Calcium in PDB 6daf: 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
Protein crystallography data
The structure of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex, PDB code: 6daf
was solved by
K.Wang,
F.Van Petegem,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
43.68 /
2.40
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
34.355,
121.309,
125.897,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
20.3 /
24.3
|
Calcium Binding Sites:
The binding sites of Calcium atom in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
(pdb code 6daf). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex, PDB code: 6daf:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 1 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca501
b:87.9
occ:1.00
|
OD2
|
A:ASP20
|
2.3
|
82.1
|
1.0
|
|
OD1
|
A:ASP22
|
2.3
|
0.1
|
1.0
|
|
O
|
A:THR26
|
2.3
|
75.8
|
1.0
|
|
OE1
|
A:GLU31
|
2.4
|
84.0
|
1.0
|
|
OD1
|
A:ASP24
|
2.5
|
80.1
|
1.0
|
|
OE2
|
A:GLU31
|
2.7
|
84.8
|
1.0
|
|
CD
|
A:GLU31
|
2.8
|
85.4
|
1.0
|
|
CG
|
A:ASP22
|
2.9
|
0.8
|
1.0
|
|
OD2
|
A:ASP22
|
2.9
|
0.4
|
1.0
|
|
CG
|
A:ASP24
|
3.2
|
87.6
|
1.0
|
|
CG
|
A:ASP20
|
3.4
|
82.2
|
1.0
|
|
OG1
|
A:THR26
|
3.5
|
80.6
|
1.0
|
|
OD2
|
A:ASP24
|
3.5
|
87.7
|
1.0
|
|
C
|
A:THR26
|
3.5
|
79.7
|
1.0
|
|
CB
|
A:ASP20
|
4.2
|
73.3
|
1.0
|
|
CG
|
A:GLU31
|
4.3
|
89.3
|
1.0
|
|
OD1
|
A:ASP20
|
4.3
|
81.0
|
1.0
|
|
N
|
A:THR26
|
4.3
|
77.7
|
1.0
|
|
CB
|
A:ASP22
|
4.3
|
1.0
|
1.0
|
|
CA
|
A:ASP20
|
4.3
|
72.0
|
1.0
|
|
CA
|
A:THR26
|
4.3
|
78.0
|
1.0
|
|
CB
|
A:ASP24
|
4.4
|
89.9
|
1.0
|
|
N
|
A:ASP22
|
4.5
|
0.9
|
1.0
|
|
N
|
A:ILE27
|
4.5
|
79.8
|
1.0
|
|
N
|
A:ASP24
|
4.5
|
92.9
|
1.0
|
|
CB
|
A:THR26
|
4.5
|
80.4
|
1.0
|
|
C
|
A:ASP20
|
4.6
|
78.4
|
1.0
|
|
CA
|
A:ILE27
|
4.6
|
78.3
|
1.0
|
|
N
|
A:GLY23
|
4.8
|
97.6
|
1.0
|
|
N
|
A:THR28
|
4.8
|
79.7
|
1.0
|
|
N
|
A:LYS21
|
4.8
|
83.7
|
1.0
|
|
CA
|
A:ASP22
|
4.8
|
0.7
|
1.0
|
|
CG2
|
A:THR28
|
4.9
|
87.6
|
1.0
|
|
CA
|
A:ASP24
|
4.9
|
88.9
|
1.0
|
|
C
|
A:ASP22
|
5.0
|
0.3
|
1.0
|
|
Calcium binding site 2 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 2 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca502
