Calcium in PDB 6drj: Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State

The binding sites of Calcium atom in the Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State (pdb code 6drj). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State, PDB code: 6drj:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2002 b:0.1 occ:1.00 OE1 A:GLN860 2.1 0.8 1.0 OE2 A:GLU857 2.6 0.5 1.0 OD1 A:ASN883 2.7 0.7 1.0 OE1 A:GLU857 2.8 0.5 1.0 CD A:GLN860 2.9 0.8 1.0 OE2 A:GLU1088 3.0 0.2 1.0 CD A:GLU857 3.0 0.5 1.0 NE2 A:GLN860 3.1 0.8 1.0 OD2 A:ASP886 3.7 30.0 1.0 CG A:ASN883 3.9 0.7 1.0 CD A:GLU1088 4.2 0.2 1.0 CG A:GLN860 4.2 0.8 1.0 OH A:TYR877 4.3 0.2 1.0 NH2 A:ARG1092 4.4 0.9 1.0 CG A:GLU857 4.5 0.5 1.0 CB A:GLN860 4.5 0.8 1.0 ND2 A:ASN883 4.6 0.7 1.0 CG A:ASP886 4.8 30.0 1.0 NH1 A:ARG925 4.9 94.4 1.0

Calcium binding site 2 out of 4 in the Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca2002 b:0.1 occ:1.00 OE1 B:GLN860 2.1 0.8 1.0 OE2 B:GLU857 2.6 0.5 1.0 OD1 B:ASN883 2.7 0.7 1.0 OE1 B:GLU857 2.8 0.5 1.0 CD B:GLN860 2.9 0.8 1.0 OE2 B:GLU1088 3.0 0.2 1.0 CD B:GLU857 3.0 0.5 1.0 NE2 B:GLN860 3.1 0.8 1.0 OD2 B:ASP886 3.7 30.0 1.0 CG B:ASN883 3.9 0.7 1.0 CD B:GLU1088 4.2 0.2 1.0 CG B:GLN860 4.2 0.8 1.0 OH B:TYR877 4.3 0.2 1.0 NH2 B:ARG1092 4.4 0.9 1.0 CG B:GLU857 4.5 0.5 1.0 CB B:GLN860 4.5 0.8 1.0 ND2 B:ASN883 4.6 0.7 1.0 CG B:ASP886 4.8 30.0 1.0 NH1 B:ARG925 4.9 94.4 1.0

Calcium binding site 3 out of 4 in the Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca2002 b:0.1 occ:1.00 OE1 C:GLN860 2.1 0.8 1.0 OE2 C:GLU857 2.6 0.5 1.0 OD1 C:ASN883 2.7 0.7 1.0 OE1 C:GLU857 2.8 0.5 1.0 CD C:GLN860 2.9 0.8 1.0 OE2 C:GLU1088 3.0 0.2 1.0 CD C:GLU857 3.0 0.5 1.0 NE2 C:GLN860 3.1 0.8 1.0 OD2 C:ASP886 3.7 30.0 1.0 CG C:ASN883 3.9 0.7 1.0 CD C:GLU1088 4.2 0.2 1.0 CG C:GLN860 4.2 0.8 1.0 OH C:TYR877 4.3 0.2 1.0 NH2 C:ARG1092 4.4 0.9 1.0 CG C:GLU857 4.5 0.5 1.0 CB C:GLN860 4.5 0.8 1.0 ND2 C:ASN883 4.6 0.7 1.0 CG C:ASP886 4.8 30.0 1.0 NH1 C:ARG925 4.9 94.4 1.0

Calcium binding site 4 out of 4 in the Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of TRPM2 Ion Channel Receptor By Single Particle Electron Cryo-Microscopy, Adpr/CA2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca2002 b:0.1 occ:1.00 OE1 D:GLN860 2.1 0.8 1.0 OE2 D:GLU857 2.6 0.5 1.0 OD1 D:ASN883 2.7 0.7 1.0 OE1 D:GLU857 2.8 0.5 1.0 CD D:GLN860 2.9 0.8 1.0 OE2 D:GLU1088 3.0 0.2 1.0 CD D:GLU857 3.0 0.5 1.0 NE2 D:GLN860 3.1 0.8 1.0 OD2 D:ASP886 3.7 30.0 1.0 CG D:ASN883 3.9 0.7 1.0 CD D:GLU1088 4.2 0.2 1.0 CG D:GLN860 4.2 0.8 1.0 OH D:TYR877 4.3 0.2 1.0 NH2 D:ARG1092 4.4 0.9 1.0 CG D:GLU857 4.5 0.5 1.0 CB D:GLN860 4.5 0.8 1.0 ND2 D:ASN883 4.6 0.7 1.0 CG D:ASP886 4.8 30.0 1.0 NH1 D:ARG925 4.9 94.4 1.0

Y.Huang, P.A.Winkler, W.Sun, W.Lu, J.Du. Architecture of the TRPM2 Channel and Its Activation Mechanism By Adp-Ribose and Calcium. Nature V. 562 145 2018.
ISSN: ISSN 0028-0836
PubMed: 30250252
DOI: 10.1038/S41586-018-0558-4