Calcium in PDB 6ckj: N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free

All present enzymatic activity of N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free:
2.7.7.43;

The structure of N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free, PDB code: 6ckj was solved by M.M.Matthews, A.J.Fisher, X.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.78 / 1.75
Space group	C 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	93.783, 155.056, 38.777, 90.00, 90.00, 90.00
R / Rfree (%)	15.7 / 18.7

The binding sites of Calcium atom in the N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free (pdb code 6ckj). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free, PDB code: 6ckj:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca303 b:9.5 occ:0.42 O A:HOH501 2.2 21.2 1.0 O A:ARG156 2.3 13.2 1.0 O A:HOH574 2.4 19.4 0.5 O A:HOH564 2.4 25.4 1.0 C A:ARG156 3.4 14.8 1.0 CA A:ARG156 4.1 13.0 1.0 O A:PRO154 4.3 13.8 1.0 N A:HIS157 4.5 11.8 1.0 O A:HOH596 4.6 33.2 1.0 ND1 A:HIS157 4.7 20.6 1.0 CA A:HIS157 4.7 11.2 1.0 N A:ARG156 4.7 11.1 1.0 O A:HOH510 4.9 33.1 1.0 O A:MET155 4.9 12.7 1.0 O A:HOH578 4.9 12.5 1.0

Calcium binding site 2 out of 2 in the N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of N. Meningitidis Cmp-Sialic Acid Synthetase, Ligand-Free within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca304 b:65.4 occ:0.50 O A:HOH483 2.2 31.6 1.0 O A:HOH416 2.2 33.5 1.0 O A:HOH616 2.3 52.1 1.0 H1 A:ACT302 3.8 43.8 1.0 O A:HOH476 4.2 34.6 1.0 O A:ASP46 4.3 12.7 1.0 O A:HOH594 4.5 31.5 1.0 CH3 A:ACT302 4.7 36.5 1.0 O A:HOH627 4.7 37.8 1.0 O A:PHE45 4.7 15.0 1.0 H3 A:ACT302 4.8 43.8 1.0 O A:HOH551 4.8 44.8 1.0 H2 A:ACT302 4.9 43.8 1.0

M.M.Matthews, H.Yu, Y.Li, X.Chen, A.J.Fisher. Structural Insight Into the Mechanism of Cmp-Sialic Acid Synthetase To Be Published.