Calcium in PDB 6f1c: C1RC1S Complex
Enzymatic activity of C1RC1S Complex
Protein crystallography data
The structure of C1RC1S Complex, PDB code: 6f1c
was solved by
J.O.M.Almitairi,
U.Venkatraman Girija,
C.M.Furze,
X.Simpson-Gray,
F.Badakshi,
J.E.Marshall,
D.A.Mitchell,
P.C.E.Moody,
R.Wallis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
97.75 /
4.20
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
96.779,
124.265,
195.499,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
24.7 /
30.5
|
Other elements in 6f1c:
The structure of C1RC1S Complex also contains other interesting chemical elements:
Calcium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Calcium atom in the C1RC1S Complex
(pdb code 6f1c). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 12 binding sites of Calcium where determined in the
C1RC1S Complex, PDB code: 6f1c:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Calcium binding site 1 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 1 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca301
b:0.6
occ:1.00
|
OD1
|
A:ASN105
|
2.5
|
0.0
|
1.0
|
|
OD1
|
A:ASP102
|
2.5
|
0.8
|
1.0
|
|
O
|
A:SER104
|
2.8
|
0.3
|
1.0
|
|
O
|
A:ASP102
|
2.8
|
0.6
|
1.0
|
|
OD1
|
A:ASN23
|
2.8
|
0.8
|
1.0
|
|
OE1
|
A:GLU49
|
3.0
|
0.3
|
1.0
|
|
C
|
A:SER104
|
3.1
|
0.1
|
1.0
|
|
OD1
|
A:ASP57
|
3.1
|
0.1
|
1.0
|
|
OD2
|
A:ASP57
|
3.3
|
0.6
|
1.0
|
|
CG
|
A:ASN105
|
3.4
|
0.1
|
1.0
|
|
C
|
A:ASP102
|
3.4
|
0.6
|
1.0
|
|
N
|
A:ASN105
|
3.4
|
0.9
|
1.0
|
|
CG2
|
A:THR101
|
3.4
|
0.1
|
1.0
|
|
CG
|
A:ASP102
|
3.6
|
0.4
|
1.0
|
|
N
|
A:SER104
|
3.6
|
0.8
|
1.0
|
|
CG
|
A:ASP57
|
3.6
|
0.8
|
1.0
|
|
N
|
A:ASP102
|
3.7
|
0.1
|
1.0
|
|
CA
|
A:ASN105
|
3.7
|
1.0
|
1.0
|
|
CB
|
A:ASN105
|
3.8
|
0.5
|
1.0
|
|
CG
|
A:ASN23
|
3.9
|
0.1
|
1.0
|
|
CA
|
A:ASP102
|
4.0
|
0.6
|
1.0
|
|
CA
|
A:SER104
|
4.0
|
0.1
|
1.0
|
|
CD
|
A:GLU49
|
4.0
|
0.7
|
1.0
|
|
C
|