b:87.6
occ:1.00
|
OD1
|
A:ASN60
|
2.3
|
96.9
|
1.0
|
|
O
|
A:THR62
|
2.4
|
98.8
|
1.0
|
|
OE2
|
A:GLU67
|
2.6
|
77.8
|
1.0
|
|
OD1
|
A:ASP58
|
2.7
|
0.9
|
1.0
|
|
OE1
|
A:GLU67
|
2.7
|
74.6
|
1.0
|
|
OD1
|
A:ASP56
|
2.8
|
94.9
|
1.0
|
|
CD
|
A:GLU67
|
3.0
|
75.7
|
1.0
|
|
CG
|
A:ASN60
|
3.1
|
96.6
|
1.0
|
|
C
|
A:THR62
|
3.4
|
94.6
|
1.0
|
|
ND2
|
A:ASN60
|
3.4
|
86.8
|
1.0
|
|
CG
|
A:ASP58
|
3.5
|
0.4
|
1.0
|
|
OD2
|
A:ASP58
|
3.6
|
0.6
|
1.0
|
|
CG
|
A:ASP56
|
3.7
|
97.0
|
1.0
|
|
OD2
|
A:ASP64
|
4.0
|
83.4
|
1.0
|
|
N
|
A:ASP64
|
4.2
|
74.3
|
1.0
|
|
N
|
A:ILE63
|
4.2
|
84.6
|
1.0
|
|
N
|
A:ASN60
|
4.3
|
0.4
|
1.0
|
|
CA
|
A:ILE63
|
4.3
|
74.3
|
1.0
|
|
CA
|
A:THR62
|
4.3
|
97.8
|
1.0
|
|
N
|
A:THR62
|
4.3
|
0.8
|
1.0
|
|
CB
|
A:ASN60
|
4.4
|
0.5
|
1.0
|
|
CG
|
A:ASP64
|
4.4
|
75.7
|
1.0
|
|
OD2
|
A:ASP56
|
4.5
|
0.8
|
1.0
|
|
CB
|
A:ASP56
|
4.5
|
94.1
|
1.0
|
|
CG
|
A:GLU67
|
4.5
|
67.7
|
1.0
|
|
CB
|
A:THR62
|
4.6
|
95.6
|
1.0
|
|
C
|
A:ILE63
|
4.6
|
74.4
|
1.0
|
|
CA
|
A:ASP56
|
4.7
|
91.1
|
1.0
|
|
CA
|
A:ASN60
|
4.8
|
0.8
|
1.0
|
|
CG2
|
A:THR62
|
4.8
|
96.4
|
1.0
|
|
N
|
A:GLY59
|
4.8
|
92.8
|
1.0
|
|
CB
|
A:ASP58
|
4.8
|
91.2
|
1.0
|
|
N
|
A:ASP58
|
4.9
|
97.2
|
1.0
|
|
CB
|
A:ASP64
|
4.9
|
69.0
|
1.0
|
|
OD1
|
A:ASP64
|
5.0
|
74.2
|
1.0
|
|
C
|
A:ASN60
|
5.0
|
0.9
|
1.0
|
|
Calcium binding site 3 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 3 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca503
b:50.2
occ:1.00
|
OD1
|
A:ASN97
|
2.3
|
50.1
|
1.0
|
|
O
|
A:TYR99
|
2.3
|
55.4
|
1.0
|
|
OE2
|
A:GLU104
|
2.3
|
50.5
|
1.0
|
|
OD1
|
A:ASP93
|
2.3
|
63.4
|
1.0
|
|
O
|
A:HOH608
|
2.4
|
66.7
|
1.0
|
|
OD1
|
A:ASP95
|
2.5
|
64.5
|
1.0
|
|
OE1
|
A:GLU104
|
2.6
|
49.5
|
1.0
|
|
CD
|
A:GLU104
|
2.8
|
53.2
|
1.0
|
|
CG
|
A:ASN97
|
3.3
|
52.6
|
1.0
|
|
CG
|
A:ASP93
|
3.4
|
60.9
|
1.0
|
|
CG
|
A:ASP95
|
3.4
|
64.0
|
1.0
|
|
C
|
A:TYR99
|
3.5
|
49.3
|
1.0
|
|
OD2
|
A:ASP95
|
3.9
|
65.6
|
1.0
|
|
ND2
|
A:ASN97
|
4.0
|
49.5
|
1.0
|
|
OD2
|
A:ASP93
|
4.1
|
64.6
|
1.0
|
|
CA
|
A:ASP93
|
4.1
|
58.3
|
1.0
|
|
N
|
A:TYR99
|
4.2
|
44.9
|
1.0
|
|
N
|
A:ASN97
|
4.2
|
52.0
