Calcium in PDB 5s4s: Tubulin-Z240297434-Complex

The structure of Tubulin-Z240297434-Complex, PDB code: 5s4s was solved by T.Muehlethaler, D.Gioia, A.E.Prota, M.E.Sharpe, A.Cavalli, M.O.Steinmetz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	86.68 / 2.35
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	105.55, 164.17, 173.36, 90, 90, 90
R / Rfree (%)	24.4 / 28.4

The structure of Tubulin-Z240297434-Complex also contains other interesting chemical elements:

Magnesium

(Mg)

5 atoms

The binding sites of Calcium atom in the Tubulin-Z240297434-Complex (pdb code 5s4s). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Tubulin-Z240297434-Complex, PDB code: 5s4s:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Tubulin-Z240297434-Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Tubulin-Z240297434-Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca503 b:138.0 occ:1.00 OE2 A:GLU196 4.2 105.8 1.0

Calcium binding site 2 out of 3 in the Tubulin-Z240297434-Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Tubulin-Z240297434-Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca503 b:110.5 occ:1.00 OE1 B:GLU113 2.4 79.2 1.0 CD B:GLU113 3.2 78.6 1.0 OE2 B:GLU113 3.3 86.5 1.0 OE1 B:GLU110 4.5 64.2 1.0 CG B:GLU113 4.7 69.1 1.0

Calcium binding site 3 out of 3 in the Tubulin-Z240297434-Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Tubulin-Z240297434-Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca503 b:73.2 occ:1.00 OD2 C:ASP39 2.4 73.5 1.0 OE1 C:GLU55 2.4 72.9 1.0 OE2 C:GLU55 2.4 69.0 1.0 O C:HOH614 2.4 77.3 1.0 OG1 C:THR41 2.4 75.4 1.0 O C:THR41 2.5 79.0 1.0 O C:GLY44 2.6 84.4 1.0 OD1 C:ASP39 2.7 75.9 1.0 CD C:GLU55 2.7 74.3 1.0 CG C:ASP39 2.9 76.7 1.0 C C:THR41 3.5 81.4 1.0 C C:GLY44 3.6 83.9 1.0 CB C:THR41 3.6 80.6 1.0 CA C:THR41 4.0 77.6 1.0 CG C:GLU55 4.2 67.0 1.0 CA C:GLY45 4.3 85.9 1.0 N C:THR41 4.3 82.4 1.0 N C:GLY45 4.3 84.7 1.0 OD1 C:ASN50 4.3 72.8 1.0 OD2 C:ASP47 4.4 71.7 1.0 CZ C:PHE49 4.4 67.7 1.0 CB C:ASP39 4.4 75.9 1.0 N C:GLY44 4.5 82.2 1.0 CA C:GLY44 4.5 86.4 1.0 N C:ILE42 4.6 77.2 1.0 NE2 C:HIS61 4.7 67.1 1.0 CE1 C:PHE49 4.8 64.6 1.0 CG2 C:THR41 4.8 70.9 1.0 ND2 C:ASN50 4.9 69.9 1.0

T.Muhlethaler, D.Gioia, A.E.Prota, M.E.Sharpe, A.Cavalli, M.O.Steinmetz. Comprehensive Analysis of Binding Sites in Tubulin. Angew.Chem.Int.Ed.Engl. V. 60 13331 2021.
ISSN: ESSN 1521-3773
PubMed: 33951246
DOI: 10.1002/ANIE.202100273