A:PHE103
|
4.1
|
0.4
|
1.0
|
|
N
|
A:PHE103
|
4.3
|
0.9
|
1.0
|
|
C
|
A:THR101
|
4.3
|
0.5
|
1.0
|
|
OD2
|
A:ASP102
|
4.4
|
0.6
|
1.0
|
|
CB
|
A:ASP102
|
4.4
|
0.1
|
1.0
|
|
OE2
|
A:GLU49
|
4.5
|
0.7
|
1.0
|
|
ND2
|
A:ASN105
|
4.5
|
0.7
|
1.0
|
|
CB
|
A:THR101
|
4.6
|
0.8
|
1.0
|
|
CA
|
A:THR101
|
4.6
|
0.4
|
1.0
|
|
CB
|
A:ASN23
|
4.7
|
0.5
|
1.0
|
|
O
|
A:PHE103
|
4.7
|
0.1
|
1.0
|
|
CA
|
A:PHE103
|
4.7
|
0.8
|
1.0
|
|
ND2
|
A:ASN23
|
4.9
|
0.7
|
1.0
|
|
CA
|
A:ASN23
|
5.0
|
0.9
|
1.0
|
|
Calcium binding site 2 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 2 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca302
b:0.0
occ:1.00
|
O
|
A:TYR151
|
2.4
|
0.8
|
1.0
|
|
OE2
|
A:GLU128
|
2.5
|
0.2
|
1.0
|
|
OD1
|
A:ASP125
|
2.5
|
0.8
|
1.0
|
|
OE1
|
A:GLU128
|
2.6
|
0.9
|
1.0
|
|
O
|
A:GLY154
|
2.7
|
0.7
|
1.0
|
|
CD
|
A:GLU128
|
2.9
|
0.4
|
1.0
|
|
O
|
A:LEU126
|
3.0
|
0.5
|
1.0
|
|
OD2
|
A:ASP125
|
3.2
|
0.9
|
1.0
|
|
CG
|
A:ASP125
|
3.2
|
0.7
|
1.0
|
|
OD1
|
A:ASN150
|
3.4
|
0.9
|
1.0
|
|
O
|
A:GLY153
|
3.5
|
0.7
|
1.0
|
|
C
|
A:GLY154
|
3.6
|
0.7
|
1.0
|
|
C
|
A:GLY153
|
3.6
|
0.4
|
1.0
|
|
C
|
A:TYR151
|
3.7
|
0.6
|
1.0
|
|
N
|
A:GLY153
|
3.8
|
0.0
|
1.0
|
|
N
|
A:GLY154
|
3.9
|
0.9
|
1.0
|
|
CA
|
A:GLY154
|
4.1
|
0.3
|
1.0
|
|
N
|
A:TYR151
|
4.2
|
0.1
|
1.0
|
|
C
|
A:VAL152
|
4.2
|
0.6
|
1.0
|
|
C
|
A:LEU126
|
4.2
|
0.5
|
1.0
|
|
CA
|
A:GLY153
|
4.3
|
0.8
|
1.0
|
|
CG
|
A:GLU128
|
4.4
|
0.0
|
1.0
|
|
CA
|
A:VAL152
|
4.5
|
0.0
|
1.0
|
|
N
|
A:VAL152
|
4.6
|
0.6
|
1.0
|
|
CA
|
A:TYR151
|
4.6
|
0.8
|
1.0
|
|
CG
|
A:ASN150
|
4.6
|
0.3
|
1.0
|
|
N
|
A:LEU126
|
4.6
|
0.5
|
1.0
|
|
N
|
A:TYR155
|
4.6
|
0.9
|
1.0
|
|
CB
|
A:ASP125
|
4.7
|
0.7
|
1.0
|
|
O
|
A:GLY36
|
4.8
|
0.3
|
1.0
|
|
CB
|
A:TYR155
|
4.8
|
0.7
|
1.0
|
|
O
|
A:VAL152
|
4.8
|
0.0
|
1.0
|
|
N
|
A:GLU128
|
5.0
|
0.0
|
1.0
|
|
Calcium binding site 3 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 3 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca303
