Calcium in PDB 6e1h: Structure of 2:1 Human PTCH1-Shh-N Complex

The structure of Structure of 2:1 Human PTCH1-Shh-N Complex also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Calcium atom in the Structure of 2:1 Human PTCH1-Shh-N Complex (pdb code 6e1h). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of 2:1 Human PTCH1-Shh-N Complex, PDB code: 6e1h:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of 2:1 Human PTCH1-Shh-N Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of 2:1 Human PTCH1-Shh-N Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca202 b:76.4 occ:1.00 O C:THR125 2.0 71.4 1.0 CA C:CA203 2.3 81.3 1.0 OD2 C:ASP95 2.8 80.9 1.0 C C:THR125 3.1 71.4 1.0 OD1 C:ASP95 3.2 80.9 1.0 CG C:GLU89 3.3 83.8 1.0 CG C:ASP95 3.3 80.9 1.0 CG C:GLU126 3.4 81.0 1.0 OE2 C:GLU89 3.4 83.8 1.0 CD C:GLU89 3.4 83.8 1.0 CA C:GLU126 3.8 81.0 1.0 OE1 C:GLU90 3.8 84.4 1.0 N C:GLU126 3.9 81.0 1.0 N C:GLU89 4.1 83.8 1.0 CB C:GLU126 4.1 81.0 1.0 CB C:GLU89 4.2 83.8 1.0 CA C:THR125 4.2 71.4 1.0 OE1 C:GLU89 4.3 83.8 1.0 N C:ASP88 4.4 79.7 1.0 OE2 C:GLU90 4.5 84.4 1.0 CD C:GLU126 4.5 81.0 1.0 CB C:LYS87 4.6 75.0 1.0 CD C:GLU90 4.6 84.4 1.0 OE2 C:GLU126 4.6 81.0 1.0 CD C:LYS87 4.7 75.0 1.0 CB C:ASP95 4.7 80.9 1.0 OD1 C:ASP129 4.7 89.0 1.0 CA C:GLU89 4.7 83.8 1.0 CB C:THR125 4.8 71.4 1.0 CG C:LYS87 4.9 75.0 1.0 CA C:ASP88 4.9 79.7 1.0

Calcium binding site 2 out of 2 in the Structure of 2:1 Human PTCH1-Shh-N Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of 2:1 Human PTCH1-Shh-N Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca203 b:81.3 occ:1.00 CA C:CA202 2.3 76.4 1.0 OD1 C:ASP95 2.4 80.9 1.0 OD1 C:ASP129 2.6 89.0 1.0 OE1 C:GLU90 2.6 84.4 1.0 OE2 C:GLU90 2.8 84.4 1.0 CD C:GLU90 3.1 84.4 1.0 CG C:ASP95 3.2 80.9 1.0 OD2 C:ASP95 3.4 80.9 1.0 CG C:ASP129 3.5 89.0 1.0 OE2 C:GLU89 3.6 83.8 1.0 CG C:GLU126 3.6 81.0 1.0 OD2 C:ASP129 3.6 89.0 1.0 O C:THR125 3.6 71.4 1.0 CG C:GLU89 3.9 83.8 1.0 CA C:GLU126 4.0 81.0 1.0 CB C:GLU126 4.1 81.0 1.0 CD C:GLU89 4.2 83.8 1.0 CD C:GLU126 4.5 81.0 1.0 CG C:GLU90 4.6 84.4 1.0 C C:THR125 4.6 71.4 1.0 CB C:ASP95 4.7 80.9 1.0 OE2 C:GLU126 4.7 81.0 1.0 N C:GLU126 4.8 81.0 1.0 CB C:ASP129 4.9 89.0 1.0 C C:GLU126 5.0 81.0 1.0 N C:GLY127 5.0 82.0 1.0

X.Qi, P.Schmiege, E.Coutavas, X.Li. Two Patched Molecules Engage Distinct Sites on Hedgehog Yielding A Signaling-Competent Complex. Science V. 362 2018.
ISSN: ESSN 1095-9203
PubMed: 30139912
DOI: 10.1126/SCIENCE.AAS8843