5mc9: Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111

The structure of Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111, PDB code: 5mc9 was solved by D.Pulido, E.Hohenester, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.90 / 2.13
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	62.760, 98.360, 135.240, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 23.8

The binding sites of Calcium atom in the Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111 (pdb code 5mc9). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111, PDB code: 5mc9:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca9001 b:0.8 occ:1.00 O A:LEU2190 2.5 37.0 1.0 O A:VAL2247 2.5 36.6 1.0 OD1 A:ASP2249 2.5 70.9 1.0 O A:HOH9308 2.5 65.2 1.0 OD2 A:ASP2173 2.6 36.5 1.0 O A:HOH9225 2.9 40.1 1.0 CG A:ASP2249 3.4 71.4 1.0 H A:ASP2249 3.5 70.1 1.0 C A:LEU2190 3.5 39.5 1.0 CG A:ASP2173 3.7 38.0 1.0 C A:VAL2247 3.7 38.1 1.0 HA3 A:GLY2191 3.8 48.9 1.0 HA A:LEU2248 3.8 54.2 1.0 N A:ASP2249 3.9 58.4 1.0 HB3 A:LEU2190 4.0 40.9 1.0 OD2 A:ASP2249 4.0 71.6 1.0 OD1 A:ASP2173 4.0 40.4 1.0 HA A:LEU2190 4.1 45.3 1.0 HB3 A:SER2245 4.1 52.3 1.0 HB A:VAL2247 4.2 46.4 1.0 CA A:LEU2190 4.3 37.8 1.0 H A:VAL2247 4.3 42.3 1.0 CB A:ASP2249 4.4 71.1 1.0 N A:GLY2191 4.4 43.0 1.0 CA A:LEU2248 4.4 45.1 1.0 C A:LEU2248 4.5 47.3 1.0 HB2 A:ASP2249 4.5 85.3 1.0 N A:LEU2248 4.5 40.9 1.0 CA A:GLY2191 4.5 40.8 1.0 CA A:ASP2249 4.6 65.2 1.0 HA A:ASP2249 4.6 78.2 1.0 CB A:LEU2190 4.6 34.0 1.0 CA A:VAL2247 4.7 38.5 1.0 OG A:SER2245 4.8 47.3 1.0 N A:VAL2247 4.8 35.2 1.0 CB A:VAL2247 4.9 38.7 1.0 HG12 A:VAL2247 4.9 49.8 1.0 HA2 A:GLY2191 4.9 48.9 1.0 CB A:SER2245 4.9 43.6 1.0 CB A:ASP2173 4.9 37.3 1.0 HB3 A:ASP2173 5.0 44.8 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca9002 b:51.2 occ:1.00 O A:LEU2377 2.4 29.1 1.0 O A:ASP2433 2.4 38.9 1.0 OD2 A:ASP2360 2.4 35.4 1.0 OD1 A:ASN2435 2.5 30.5 1.0 O A:HOH9339 2.5 42.3 1.0 O A:HOH9149 2.7 39.0 1.0 H A:ASN2435 3.2 41.4 1.0 CG A:ASN2435 3.5 33.8 1.0 C A:LEU2377 3.5 29.8 1.0 CG A:ASP2360 3.5 37.5 1.0 C A:ASP2433 3.6 35.5 1.0 HB2 A:ASN2435 3.6 39.2 1.0 HB1 A:ALA2431 3.8 48.0 1.0 HB3 A:LEU2377 3.8 34.2 1.0 HA3 A:GLY2378 3.9 55.9 1.0 HB2 A:ASP2433 3.9 51.7 1.0 OD1 A:ASP2360 3.9 41.0 1.0 H A:ASP2433 3.9 52.2 1.0 N A:ASN2435 4.0 34.5 1.0 HA A:LEU2377 4.0 37.0 1.0 CB A:ASN2435 4.0 32.6 1.0 HA A:LEU2434 4.1 41.3 1.0 CA A:LEU2377 4.3 30.9 1.0 O A:HOH9261 4.4 46.1 1.0 CA A:ASP2433 4.4 38.1 1.0 CB A:ASP2433 4.5 43.1 1.0 N A:GLY2378 4.5 44.0 1.0 HB3 A:ASP2433 4.5 51.7 1.0 N A:ASP2433 4.5 43.5 1.0 N A:LEU2434 4.5 31.5 1.0 CB A:LEU2377 4.5 28.5 1.0 ND2 A:ASN2435 4.5 33.9 1.0 CA A:GLY2378 4.6 46.6 1.0 CA A:LEU2434 4.6 34.4 1.0 CB A:ALA2431 4.7 40.0 1.0 CA A:ASN2435 4.7 33.4 1.0 HD21 A:ASN2435 4.7 40.7 1.0 HB3 A:ASP2360 4.7 41.5 1.0 CB A:ASP2360 4.8 34.5 1.0 C A:LEU2434 4.8 33.8 1.0 HB2 A:ALA2431 4.8 48.0 1.0 HB3 A:ASN2435 4.9 39.2 1.0 HB2 A:LEU2377 5.0 34.2 1.0

D.Pulido, S.A.Hussain, E.Hohenester. Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111. Structure V. 25 530 2017.
ISSN: ISSN 1878-4186
PubMed: 28132784
DOI: 10.1016/J.STR.2017.01.002