Calcium in PDB 5ov7: Tubulin - Rigosertib Complex

The structure of Tubulin - Rigosertib Complex, PDB code: 5ov7 was solved by G.Menchon, A.E.Prota, M.Steinmetz, M.Jost, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.08 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.732, 156.765, 182.629, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 23.5

The structure of Tubulin - Rigosertib Complex also contains other interesting chemical elements:

Magnesium

(Mg)

5 atoms

The binding sites of Calcium atom in the Tubulin - Rigosertib Complex (pdb code 5ov7). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Tubulin - Rigosertib Complex, PDB code: 5ov7:

Calcium binding site 1 out of 1 in the Tubulin - Rigosertib Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Tubulin - Rigosertib Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca503 b:91.1 occ:1.00 OG1 A:THR41 2.2 1.0 1.0 OE2 A:GLU55 2.3 0.7 1.0 O A:GLY44 2.5 0.8 1.0 OD2 A:ASP39 2.6 96.7 1.0 O A:THR41 2.6 0.9 1.0 OD1 A:ASP39 2.6 93.3 1.0 OE1 A:GLU55 2.8 0.2 1.0 CD A:GLU55 2.9 1.0 1.0 CG A:ASP39 3.0 97.6 1.0 C A:GLY44 3.4 0.4 1.0 CB A:THR41 3.4 0.9 1.0 C A:THR41 3.5 0.2 1.0 CA A:GLY45 3.8 0.4 1.0 CA A:THR41 3.9 0.5 1.0 N A:GLY45 4.0 0.9 1.0 OD2 A:ASP47 4.1 90.9 1.0 N A:THR41 4.2 0.9 1.0 CZ A:PHE49 4.3 73.8 1.0 CG A:GLU55 4.4 0.0 1.0 OD1 A:ASN50 4.4 95.6 1.0 CB A:ASP39 4.5 0.9 1.0 N A:GLY44 4.5 0.3 1.0 CA A:GLY44 4.5 0.5 1.0 NE2 A:HIS61 4.6 91.3 1.0 ND2 A:ASN50 4.6 90.1 1.0 CG2 A:THR41 4.6 0.4 1.0 N A:ILE42 4.7 0.2 1.0 CE1 A:PHE49 4.8 77.2 1.0 CG A:ASN50 5.0 84.9 1.0

M.Jost, Y.Chen, L.A.Gilbert, M.A.Horlbeck, L.Krenning, G.Menchon, A.Rai, M.Y.Cho, J.J.Stern, A.E.Prota, M.Kampmann, A.Akhmanova, M.O.Steinmetz, M.E.Tanenbaum, J.S.Weissman. Combined Crispri/A-Based Chemical Genetic Screens Reveal That Rigosertib Is A Microtubule-Destabilizing Agent. Mol. Cell V. 68 210 2017.
ISSN: ISSN 1097-4164
PubMed: 28985505
DOI: 10.1016/J.MOLCEL.2017.09.012