b:0.1
occ:1.00
|
OD2
|
A:ASP226
|
2.4
|
0.8
|
1.0
|
|
O
|
A:SER275
|
2.5
|
0.7
|
1.0
|
|
OD1
|
A:ASP273
|
2.5
|
0.6
|
1.0
|
|
OD2
|
A:ASP236
|
2.6
|
0.6
|
1.0
|
|
OD2
|
A:ASP273
|
3.0
|
0.2
|
1.0
|
|
CG
|
A:ASP273
|
3.1
|
0.3
|
1.0
|
|
OH
|
A:TYR197
|
3.3
|
0.0
|
1.0
|
|
CE1
|
A:TYR197
|
3.4
|
0.2
|
1.0
|
|
C
|
A:SER275
|
3.5
|
0.3
|
1.0
|
|
CG
|
A:ASP226
|
3.5
|
0.8
|
1.0
|
|
CG
|
A:ASP236
|
3.6
|
0.9
|
1.0
|
|
OD1
|
A:ASP236
|
3.8
|
0.1
|
1.0
|
|
CZ
|
A:TYR197
|
3.8
|
0.3
|
1.0
|
|
CA
|
A:GLY276
|
4.0
|
0.5
|
1.0
|
|
CB
|
A:ASP226
|
4.0
|
0.4
|
1.0
|
|
N
|
A:ASP277
|
4.2
|
0.8
|
1.0
|
|
OG
|
A:SER275
|
4.2
|
0.7
|
1.0
|
|
N
|
A:GLY276
|
4.2
|
0.9
|
1.0
|
|
CB
|
A:ASP273
|
4.5
|
0.3
|
1.0
|
|
CD1
|
A:TYR197
|
4.6
|
0.5
|
1.0
|
|
OD1
|
A:ASP226
|
4.6
|
0.2
|
1.0
|
|
CA
|
A:SER275
|
4.6
|
0.8
|
1.0
|
|
C
|
A:GLY276
|
4.6
|
0.6
|
1.0
|
|
N
|
A:SER275
|
4.8
|
0.9
|
1.0
|
|
CB
|
A:SER275
|
4.9
|
0.4
|
1.0
|
|
CB
|
A:ASP236
|
4.9
|
0.0
|
1.0
|
|
N
|
A:ASP273
|
5.0
|
0.6
|
1.0
|
|
Calcium binding site 4 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 4 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca301
b:0.2
occ:1.00
|
OD1
|
C:ASN105
|
2.3
|
0.1
|
1.0
|
|
OD1
|
C:ASP57
|
2.7
|
0.4
|
1.0
|
|
N
|
C:ASP102
|
2.8
|
0.6
|
1.0
|
|
CB
|
C:ASP102
|
2.8
|
0.4
|
1.0
|
|
CA
|
C:ASP102
|
2.9
|
0.2
|
1.0
|
|
C
|
C:ASP102
|
2.9
|
0.9
|
1.0
|
|
O
|
C:ASP102
|
3.0
|
0.3
|
1.0
|
|
OE1
|
C:GLU49
|
3.2
|
0.8
|
1.0
|
|
O
|
C:SER104
|
3.2
|
0.6
|
1.0
|
|
CG
|
C:ASP102
|
3.5
|
0.5
|
1.0
|
|
CG
|
C:ASN105
|
3.5
|
0.6
|
1.0
|
|
CG
|
C:ASP57
|
3.6
|
0.8
|
1.0
|
|
C
|
C:SER104
|
3.6
|
0.9
|
1.0
|
|
N
|
C:SER104
|
3.7
|
0.5
|
1.0
|
|
OD2
|
C:ASP57
|
3.8
|
0.3
|
1.0
|
|
N
|
C:PHE103
|
3.8
|
0.2
|
1.0
|
|
C
|
C:THR101
|
3.8
|
0.1
|
1.0
|
|
OD2
|
C:ASP102
|
3.9
|
0.7
|
1.0
|
|
OD1
|
C:ASN23
|
3.9
|
0.8
|
1.0
|
|
CG2
|
C:THR101
