Calcium in PDB 6bqv: Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State

The binding sites of Calcium atom in the Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State (pdb code 6bqv). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State, PDB code: 6bqv:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1300 b:70.8 occ:1.00 OE1 A:GLN831 2.3 73.5 1.0 OE2 A:GLU828 2.7 67.7 1.0 OD2 A:ASP868 2.7 54.2 1.0 OD1 A:ASN865 2.7 61.2 1.0 CD A:GLN831 3.3 73.5 1.0 CG A:ASP868 3.7 54.2 1.0 CD A:GLU828 3.7 67.7 1.0 NE2 A:GLN831 3.8 73.5 1.0 CG A:ASN865 3.8 61.2 1.0 OH A:TYR859 3.9 76.0 1.0 OE1 A:GLU828 4.1 67.7 1.0 CB A:ASP868 4.2 54.2 1.0 CA A:ASN865 4.4 61.2 1.0 CB A:ASN865 4.6 61.2 1.0 CG A:GLN831 4.7 73.5 1.0 OD1 A:ASP868 4.7 54.2 1.0 N A:ASN865 4.7 61.2 1.0 CZ A:TYR859 4.7 76.0 1.0 CE1 A:TYR859 4.8 76.0 1.0 ND2 A:ASN865 4.8 61.2 1.0 CB A:GLN831 4.9 73.5 1.0

Calcium binding site 2 out of 4 in the Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1300 b:70.8 occ:1.00 OE1 B:GLN831 2.3 73.5 1.0 OE2 B:GLU828 2.7 67.7 1.0 OD2 B:ASP868 2.7 54.2 1.0 OD1 B:ASN865 2.7 61.2 1.0 CD B:GLN831 3.3 73.5 1.0 CG B:ASP868 3.7 54.2 1.0 CD B:GLU828 3.7 67.7 1.0 NE2 B:GLN831 3.8 73.5 1.0 CG B:ASN865 3.8 61.2 1.0 OH B:TYR859 3.9 76.0 1.0 OE1 B:GLU828 4.1 67.7 1.0 CB B:ASP868 4.2 54.2 1.0 CA B:ASN865 4.4 61.2 1.0 CB B:ASN865 4.6 61.2 1.0 CG B:GLN831 4.7 73.5 1.0 OD1 B:ASP868 4.7 54.2 1.0 N B:ASN865 4.7 61.2 1.0 CZ B:TYR859 4.7 76.0 1.0 CE1 B:TYR859 4.8 76.0 1.0 ND2 B:ASN865 4.8 61.2 1.0 CB B:GLN831 4.9 73.5 1.0

Calcium binding site 3 out of 4 in the Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca1300 b:70.8 occ:1.00 OE1 C:GLN831 2.3 73.5 1.0 OE2 C:GLU828 2.7 67.7 1.0 OD2 C:ASP868 2.7 54.2 1.0 OD1 C:ASN865 2.7 61.2 1.0 CD C:GLN831 3.3 73.5 1.0 CG C:ASP868 3.7 54.2 1.0 CD C:GLU828 3.7 67.7 1.0 NE2 C:GLN831 3.8 73.5 1.0 CG C:ASN865 3.8 61.2 1.0 OH C:TYR859 3.9 76.0 1.0 OE1 C:GLU828 4.1 67.7 1.0 CB C:ASP868 4.2 54.2 1.0 CA C:ASN865 4.4 61.2 1.0 CB C:ASN865 4.6 61.2 1.0 CG C:GLN831 4.7 73.5 1.0 OD1 C:ASP868 4.7 54.2 1.0 N C:ASN865 4.7 61.2 1.0 CZ C:TYR859 4.7 76.0 1.0 CE1 C:TYR859 4.8 76.0 1.0 ND2 C:ASN865 4.8 61.2 1.0 CB C:GLN831 4.9 73.5 1.0

Calcium binding site 4 out of 4 in the Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Human TRPM4 Ion Channel in Lipid Nanodiscs in A Calcium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1300 b:70.8 occ:1.00 OE1 D:GLN831 2.3 73.5 1.0 OE2 D:GLU828 2.7 67.7 1.0 OD2 D:ASP868 2.7 54.2 1.0 OD1 D:ASN865 2.7 61.2 1.0 CD D:GLN831 3.3 73.5 1.0 CG D:ASP868 3.7 54.2 1.0 CD D:GLU828 3.7 67.7 1.0 NE2 D:GLN831 3.8 73.5 1.0 CG D:ASN865 3.8 61.2 1.0 OH D:TYR859 3.9 76.0 1.0 OE1 D:GLU828 4.1 67.7 1.0 CB D:ASP868 4.2 54.2 1.0 CA D:ASN865 4.4 61.2 1.0 CB D:ASN865 4.6 61.2 1.0 CG D:GLN831 4.7 73.5 1.0 OD1 D:ASP868 4.7 54.2 1.0 N D:ASN865 4.7 61.2 1.0 CZ D:TYR859 4.7 76.0 1.0 CE1 D:TYR859 4.8 76.0 1.0 ND2 D:ASN865 4.8 61.2 1.0 CB D:GLN831 4.9 73.5 1.0

H.E.Autzen, A.G.Myasnikov, M.G.Campbell, D.Asarnow, D.Julius, Y.Cheng. Structure of the Human TRPM4 Ion Channel in A Lipid Nanodisc. Science V. 359 228 2018.
ISSN: ESSN 1095-9203
PubMed: 29217581
DOI: 10.1126/SCIENCE.AAR4510