Calcium in PDB 5w0r: Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid

All present enzymatic activity of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid:
3.5.4.38;

The structure of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid, PDB code: 5w0r was solved by Q.Qiao, L.Wang, H.Wu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.81 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.960, 179.070, 188.080, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 23.9

The structure of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid also contains other interesting chemical elements:

Arsenic	(As)	2 atoms
Zinc	(Zn)	2 atoms

The binding sites of Calcium atom in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid (pdb code 5w0r). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid, PDB code: 5w0r:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca2003 b:58.3 occ:1.00 O B:HOH2160 2.4 37.1 1.0 O B:ALA370 2.4 28.2 1.0 O B:THR367 2.6 32.7 1.0 O B:HOH2155 2.8 43.0 1.0 C B:ALA370 3.6 28.5 1.0 C B:THR367 3.8 33.2 1.0 O B:ASN368 3.9 30.8 1.0 O B:PHE1046 4.0 27.0 1.0 CA B:ALA371 4.2 30.4 1.0 C B:ASN368 4.3 31.0 1.0 O B:HOH2201 4.3 45.9 1.0 N B:ALA371 4.3 29.8 1.0 N B:GLU372 4.3 34.2 1.0 OD1 B:ASP1045 4.4 36.8 1.0 CA B:ASN368 4.5 32.7 1.0 O B:HOH2200 4.6 48.3 1.0 C B:ALA371 4.6 32.5 1.0 N B:ALA370 4.6 28.4 1.0 N B:ASN368 4.6 33.5 1.0 CA B:ALA370 4.7 28.2 1.0 CG2 B:THR367 4.8 34.2 1.0 CA B:THR367 4.9 34.2 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) in Complex with Cacodylic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2003 b:77.4 occ:1.00 O A:PHE1046 2.9 39.8 1.0 O A:ALA370 3.1 47.2 1.0 O A:ASN368 3.4 53.8 1.0 O A:THR367 3.5 56.9 1.0 OD1 A:ASP1045 3.5 52.0 1.0 C A:ASN368 4.1 53.2 1.0 C A:PHE1046 4.1 39.1 1.0 OE2 A:GLU372 4.2 40.9 0.5 C A:ALA370 4.3 48.2 1.0 CG A:GLU372 4.4 41.5 0.5 CA A:ASN368 4.5 54.3 1.0 OH A:TYR1031 4.5 33.7 1.0 C A:THR367 4.6 55.5 1.0 CD A:GLU372 4.6 41.8 0.5 CG A:ASP1045 4.7 51.9 1.0 N A:PHE1046 4.8 45.5 1.0 N A:ALA370 4.9 50.6 1.0 O A:HOH2111 4.9 51.2 1.0 CA A:GLY1047 4.9 34.7 1.0

Q.Qiao, L.Wang, F.L.Meng, J.K.Hwang, F.W.Alt, H.Wu. Aid Recognizes Structured Dna For Class Switch Recombination. Mol. Cell V. 67 361 2017.
ISSN: ISSN 1097-4164
PubMed: 28757211
DOI: 10.1016/J.MOLCEL.2017.06.034