|
4.0
|
0.3
|
1.0
|
|
N
|
C:ASN105
|
4.2
|
0.2
|
1.0
|
|
CD1
|
C:TYR56
|
4.2
|
0.2
|
1.0
|
|
ND2
|
C:ASN105
|
4.3
|
0.8
|
1.0
|
|
OD1
|
C:ASP102
|
4.3
|
0.3
|
1.0
|
|
CD
|
C:GLU49
|
4.3
|
0.1
|
1.0
|
|
CA
|
C:SER104
|
4.3
|
0.2
|
1.0
|
|
C
|
C:PHE103
|
4.3
|
0.3
|
1.0
|
|
CA
|
C:THR101
|
4.4
|
0.7
|
1.0
|
|
O
|
C:TYR56
|
4.5
|
0.4
|
1.0
|
|
CA
|
C:ASN105
|
4.5
|
0.3
|
1.0
|
|
CB
|
C:TYR56
|
4.5
|
0.3
|
1.0
|
|
CA
|
C:PHE103
|
4.6
|
0.5
|
1.0
|
|
CB
|
C:ASN105
|
4.6
|
0.2
|
1.0
|
|
C
|
C:TYR56
|
4.6
|
0.6
|
1.0
|
|
OE2
|
C:GLU49
|
4.7
|
0.9
|
1.0
|
|
O
|
C:THR101
|
4.7
|
0.8
|
1.0
|
|
CB
|
C:THR101
|
4.8
|
0.9
|
1.0
|
|
CG
|
C:TYR56
|
4.8
|
1.0
|
1.0
|
|
CA
|
C:TYR56
|
5.0
|
0.6
|
1.0
|
|
Calcium binding site 5 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 5 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca302
b:0.9
occ:1.00
|
O
|
C:TYR151
|
2.4
|
0.5
|
1.0
|
|
OD1
|
C:ASP125
|
2.5
|
0.6
|
1.0
|
|
OE1
|
C:GLU128
|
2.6
|
0.5
|
1.0
|
|
OE2
|
C:GLU128
|
2.6
|
0.9
|
1.0
|
|
O
|
C:GLY154
|
2.8
|
0.8
|
1.0
|
|
O
|
C:LEU126
|
2.9
|
0.1
|
1.0
|
|
CD
|
C:GLU128
|
2.9
|
0.1
|
1.0
|
|
OD2
|
C:ASP125
|
3.0
|
0.1
|
1.0
|
|
OD1
|
C:ASN150
|
3.1
|
0.7
|
1.0
|
|
CG
|
C:ASP125
|
3.1
|
0.2
|
1.0
|
|
C
|
C:TYR151
|
3.7
|
0.2
|
1.0
|
|
C
|
C:GLY154
|
3.7
|
0.6
|
1.0
|
|
O
|
C:GLY153
|
3.8
|
0.9
|
1.0
|
|
C
|
C:GLY153
|
3.9
|
0.4
|
1.0
|
|
N
|
C:GLY153
|
4.0
|
0.9
|
1.0
|
|
N
|
C:TYR151
|
4.0
|
0.2
|
1.0
|
|
C
|
C:LEU126
|
4.1
|
0.2
|
1.0
|
|
N
|
C:GLY154
|
4.1
|
0.3
|
1.0
|
|
CA
|
C:GLY154
|
4.3
|
0.8
|
1.0
|
|
CG
|
C:ASN150
|
4.3
|
0.6
|
1.0
|
|
C
|
C:VAL152
|
4.4
|
0.9
|
1.0
|
|
CG
|
C:GLU128
|
4.4
|
0.1
|
1.0
|
|
CA
|
C:GLY153
|
4.5
|
0.3
|
1.0
|
|
N
|
C:LEU126
|
4.5
|
0.2
|
1.0
|
|
CA
|
C:TYR151
|
4.5
|
0.9
|
1.0
|
|
N
|
C:VAL152
|
4.6
|
0.8
|
1.0
|
|
CA
|
C:VAL152
|
4.6
|
0.3
|
1.0
|
|
CB
|
C:ASP125
|
4.6
|
0.2
|
1.0
|
|
N
|
C:TYR155
|
4.7
|
0.7
|
1.0
|
|
N
|