|
1.0
|
|
CB
|
A:ASP93
|
4.3
|
56.6
|
1.0
|
|
N
|
A:ASP95
|
4.3
|
58.6
|
1.0
|
|
CA
|
A:TYR99
|
4.3
|
51.1
|
1.0
|
|
CG
|
A:GLU104
|
4.3
|
42.3
|
1.0
|
|
CB
|
A:ASN97
|
4.4
|
50.2
|
1.0
|
|
C
|
A:ASP93
|
4.4
|
56.2
|
1.0
|
|
N
|
A:ILE100
|
4.5
|
51.5
|
1.0
|
|
N
|
A:LYS94
|
4.5
|
60.2
|
1.0
|
|
CB
|
A:TYR99
|
4.6
|
50.2
|
1.0
|
|
CB
|
A:ASP95
|
4.6
|
58.8
|
1.0
|
|
CA
|
A:ILE100
|
4.6
|
50.1
|
1.0
|
|
N
|
A:GLY96
|
4.7
|
53.5
|
1.0
|
|
CA
|
A:ASN97
|
4.7
|
47.2
|
1.0
|
|
CA
|
A:ASP95
|
4.8
|
55.7
|
1.0
|
|
N
|
A:SER101
|
4.8
|
51.8
|
1.0
|
|
C
|
A:ASP95
|
4.9
|
52.3
|
1.0
|
|
O
|
A:ASP93
|
4.9
|
54.1
|
1.0
|
|
N
|
A:GLY98
|
4.9
|
51.2
|
1.0
|
|
Calcium binding site 4 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 4 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca504
b:58.1
occ:1.00
|
OD1
|
A:ASP131
|
2.3
|
76.9
|
1.0
|
|
O
|
A:GLN135
|
2.3
|
53.1
|
1.0
|
|
OD1
|
A:ASP129
|
2.4
|
57.0
|
1.0
|
|
OD1
|
A:ASP133
|
2.4
|
62.4
|
1.0
|
|
OE1
|
A:GLU140
|
2.5
|
71.7
|
1.0
|
|
O
|
A:HOH601
|
2.5
|
69.2
|
1.0
|
|
OE2
|
A:GLU140
|
2.7
|
75.7
|
1.0
|
|
CD
|
A:GLU140
|
2.9
|
73.1
|
1.0
|
|
CG
|
A:ASP133
|
3.2
|
59.5
|
1.0
|
|
CG
|
A:ASP131
|
3.3
|
77.4
|
1.0
|
|
C
|
A:GLN135
|
3.4
|
49.5
|
1.0
|
|
OD2
|
A:ASP133
|
3.5
|
64.0
|
1.0
|
|
CG
|
A:ASP129
|
3.5
|
60.2
|
1.0
|
|
OD2
|
A:ASP131
|
3.7
|
80.7
|
1.0
|
|
N
|
A:VAL136
|
4.2
|
48.5
|
1.0
|
|
N
|
A:GLN135
|
4.2
|
51.9
|
1.0
|
|
CA
|
A:VAL136
|
4.2
|
48.7
|
1.0
|
|
CA
|
A:ASP129
|
4.3
|
68.1
|
1.0
|
|
OD2
|
A:ASP129
|
4.3
|
61.5
|
1.0
|
|
CB
|
A:ASP129
|
4.4
|
60.9
|
1.0
|
|
N
|
A:ASP133
|
4.4
|
60.9
|
1.0
|
|
N
|
A:ASP131
|
4.4
|
69.5
|
1.0
|
|
N
|
A:ASN137
|
4.4
|
57.7
|
1.0
|
|
CA
|
A:GLN135
|
4.4
|
44.8
|
1.0
|
|
CG
|
A:GLU140
|
4.4
|
74.7
|
1.0
|
|
N
|
A:ILE130
|
4.5
|
75.0
|
1.0
|
|
CB
|
A:ASP133
|
4.5
|
50.2
|
1.0
|
|
CB
|
A:ASP131
|
4.6
|
71.4
|
1.0
|
|
N
|
A:GLY132
|
4.7
|
75.0
|
1.0
|
|
CG
|
A:GLN135
|
4.8
|
50.3
|
1.0
|
|
C
|
A:VAL136
|
4.8
|
55.7
|
1.0
|
|
C
|
A:ASP129
|
4.8
|
73.8
|
1.0
|
|
CA
|
A:ASP133
|
4.9
|
54.5
|
1.0
|
|
CA
|
A:ASP131
|
4.9
|
74.9
|
1.0
|
|
N
|
A:GLY134
|
4.9
|
62.2
|
1.0
|
|
