Calcium in PDB 6e1o: AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0

The binding sites of Calcium atom in the AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0 (pdb code 6e1o). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0, PDB code: 6e1o:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca801 b:78.4 occ:1.00 OE2 B:GLU514 2.5 68.5 1.0 OD1 B:ASP547 2.5 77.2 1.0 OE1 B:GLU445 2.6 87.7 1.0 CD B:GLU445 3.0 87.7 1.0 OE2 B:GLU445 3.1 87.7 1.0 OD1 B:ASP511 3.1 65.2 1.0 CD B:GLU514 3.3 68.5 1.0 CG B:ASP547 3.4 77.2 1.0 NZ B:LYS550 3.4 83.1 1.0 OE1 B:GLU514 3.6 68.5 1.0 OD2 B:ASP547 3.6 77.2 1.0 CG B:ASP511 3.9 65.2 1.0 CD B:LYS550 4.0 83.1 1.0 CG B:GLU445 4.2 87.7 1.0 OD2 B:ASP511 4.2 65.2 1.0 CE B:LYS550 4.3 83.1 1.0 CG B:GLU514 4.6 68.5 1.0 CB B:GLU445 4.7 87.7 1.0 CB B:ASP547 4.7 77.2 1.0 CA B:CA802 4.8 72.3 1.0 CB B:ASP511 4.9 65.2 1.0 OE2 B:GLU543 5.0 75.5 1.0

Calcium binding site 2 out of 4 in the AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca802 b:72.3 occ:1.00 OE2 B:GLU445 2.7 87.7 1.0 OE1 B:GLU514 3.1 68.5 1.0 CD B:GLU514 3.5 68.5 1.0 OE2 B:GLU543 3.5 75.5 1.0 CD B:GLU445 3.6 87.7 1.0 OE2 B:GLU514 3.6 68.5 1.0 CD B:GLU543 3.7 75.5 1.0 OE1 B:GLU445 4.0 87.7 1.0 CG B:GLU543 4.1 75.5 1.0 OE1 B:GLU543 4.1 75.5 1.0 CG B:GLU514 4.5 68.5 1.0 OE1 B:GLN438 4.6 72.5 1.0 O B:GLY441 4.6 80.5 1.0 CG B:GLU445 4.7 87.7 1.0 CA B:CA801 4.8 78.4 1.0 OD1 B:ASN539 4.9 70.3 1.0 C B:GLY441 4.9 80.5 1.0 CB B:GLU543 5.0 75.5 1.0 ND2 B:ASN539 5.0 70.3 1.0 CB B:GLU514 5.0 68.5 1.0

Calcium binding site 3 out of 4 in the AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca801 b:77.2 occ:1.00 OE2 A:GLU514 2.5 68.2 1.0 OD1 A:ASP547 2.5 77.2 1.0 OE1 A:GLU445 2.6 86.7 1.0 CD A:GLU445 3.0 86.7 1.0 OE2 A:GLU445 3.1 86.7 1.0 OD1 A:ASP511 3.1 64.4 1.0 CD A:GLU514 3.3 68.2 1.0 CG A:ASP547 3.4 77.2 1.0 NZ A:LYS550 3.4 82.5 1.0 OE1 A:GLU514 3.6 68.2 1.0 OD2 A:ASP547 3.6 77.2 1.0 CG A:ASP511 3.9 64.4 1.0 CD A:LYS550 4.0 82.5 1.0 CG A:GLU445 4.2 86.7 1.0 OD2 A:ASP511 4.2 64.4 1.0 CE A:LYS550 4.3 82.5 1.0 CG A:GLU514 4.6 68.2 1.0 CB A:GLU445 4.7 86.7 1.0 CB A:ASP547 4.7 77.2 1.0 CA A:CA802 4.8 72.3 1.0 CB A:ASP511 4.9 64.4 1.0 OE2 A:GLU543 5.0 75.5 1.0

Calcium binding site 4 out of 4 in the AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of AFTMEM16 Reconstituted in Nanodiscs in the Presence of CA2+ and Ceramide 24:0 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca802 b:72.3 occ:1.00 OE2 A:GLU445 2.7 86.7 1.0 OE1 A:GLU514 3.1 68.2 1.0 CD A:GLU514 3.5 68.2 1.0 OE2 A:GLU543 3.5 75.5 1.0 CD A:GLU445 3.6 86.7 1.0 OE2 A:GLU514 3.6 68.2 1.0 CD A:GLU543 3.7 75.5 1.0 OE1 A:GLU445 4.0 86.7 1.0 CG A:GLU543 4.1 75.5 1.0 OE1 A:GLU543 4.1 75.5 1.0 CG A:GLU514 4.5 68.2 1.0 OE1 A:GLN438 4.6 72.7 1.0 O A:GLY441 4.6 80.4 1.0 CG A:GLU445 4.7 86.7 1.0 CA A:CA801 4.8 77.2 1.0 OD1 A:ASN539 4.9 70.0 1.0 C A:GLY441 4.9 80.4 1.0 CB A:GLU543 5.0 75.5 1.0 ND2 A:ASN539 5.0 70.0 1.0 CB A:GLU514 5.0 68.2 1.0

M.E.Falzone, J.Rheinberger, B.C.Lee, T.Peyear, L.Sasset, A.M.Raczkowski, E.T.Eng, A.Di Lorenzo, O.S.Andersen, C.M.Nimigean, A.Accardi. Structural Basis of CA2+-Dependent Activation and Lipid Transport By A TMEM16 Scramblase. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 30648972
DOI: 10.7554/ELIFE.43229