C:GLU128
|
4.8
|
0.1
|
1.0
|
|
CB
|
C:TYR155
|
4.8
|
0.4
|
1.0
|
|
CA
|
C:ASN150
|
4.9
|
0.2
|
1.0
|
|
C
|
C:ASN150
|
4.9
|
0.3
|
1.0
|
|
CA
|
C:LEU126
|
4.9
|
0.9
|
1.0
|
|
Calcium binding site 6 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 6 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca303
b:0.3
occ:1.00
|
O
|
C:SER275
|
2.4
|
0.7
|
1.0
|
|
OD2
|
C:ASP226
|
2.4
|
0.9
|
1.0
|
|
OD1
|
C:ASP273
|
2.6
|
0.8
|
1.0
|
|
OD2
|
C:ASP236
|
2.7
|
0.1
|
1.0
|
|
OD2
|
C:ASP273
|
2.9
|
0.5
|
1.0
|
|
CG
|
C:ASP273
|
3.1
|
0.8
|
1.0
|
|
OH
|
C:TYR197
|
3.4
|
0.9
|
1.0
|
|
C
|
C:SER275
|
3.4
|
0.6
|
1.0
|
|
CE1
|
C:TYR197
|
3.5
|
0.7
|
1.0
|
|
CG
|
C:ASP226
|
3.6
|
1.0
|
1.0
|
|
CG
|
C:ASP236
|
3.7
|
0.8
|
1.0
|
|
CZ
|
C:TYR197
|
3.9
|
0.7
|
1.0
|
|
OD1
|
C:ASP236
|
3.9
|
0.4
|
1.0
|
|
CA
|
C:GLY276
|
3.9
|
0.7
|
1.0
|
|
CB
|
C:ASP226
|
4.1
|
0.1
|
1.0
|
|
OG
|
C:SER275
|
4.1
|
0.1
|
1.0
|
|
N
|
C:GLY276
|
4.1
|
0.0
|
1.0
|
|
N
|
C:ASP277
|
4.2
|
0.5
|
1.0
|
|
CB
|
C:ASP273
|
4.5
|
0.5
|
1.0
|
|
CA
|
C:SER275
|
4.5
|
0.8
|
1.0
|
|
OD1
|
C:ASP226
|
4.6
|
0.4
|
1.0
|
|
C
|
C:GLY276
|
4.6
|
1.0
|
1.0
|
|
CD1
|
C:TYR197
|
4.6
|
0.9
|
1.0
|
|
N
|
C:SER275
|
4.7
|
0.1
|
1.0
|
|
CB
|
C:SER275
|
4.8
|
0.7
|
1.0
|
|
Calcium binding site 7 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 7 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca301
b:0.8
occ:1.00
|
OD1
|
D:ASP98
|
2.4
|
0.9
|
1.0
|
|
O
|
D:SER100
|
2.5
|
0.8
|
1.0
|
|
OD1
|
D:ASN101
|
2.5
|
0.2
|
1.0
|
|
O
|
D:ASP98
|
2.8
|
0.9
|
1.0
|
|
OD2
|
D:ASP53
|
2.8
|
0.3
|
1.0
|
|
OE1
|
D:GLU45
|
3.1
|
0.9
|
1.0
|
|
OD1
|
D:ASP53
|
3.2
|
0.5
|
1.0
|
|
C
|
D:SER100
|
3.3
|
0.7
|
1.0
|
|
CG
|
D:ASP53
|
3.4
|
0.4
|
1.0
|
|
CG
|
D:ASN101
|
3.4
|
0.1
|
1.0
|
|
C
|
D:ASP98
|
3.5
|
0.2
|
1.0
|
|
N
|
D:ASP98
|
3.6
|
0.6
|
1.0
|
|
CG
|
D:ASP98
|
3.6
|
0.1
|
1.0
|
|
N
|
D:SER100
|
3.7
|
0.1
|
1.0
|
|
OG
|
D:SER19
|
3.8
|