Calcium binding site 5 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 5 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca501
b:84.6
occ:1.00
|
O
|
B:THR26
|
2.1
|
83.7
|
1.0
|
|
OE1
|
B:GLU31
|
2.2
|
83.7
|
1.0
|
|
OD1
|
B:ASP22
|
2.2
|
87.7
|
1.0
|
|
OD1
|
B:ASP24
|
2.4
|
92.1
|
1.0
|
|
OD1
|
B:ASP20
|
2.5
|
75.7
|
1.0
|
|
CD
|
B:GLU31
|
2.9
|
88.5
|
1.0
|
|
OE2
|
B:GLU31
|
3.0
|
87.2
|
1.0
|
|
CG
|
B:ASP22
|
3.1
|
89.9
|
1.0
|
|
C
|
B:THR26
|
3.2
|
85.5
|
1.0
|
|
OD2
|
B:ASP22
|
3.3
|
94.1
|
1.0
|
|
CG
|
B:ASP24
|
3.3
|
92.3
|
1.0
|
|
CG
|
B:ASP20
|
3.5
|
81.7
|
1.0
|
|
CG2
|
B:THR26
|
3.7
|
97.7
|
1.0
|
|
OD2
|
B:ASP24
|
3.7
|
92.8
|
1.0
|
|
N
|
B:THR26
|
4.0
|
83.7
|
1.0
|
|
CA
|
B:THR26
|
4.1
|
86.5
|
1.0
|
|
CA
|
B:ASP20
|
4.1
|
76.4
|
1.0
|
|
CB
|
B:ASP20
|
4.1
|
75.2
|
1.0
|
|
N
|
B:ILE27
|
4.2
|
77.5
|
1.0
|
|
CG
|
B:GLU31
|
4.3
|
94.5
|
1.0
|
|
CA
|
B:ILE27
|
4.3
|
69.9
|
1.0
|
|
N
|
B:ASP24
|
4.4
|
92.9
|
1.0
|
|
CB
|
B:ASP24
|
4.5
|
94.0
|
1.0
|
|
C
|
B:ASP20
|
4.5
|
80.5
|
1.0
|
|
OD2
|
B:ASP20
|
4.5
|
77.0
|
1.0
|
|
N
|
B:ASP22
|
4.5
|
93.3
|
1.0
|
|
CB
|
B:ASP22
|
4.5
|
96.1
|
1.0
|
|
CB
|
B:THR26
|
4.5
|
98.7
|
1.0
|
|
N
|
B:THR28
|
4.6
|
77.5
|
1.0
|
|
N
|
B:LYS21
|
4.7
|
81.0
|
1.0
|
|
N
|
B:GLY23
|
4.7
|
96.0
|
1.0
|
|
CA
|
B:ASP24
|
4.8
|
90.6
|
1.0
|
|
N
|
B:GLY25
|
4.9
|
83.1
|
1.0
|
|
CA
|
B:ASP22
|
4.9
|
97.3
|
1.0
|
|
C
|
B:ASP24
|
4.9
|
85.7
|
1.0
|
|
C
|
B:ILE27
|
4.9
|
74.1
|
1.0
|
|
C
|
B:ASP22
|
5.0
|
98.6
|
1.0
|
|
Calcium binding site 6 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 6 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca502
b:87.0
occ:1.00
|
OD1
|
B:ASN60
|
2.2
|
95.8
|
1.0
|
|
O
|
B:THR62
|
2.4
|
80.5
|
1.0
|
|
OE2
|
B:GLU67
|
2.5
|
73.3
|
1.0
|
|
OE1
|
B:GLU67
|
2.6
|
80.5
|
1.0
|
|
OD1
|
B:ASP56
|
2.9
|
95.1
|
1.0
|
|
CD
|
B:GLU67
|
2.9
|
76.3
|
1.0
|
|
OD1
|
B:ASP58
|
2.9
|
0.1
|
1.0
|
|
CG
|
B:ASN60
|
3.2
|
0.9
|
1.0
|
|
C
|
B:THR62
|
3.3
|
79.3
|
1.0
|
|
ND2
|
B:ASN60
|
3.5
|
100.0
|
1.0
|
|
CG
|
B:ASP56
|
3.8
|
97.0
|
1.0
|
|
OG1
|
B:THR62
|
3.8
|
89.5
|
1.0
|
|
CG
|
B:ASP58
|
3.9
|
0.6
|
1.0
|
|
OD2
|
B:ASP58
|
4.0
|
0.6
|
1.0
|
|
N
|
B:ILE63
|
4.1
|
75.4
