Calcium in PDB 6e1k: Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab

The binding sites of Calcium atom in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab (pdb code 6e1k). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 7 binding sites of Calcium where determined in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab, PDB code: 6e1k:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7;

Calcium binding site 1 out of 7 in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca801 b:96.5 occ:1.00 CA B:CA801 3.8 96.6 1.0 OD1 B:ASN631 4.1 44.1 1.0 OD1 A:ASN631 4.2 43.6 1.0 N A:ASN631 4.2 43.6 1.0 N B:ASN631 4.2 44.1 1.0 O B:SER265 4.4 38.2 1.0 O A:SER265 4.4 36.6 1.0 CB A:SER265 4.6 36.6 1.0 CA A:SER265 4.6 36.6 1.0 CB B:SER265 4.6 38.2 1.0 CA B:SER265 4.6 38.2 1.0 O B:MET629 4.7 43.7 1.0 CG B:ASN631 4.8 44.1 1.0 CG A:ASN631 4.8 43.6 1.0 O A:MET629 4.8 43.8 1.0 CA A:ASN631 4.8 43.6 1.0 CA B:ASN631 4.8 44.1 1.0 C A:SER265 5.0 36.6 1.0 C B:SER265 5.0 38.2 1.0

Calcium binding site 2 out of 7 in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca802 b:69.2 occ:1.00 OD1 B:ASP606 3.4 54.0 1.0 OD1 A:ASP606 3.5 53.6 1.0 CG B:ASP606 4.5 54.0 1.0 CG A:ASP606 4.6 53.6 1.0 OD2 B:ASP606 4.8 54.0 1.0 OD2 A:ASP606 5.0 53.6 1.0

Calcium binding site 3 out of 7 in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca803 b:0.4 occ:1.00 OE2 A:GLU374 2.8 0.9 1.0 CG A:ASP376 2.9 0.6 1.0 CD A:GLU374 3.1 0.9 1.0 OD2 A:ASP376 3.1 0.6 1.0 OE1 A:GLU374 3.2 0.9 1.0 OD1 A:ASP376 3.2 0.6 1.0 CB A:ASP376 3.3 0.6 1.0 CA A:ASP376 4.0 0.6 1.0 CG A:GLU374 4.1 0.9 1.0 N A:ASP376 4.6 0.6 1.0 CB A:GLU374 4.9 0.9 1.0

Calcium binding site 4 out of 7 in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca804 b:0.0 occ:1.00 OD1 A:ASP335 2.5 0.6 1.0 OD1 A:ASP337 2.6 0.4 1.0 OE2 A:GLU341 2.6 0.2 1.0 ND2 A:ASN339 2.6 0.8 1.0 OD1 A:ASN339 2.7 0.8 1.0 CG A:ASN339 2.9 0.8 1.0 CG A:ASP335 3.2 0.6 1.0 OD2 A:ASP335 3.3 0.6 1.0 CD A:GLU341 3.3 0.2 1.0 CG A:ASP337 3.4 0.4 1.0 CG A:GLU341 3.4 0.2 1.0 OD2 A:ASP337 3.6 0.4 1.0 CB A:ASN339 4.2 0.8 1.0 OE1 A:GLU341 4.3 0.2 1.0 N A:ASP337 4.7 0.4 1.0 CB A:ASP335 4.7 0.6 1.0 N A:ASN339 4.7 0.8 1.0 OG A:SER336 4.8 0.9 1.0 CB A:GLU341 4.8 0.2 1.0 CB A:ASP337 4.8 0.4 1.0 N A:SER336 4.9 0.9 1.0

Calcium binding site 5 out of 7 in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca801 b:96.6 occ:1.00 CA A:CA801 3.8 96.5 1.0 O B:MET629 3.9 43.7 1.0 O A:MET629 4.0 43.8 1.0 OG1 A:THR264 4.1 38.7 1.0 OG1 B:THR264 4.2 39.0 1.0 C B:MET629 4.9 43.7 1.0 CB A:SER265 4.9 36.6 1.0 CB B:SER265 4.9 38.2 1.0 CA A:SER265 5.0 36.6 1.0 CA B:SER265 5.0 38.2 1.0

Calcium binding site 6 out of 7 in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca802 b:1.0 occ:1.00 OE2 B:GLU374 2.6 0.7 1.0 OE1 B:GLU374 2.6 0.7 1.0 CD B:GLU374 2.9 0.7 1.0 CD2 B:PHE368 4.2 0.0 1.0 CB B:PHE368 4.3 0.0 1.0 CG B:GLU374 4.4 0.7 1.0 CG B:PHE368 4.7 0.0 1.0

Calcium binding site 7 out of 7 in the Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Structure of ATTPC1(Dde) Reconstituted in Saposin A with CAT06 Fab within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca803 b:0.5 occ:1.00 OD2 B:ASP337 2.3 0.1 1.0 O B:GLU341 2.5 0.5 1.0 OD1 B:ASN339 2.5 0.1 1.0 OD1 B:ASP335 2.6 0.9 1.0 OD1 B:ASP337 2.6 0.1 1.0 ND2 B:ASN339 2.6 0.1 1.0 CG B:ASP337 2.8 0.1 1.0 CG B:ASN339 2.8 0.1 1.0 CG B:ASP335 3.5 0.9 1.0 C B:GLU341 3.8 0.5 1.0 CB B:ASP335 4.1 0.9 1.0 CB B:ASN339 4.2 0.1 1.0 CB B:ASP337 4.3 0.1 1.0 OD2 B:ASP335 4.3 0.9 1.0 CA B:ASP335 4.3 0.9 1.0 CA B:ILE342 4.4 0.1 1.0 N B:ILE342 4.5 0.1 1.0 N B:GLU341 4.6 0.5 1.0 N B:ASN339 4.6 0.1 1.0 CA B:GLU341 4.8 0.5 1.0 CG2 B:ILE342 4.9 0.1 1.0

A.F.Kintzer, E.M.Green, P.K.Dominik, M.Bridges, J.P.Armache, D.Deneka, S.S.Kim, W.Hubbell, A.A.Kossiakoff, Y.Cheng, R.M.Stroud. Structural Basis For Activation of Voltage Sensor Domains in An Ion Channel TPC1. Proc. Natl. Acad. Sci. V. 115 E9095 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30190435
DOI: 10.1073/PNAS.1805651115