0.4
|
1.0
|
|
ND2
|
D:ASN101
|
4.0
|
1.0
|
1.0
|
|
CB
|
D:SER97
|
4.0
|
0.2
|
1.0
|
|
CA
|
D:ASP98
|
4.0
|
0.3
|
1.0
|
|
N
|
D:ASN101
|
4.1
|
0.1
|
1.0
|
|
CA
|
D:SER100
|
4.1
|
0.5
|
1.0
|
|
C
|
D:SER97
|
4.2
|
0.8
|
1.0
|
|
CD
|
D:GLU45
|
4.3
|
0.3
|
1.0
|
|
CB
|
D:SER19
|
4.3
|
0.9
|
1.0
|
|
N
|
D:PHE99
|
4.4
|
0.5
|
1.0
|
|
CB
|
D:ASP98
|
4.4
|
0.9
|
1.0
|
|
CA
|
D:ASN101
|
4.4
|
0.5
|
1.0
|
|
OG
|
D:SER97
|
4.4
|
0.9
|
1.0
|
|
CA
|
D:SER97
|
4.4
|
0.2
|
1.0
|
|
CB
|
D:ASN101
|
4.5
|
1.0
|
1.0
|
|
CE1
|
D:TYR17
|
4.5
|
0.8
|
1.0
|
|
C
|
D:PHE99
|
4.5
|
0.8
|
1.0
|
|
OD2
|
D:ASP98
|
4.5
|
0.9
|
1.0
|
|
CA
|
D:SER19
|
4.6
|
0.8
|
1.0
|
|
OE2
|
D:GLU45
|
4.9
|
0.7
|
1.0
|
|
CB
|
D:ASP53
|
4.9
|
0.5
|
1.0
|
|
CA
|
D:PHE99
|
4.9
|
0.0
|
1.0
|
|
O
|
D:SER97
|
5.0
|
0.9
|
1.0
|
|
Calcium binding site 8 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 8 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca303
b:0.8
occ:1.00
|
OD1
|
D:ASP116
|
2.4
|
0.4
|
1.0
|
|
OE2
|
D:GLU119
|
2.5
|
0.9
|
1.0
|
|
O
|
D:ILE117
|
2.5
|
0.9
|
1.0
|
|
O
|
D:PHE135
|
2.7
|
0.6
|
1.0
|
|
OE1
|
D:GLU119
|
2.8
|
0.0
|
1.0
|
|
O
|
D:GLY138
|
2.8
|
0.6
|
1.0
|
|
N
|
D:GLY138
|
2.8
|
0.8
|
1.0
|
|
CD
|
D:GLU119
|
3.0
|
0.2
|
1.0
|
|
OD1
|
D:ASN134
|
3.2
|
0.4
|
1.0
|
|
CA
|
D:GLY138
|
3.3
|
0.9
|
1.0
|
|
C
|
D:GLY138
|
3.3
|
0.1
|
1.0
|
|
CG
|
D:ASP116
|
3.4
|
0.8
|
1.0
|
|
N
|
D:GLY137
|
3.6
|
0.6
|
1.0
|
|
C
|
D:GLY137
|
3.6
|
0.6
|
1.0
|
|
OD2
|
D:ASP116
|
3.6
|
0.8
|
1.0
|
|
C
|
D:ILE117
|
3.7
|
0.1
|
1.0
|
|
CA
|
D:GLY137
|
4.0
|
0.7
|
1.0
|
|
C
|
D:PHE135
|
4.0
|
0.4
|
1.0
|
|
N
|
D:ILE117
|
4.1
|
0.1
|
1.0
|
|
O
|
D:GLY32
|
4.1
|
0.6
|
1.0
|
|
CA
|
D:ILE117
|
4.3
|
0.4
|
1.0
|
|
CG
|
D:ASN134
|
4.4
|
0.0
|
1.0
|
|
O
|
D:GLY137
|
4.4
|
0.0
|
1.0
|
|
CG
|
D:GLU119
|
4.5
|
0.1
|
1.0
|
|
C
|
D:ILE136
|
4.5
|
1.0
|
1.0
|
|
N
|
D:PHE135
|
4.5
|
0.7
|
1.0
|
|
N
|
D:TYR139
|
4.6
|
0.7
|