|
1.0
|
|
N
|
B:THR62
|
4.2
|
95.7
|
1.0
|
|
CA
|
B:ILE63
|
4.2
|
70.0
|
1.0
|
|
N
|
B:ASP64
|
4.2
|
72.0
|
1.0
|
|
CA
|
B:THR62
|
4.2
|
84.6
|
1.0
|
|
OD2
|
B:ASP64
|
4.3
|
81.4
|
1.0
|
|
CG
|
B:GLU67
|
4.4
|
65.3
|
1.0
|
|
OD2
|
B:ASP56
|
4.5
|
98.9
|
1.0
|
|
C
|
B:ILE63
|
4.5
|
73.1
|
1.0
|
|
CB
|
B:ASN60
|
4.5
|
0.6
|
1.0
|
|
CB
|
B:ASP56
|
4.6
|
94.4
|
1.0
|
|
CG
|
B:ASP64
|
4.6
|
74.2
|
1.0
|
|
CB
|
B:THR62
|
4.6
|
87.9
|
1.0
|
|
CA
|
B:ASP56
|
4.6
|
92.2
|
1.0
|
|
N
|
B:ASN60
|
4.6
|
0.4
|
1.0
|
|
OD1
|
B:ASP64
|
5.0
|
73.3
|
1.0
|
|
CA
|
B:ASN60
|
5.0
|
0.1
|
1.0
|
|
N
|
B:ALA57
|
5.0
|
96.3
|
1.0
|
|
Calcium binding site 7 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 7 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca503
b:49.3
occ:1.00
|
O
|
B:TYR99
|
2.2
|
53.6
|
1.0
|
|
O
|
B:HOH608
|
2.4
|
61.4
|
1.0
|
|
OD1
|
B:ASP93
|
2.4
|
47.5
|
1.0
|
|
OD1
|
B:ASP95
|
2.4
|
71.1
|
1.0
|
|
OD1
|
B:ASN97
|
2.4
|
44.0
|
1.0
|
|
OE2
|
B:GLU104
|
2.5
|
53.9
|
1.0
|
|
OE1
|
B:GLU104
|
2.6
|
50.7
|
1.0
|
|
CD
|
B:GLU104
|
2.9
|
49.5
|
1.0
|
|
CG
|
B:ASP95
|
3.3
|
69.1
|
1.0
|
|
CG
|
B:ASN97
|
3.4
|
46.3
|
1.0
|
|
C
|
B:TYR99
|
3.5
|
48.2
|
1.0
|
|
CG
|
B:ASP93
|
3.5
|
56.4
|
1.0
|
|
OD2
|
B:ASP95
|
3.6
|
76.8
|
1.0
|
|
ND2
|
B:ASN97
|
4.1
|
52.6
|
1.0
|
|
N
|
B:TYR99
|
4.2
|
49.0
|
1.0
|
|
N
|
B:ASN97
|
4.2
|
55.9
|
1.0
|
|
CA
|
B:ASP93
|
4.2
|
51.1
|
1.0
|
|
N
|
B:ASP95
|
4.3
|
59.8
|
1.0
|
|
CA
|
B:TYR99
|
4.3
|
47.7
|
1.0
|
|
OD2
|
B:ASP93
|
4.4
|
56.9
|
1.0
|
|
CB
|
B:ASP93
|
4.4
|
47.0
|
1.0
|
|
N
|
B:ILE100
|
4.4
|
48.2
|
1.0
|
|
C
|
B:ASP93
|
4.5
|
56.7
|
1.0
|
|
CG
|
B:GLU104
|
4.5
|
45.5
|
1.0
|
|
CA
|
B:ILE100
|
4.5
|
48.0
|
1.0
|
|
CB
|
B:ASN97
|
4.5
|
49.3
|
1.0
|
|
N
|
B:SER101
|
4.5
|
52.7
|
1.0
|
|
N
|
B:GLY96
|
4.5
|
55.7
|
1.0
|
|
CB
|
B:ASP95
|
4.6
|
66.6
|
1.0
|
|
N
|
B:LYS94
|
4.6
|
50.2
|
1.0
|
|
CA
|
B:ASN97
|
4.8
|
64.2
|
1.0
|
|
CB
|
B:TYR99
|
4.8
|
48.8
|
1.0
|
|
CA
|
B:ASP95
|
4.8
|
64.5
|
1.0
|
|
C
|
B:ASP95
|
4.8
|
55.4
|
1.0
|
|
N
|
B:GLY98
|
4.8
|
55.4
|
1.0
|
|
C
|
B:ILE100
|
5.0
|
53.5
|
1.0
|
|
C
|
B:ASN97
|
5.0
|
60.7
|
1.0
|
|
O
|
B:ASP93
|
5.0
|
54.7
|
