Calcium in PDB 5w4s: Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide

All present enzymatic activity of Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide:
2.7.11.13;

The binding sites of Calcium atom in the Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide (pdb code 5w4s). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide, PDB code: 5w4s:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca301 b:0.6 occ:1.00 OD2 A:ASP193 2.2 0.7 1.0 OD1 A:ASP246 2.3 0.7 1.0 OD1 A:ASP248 2.3 0.6 1.0 OD2 A:ASP187 2.3 0.9 1.0 O A:TRP247 2.3 0.6 1.0 OD1 A:ASP187 2.5 0.6 1.0 OD2 A:ASP246 2.7 0.7 1.0 CG A:ASP187 2.7 0.6 1.0 CG A:ASP246 2.8 0.5 1.0 HA A:ASP248 3.1 0.7 1.0 H A:ASP193 3.1 0.6 1.0 CG A:ASP193 3.4 0.6 1.0 C A:TRP247 3.4 0.5 1.0 CG A:ASP248 3.5 0.6 1.0 CA A:CA302 3.6 0.6 1.0 OD1 A:ASP193 3.9 0.9 1.0 CA A:ASP248 3.9 0.6 1.0 HA A:SER192 4.0 0.7 1.0 N A:ASP193 4.0 0.5 1.0 N A:ASP248 4.1 0.5 1.0 N A:TRP247 4.2 0.5 1.0 C A:ASP246 4.2 0.5 1.0 CB A:ASP246 4.3 0.6 1.0 CB A:ASP187 4.3 0.6 1.0 CB A:ASP248 4.4 0.7 1.0 O A:ASP193 4.4 0.5 1.0 OD2 A:ASP248 4.4 0.8 1.0 O A:ASP246 4.4 0.5 1.0 CA A:TRP247 4.4 0.5 1.0 H A:TRP247 4.4 0.6 1.0 CB A:ASP193 4.6 0.6 1.0 CA A:ASP193 4.7 0.5 1.0 HB3 A:ASP187 4.7 0.6 1.0 HB2 A:ASP187 4.7 0.6 1.0 CA A:ASP246 4.7 0.5 1.0 C A:ASP193 4.7 0.5 1.0 HB2 A:ASP246 4.8 0.7 1.0 HD13 A:LEU191 4.8 2.2 1.0 HA A:ASP246 4.8 0.6 1.0 HB3 A:ASP246 4.8 0.6 1.0 O A:MET186 4.9 0.6 1.0 HA A:ASP187 4.9 0.6 1.0 CA A:SER192 4.9 0.6 1.0 HB3 A:TRP247 5.0 0.8 1.0 H A:ASP248 5.0 0.5 1.0 C A:SER192 5.0 0.6 1.0

Calcium binding site 2 out of 2 in the Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Solution Structure of C2 Domain From Protein Kinase C Alpha in Ternary Complex with Calcium and V5-Phm Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca302 b:0.6 occ:1.00 OD2 A:ASP254 2.2 0.7 1.0 OD1 A:ASP187 2.3 0.6 1.0 OD2 A:ASP246 2.3 0.7 1.0 OD2 A:ASP248 2.3 0.8 1.0 OD1 A:ASP248 2.4 0.6 1.0 O A:MET186 2.4 0.6 1.0 CG A:ASP248 2.7 0.6 1.0 CG A:ASP254 3.2 0.7 1.0 HA A:ASP187 3.3 0.6 1.0 CG A:ASP187 3.5 0.6 1.0 CG A:ASP246 3.5 0.5 1.0 C A:MET186 3.6 0.6 1.0 CA A:CA301 3.6 0.6 1.0 HD22 A:ASN253 3.6 4.0 1.0 HB3 A:MET186 3.7 0.8 1.0 HB2 A:ASP254 3.8 0.7 1.0 OD1 A:ASP254 4.0 1.3 1.0 CA A:ASP187 4.1 0.6 1.0 CB A:ASP254 4.1 0.6 1.0 HD3 A:PRO188 4.1 0.7 1.0 OD1 A:ASP246 4.2 0.7 1.0 CB A:ASP248 4.3 0.7 1.0 N A:ASP187 4.3 0.6 1.0 OD2 A:ASP187 4.3 0.9 1.0 ND2 A:ASN253 4.3 3.5 1.0 HB3 A:ASP246 4.4 0.6 1.0 CB A:ASP187 4.4 0.6 1.0 CB A:MET186 4.5 0.7 1.0 CB A:ASP246 4.6 0.6 1.0 OD1 A:ASN253 4.6 4.2 1.0 HB3 A:ASP254 4.6 0.7 1.0 HB2 A:MET186 4.7 0.8 1.0 HB2 A:ASP248 4.7 0.8 1.0 O A:ASP246 4.7 0.5 1.0 CA A:MET186 4.7 0.7 1.0 HB3 A:ASP248 4.7 0.8 1.0 HA A:ASP248 4.7 0.7 1.0 CG A:ASN253 4.8 3.4 1.0 HD21 A:ASN253 4.9 3.2 1.0 HB3 A:ASP187 5.0 0.6 1.0

Y.Yang, C.Shu, P.Li, T.I.Igumenova. Structural Basis of Protein Kinase C Alpha Regulation By the C-Terminal Tail. Biophys. J. V. 114 1590 2018.
ISSN: ESSN 1542-0086
PubMed: 29642029
DOI: 10.1016/J.BPJ.2017.12.030