1.0
|
|
CB
|
D:ILE117
|
4.6
|
0.2
|
1.0
|
|
CB
|
D:ASP116
|
4.7
|
0.1
|
1.0
|
|
CA
|
D:ILE136
|
4.7
|
0.5
|
1.0
|
|
N
|
D:ASN118
|
4.8
|
0.2
|
1.0
|
|
N
|
D:ILE136
|
4.8
|
0.9
|
1.0
|
|
N
|
D:GLU119
|
4.9
|
0.6
|
1.0
|
|
C
|
D:ASP116
|
4.9
|
0.3
|
1.0
|
|
CA
|
D:PHE135
|
4.9
|
0.4
|
1.0
|
|
Calcium binding site 9 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 9 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca304
b:0.1
occ:1.00
|
OD1
|
D:ASP260
|
2.5
|
0.5
|
1.0
|
|
OE1
|
D:GLN264
|
2.6
|
0.3
|
1.0
|
|
OD2
|
D:ASP221
|
2.6
|
0.2
|
1.0
|
|
O
|
D:GLY263
|
2.9
|
0.8
|
1.0
|
|
O
|
D:THR262
|
3.0
|
1.0
|
1.0
|
|
O
|
D:ASP260
|
3.1
|
0.8
|
1.0
|
|
C
|
D:GLY263
|
3.4
|
0.0
|
1.0
|
|
CG
|
D:ASP221
|
3.4
|
0.8
|
1.0
|
|
OD1
|
D:ASP221
|
3.5
|
0.2
|
1.0
|
|
OE1
|
D:GLU211
|
3.5
|
0.8
|
1.0
|
|
C
|
D:THR262
|
3.5
|
0.7
|
1.0
|
|
CD
|
D:GLN264
|
3.5
|
1.0
|
1.0
|
|
N
|
D:ASP260
|
3.6
|
0.4
|
1.0
|
|
C
|
D:ASP260
|
3.7
|
0.5
|
1.0
|
|
CG
|
D:ASP260
|
3.7
|
0.5
|
1.0
|
|
CG
|
D:GLN264
|
3.8
|
0.1
|
1.0
|
|
N
|
D:GLN264
|
4.0
|
0.4
|
1.0
|
|
N
|
D:GLY263
|
4.0
|
0.5
|
1.0
|
|
CA
|
D:GLY263
|
4.1
|
0.8
|
1.0
|
|
CA
|
D:ASP260
|
4.1
|
0.0
|
1.0
|
|
N
|
D:THR262
|
4.1
|
0.5
|
1.0
|
|
CB
|
D:THR259
|
4.2
|
0.8
|
1.0
|
|
CA
|
D:THR262
|
4.2
|
0.9
|
1.0
|
|
CA
|
D:GLN264
|
4.2
|
0.1
|
1.0
|
|
CE1
|
D:TYR181
|
4.3
|
0.7
|
1.0
|
|
C
|
D:THR259
|
4.5
|
0.0
|
1.0
|
|
CB
|
D:ASP260
|
4.5
|
0.6
|
1.0
|
|
C
|
D:LEU261
|
4.5
|
0.4
|
1.0
|
|
N
|
D:LEU261
|
4.5
|
0.9
|
1.0
|
|
CA
|
D:THR259
|
4.6
|
0.9
|
1.0
|
|
OD2
|
D:ASP260
|
4.6
|
0.4
|
1.0
|
|
CD
|
D:GLU211
|
4.6
|
0.8
|
1.0
|
|
NE2
|
D:GLN264
|
4.6
|
0.5
|
1.0
|
|
CB
|
D:GLN264
|
4.7
|
0.2
|
1.0
|
|
CB
|
D:ASP221
|
4.8
|
0.9
|
1.0
|
|
OH
|
D:TYR181
|
4.8
|
0.9
|
1.0
|
|
O
|
D:LEU261
|
4.9
|
0.1
|
1.0
|
|
CB
|
D:GLU183
|
5.0
|
0.2
|
1.0
|
|
CG2
|
D:THR259
|
5.0
|
0.8
|
1.0
|
|
Calcium binding site 10 out
of 12 in 6f1c
Go back to