1.0
|
|
Calcium binding site 8 out
of 8 in 6daf
Go back to
Calcium Binding Sites List in 6daf
Calcium binding site 8 out
of 8 in the 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of 2.4 Angstrom Crystal Structure of the F141L Ca/Cam:CAV1.2 Iq Domain Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca504
b:61.7
occ:1.00
|
O
|
B:GLN135
|
2.3
|
59.5
|
1.0
|
|
OE1
|
B:GLU140
|
2.3
|
54.9
|
1.0
|
|
OD1
|
B:ASP133
|
2.4
|
60.8
|
1.0
|
|
OD1
|
B:ASP129
|
2.4
|
72.3
|
1.0
|
|
OE2
|
B:GLU140
|
2.4
|
48.6
|
1.0
|
|
OD1
|
B:ASP131
|
2.5
|
72.3
|
1.0
|
|
O
|
B:HOH606
|
2.6
|
57.1
|
1.0
|
|
CD
|
B:GLU140
|
2.7
|
47.9
|
1.0
|
|
CG
|
B:ASP133
|
3.3
|
63.2
|
1.0
|
|
CG
|
B:ASP131
|
3.3
|
71.3
|
1.0
|
|
CG
|
B:ASP129
|
3.5
|
68.3
|
1.0
|
|
C
|
B:GLN135
|
3.5
|
53.3
|
1.0
|
|
OD2
|
B:ASP131
|
3.5
|
75.7
|
1.0
|
|
OD2
|
B:ASP133
|
3.6
|
65.8
|
1.0
|
|
CA
|
B:ASP129
|
4.1
|
62.6
|
1.0
|
|
CB
|
B:ASP129
|
4.2
|
58.8
|
1.0
|
|
N
|
B:ASP133
|
4.2
|
72.9
|
1.0
|
|
N
|
B:GLN135
|
4.3
|
64.7
|
1.0
|
|
CG
|
B:GLU140
|
4.3
|
52.7
|
1.0
|
|
N
|
B:ASN137
|
4.3
|
45.7
|
1.0
|
|
OD2
|
B:ASP129
|
4.3
|
73.3
|
1.0
|
|
CA
|
B:VAL136
|
4.3
|
47.0
|
1.0
|
|
N
|
B:VAL136
|
4.3
|
50.5
|
1.0
|
|
N
|
B:ASP131
|
4.4
|
69.5
|
1.0
|
|
CB
|
B:ASP133
|
4.4
|
64.4
|
1.0
|
|
C
|
B:ASP129
|
4.5
|
69.9
|
1.0
|
|
N
|
B:GLY132
|
4.5
|
72.3
|
1.0
|
|
CA
|
B:GLN135
|
4.5
|
55.1
|
1.0
|
|
N
|
B:ILE130
|
4.6
|
68.3
|
1.0
|
|
CB
|
B:ASP131
|
4.6
|
66.0
|
1.0
|
|
C
|
B:VAL136
|
4.8
|
47.9
|
1.0
|
|
CA
|
B:ASP133
|
4.8
|
68.0
|
1.0
|
|
CA
|
B:ASP131
|
4.8
|
71.7
|
1.0
|
|
N
|
B:GLY134
|
4.9
|
67.8
|
1.0
|
|
CG
|
B:ASN137
|
4.9
|
55.2
|
1.0
|
|
C
|
B:ASP131
|
4.9
|
73.8
|
1.0
|
|
OD1
|
B:ASN137
|
5.0
|
61.2
|
1.0
|
|
O
|
B:HOH605
|
5.0
|
61.9
|
1.0
|
|
Reference:
K.Wang,
C.Holt,
J.Lu,
M.Brohus,
K.T.Larsen,
M.T.Overgaard,
R.Wimmer,
F.Van Petegem.
Arrhythmia Mutations in Calmodulin Cause Conformational Changes That Affect Interactions with the Cardiac Voltage-Gated Calcium Channel. Proc. Natl. Acad. Sci. V. 115 10556 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30348784
DOI: 10.1073/PNAS.1808733115
Page generated: Sat Dec 12 06:02:48 2020
|