Calcium Binding Sites List in 6f1c
Calcium binding site 10 out
of 12 in the C1RC1S Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 10 of C1RC1S Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca301
b:0.5
occ:1.00
|
OD1
|
B:ASP98
|
2.5
|
0.4
|
1.0
|
|
OD1
|
B:ASN101
|
2.5
|
0.6
|
1.0
|
|
OD2
|
B:ASP53
|
2.7
|
1.0
|
1.0
|
|
O
|
B:SER100
|
2.7
|
0.9
|
1.0
|
|
O
|
B:ASP98
|
2.7
|
0.5
|
1.0
|
|
OD1
|
B:ASP53
|
3.0
|
0.9
|
1.0
|
|
OE1
|
B:GLU45
|
3.2
|
0.2
|
1.0
|
|
CG
|
B:ASP53
|
3.2
|
0.1
|
1.0
|
|
C
|
B:ASP98
|
3.4
|
0.1
|
1.0
|
|
CG
|
B:ASN101
|
3.5
|
0.2
|
1.0
|
|
C
|
B:SER100
|
3.5
|
0.9
|
1.0
|
|
N
|
B:ASP98
|
3.5
|
0.1
|
1.0
|
|
CG
|
B:ASP98
|
3.7
|
0.7
|
1.0
|
|
N
|
B:SER100
|
3.8
|
0.8
|
1.0
|
|
CB
|
B:SER97
|
3.8
|
1.0
|
1.0
|
|
OG
|
B:SER19
|
3.9
|
0.8
|
1.0
|
|
CA
|
B:ASP98
|
3.9
|
0.0
|
1.0
|
|
ND2
|
B:ASN101
|
4.0
|
0.4
|
1.0
|
|
C
|
B:SER97
|
4.1
|
0.3
|
1.0
|
|
CA
|
B:SER100
|
4.3
|
0.1
|
1.0
|
|
N
|
B:ASN101
|
4.3
|
1.0
|
1.0
|
|
OG
|
B:SER97
|
4.3
|
0.6
|
1.0
|
|
CA
|
B:SER97
|
4.3
|
0.3
|
1.0
|
|
CB
|
B:SER19
|
4.4
|
0.8
|
1.0
|
|
CE1
|
B:TYR17
|
4.4
|
1.0
|
1.0
|
|
N
|
B:PHE99
|
4.4
|
0.2
|
1.0
|
|
CB
|
B:ASP98
|
4.4
|
0.6
|
1.0
|
|
CD
|
B:GLU45
|
4.4
|
0.2
|
1.0
|
|
CA
|
B:SER19
|
4.6
|
0.8
|
1.0
|
|
C
|
B:PHE99
|
4.6
|
0.5
|
1.0
|
|
CA
|
B:ASN101
|
4.6
|
0.8
|
1.0
|
|
OD2
|
B:ASP98
|
4.6
|
0.7
|
1.0
|
|
CB
|
B:ASN101
|
4.6
|
0.6
|
1.0
|
|
CB
|
B:ASP53
|
4.7
|
0.5
|
1.0
|
|
O
|
B:SER97
|
4.9
|
0.9
|
1.0
|
|
CA
|
B:PHE99
|
4.9
|
0.6
|
1.0
|
|
Reference:
J.O.M.Almitairi,
U.Venkatraman Girija,
C.M.Furze,
X.Simpson-Gray,
F.Badakshi,
J.E.Marshall,
W.J.Schwaeble,
D.A.Mitchell,
P.C.E.Moody,
R.Wallis.
Structure of the C1R-C1S Interaction of the C1 Complex of Complement Activation. Proc. Natl. Acad. Sci. V. 115 768 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29311313
DOI: 10.1073/PNAS.1718709115
Page generated: Sat Dec 12 06:05:42 2020
|
