Calcium in PDB 6feh: Solution Structure of Cam/KV7.2-Hab Complex

The binding sites of Calcium atom in the Solution Structure of Cam/KV7.2-Hab Complex (pdb code 6feh). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Solution Structure of Cam/KV7.2-Hab Complex, PDB code: 6feh:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Solution Structure of Cam/KV7.2-Hab Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Solution Structure of Cam/KV7.2-Hab Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca301 b:0.0 occ:1.00 OD1 B:ASP20 2.1 0.0 1.0 OD1 B:ASP22 2.1 0.0 1.0 OD1 B:ASP24 2.2 0.0 1.0 OE2 B:GLU31 2.2 0.0 1.0 O B:THR26 2.3 0.0 1.0 OE1 B:GLU31 2.3 0.0 1.0 CD B:GLU31 2.6 0.0 1.0 CG B:ASP22 3.1 0.0 1.0 CG B:ASP24 3.2 0.0 1.0 H B:ASP24 3.2 0.0 1.0 CG B:ASP20 3.3 0.0 1.0 H B:THR26 3.4 0.0 1.0 C B:THR26 3.5 0.0 1.0 OD2 B:ASP22 3.5 0.0 1.0 HA B:ILE27 3.5 0.0 1.0 H B:GLY23 3.6 0.0 1.0 H B:ASP22 3.6 0.0 1.0 H B:LYS21 3.7 0.0 1.0 OD2 B:ASP24 3.8 0.0 1.0 HA B:ASP20 3.8 0.0 1.0 H B:THR28 4.0 0.0 1.0 CG B:GLU31 4.0 0.0 1.0 N B:ASP24 4.1 0.0 1.0 OD2 B:ASP20 4.1 0.0 1.0 N B:THR26 4.2 0.0 1.0 N B:GLY23 4.2 0.0 1.0 H B:GLY25 4.2 0.0 1.0 HG23 B:THR26 4.2 0.0 1.0 HG3 B:GLU31 4.2 0.0 1.0 N B:ASP22 4.3 0.0 1.0 CB B:ASP24 4.3 0.0 1.0 CB B:ASP20 4.3 0.0 1.0 N B:ILE27 4.3 0.0 1.0 CA B:ILE27 4.3 0.0 1.0 CB B:ASP22 4.4 0.0 1.0 HG22 B:THR28 4.4 0.0 1.0 N B:LYS21 4.4 0.0 1.0 HG2 B:GLU31 4.4 0.0 1.0 CA B:THR26 4.4 0.0 1.0 HB3 B:ASP24 4.5 0.0 1.0 CA B:ASP20 4.5 0.0 1.0 HB2 B:ASP20 4.5 0.0 1.0 CA B:ASP24 4.6 0.0 1.0 N B:THR28 4.6 0.0 1.0 CA B:ASP22 4.7 0.0 1.0 N B:GLY25 4.7 0.0 1.0 HG22 B:THR26 4.7 0.0 1.0 C B:ASP22 4.8 0.0 1.0 HB3 B:ASP22 4.8 0.0 1.0 CG2 B:THR26 4.9 0.0 1.0 C B:ASP20 4.9 0.0 1.0 HB2 B:GLU31 4.9 0.0 1.0 C B:ASP24 5.0 0.0 1.0 CB B:GLU31 5.0 0.0 1.0 C B:ILE27 5.0 0.0 1.0

Calcium binding site 2 out of 4 in the Solution Structure of Cam/KV7.2-Hab Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Solution Structure of Cam/KV7.2-Hab Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca302 b:0.0 occ:1.00 OE1 B:GLU67 2.2 0.0 1.0 OD1 B:ASP56 2.2 0.0 1.0 OE2 B:GLU67 2.2 0.0 1.0 OD1 B:ASN60 2.3 0.0 1.0 OD2 B:ASP56 2.3 0.0 1.0 CD B:GLU67 2.5 0.0 1.0 CG B:ASP56 2.5 0.0 1.0 CG B:ASN60 3.4 0.0 1.0 HB3 B:ASP58 3.6 0.0 1.0 HB2 B:ASN60 3.7 0.0 1.0 H B:ASP58 3.8 0.0 1.0 CB B:ASP56 3.9 0.0 1.0 CG B:GLU67 4.0 0.0 1.0 H B:ASN60 4.0 0.0 1.0 CB B:ASN60 4.1 0.0 1.0 HB2 B:ASP56 4.2 0.0 1.0 HG2 B:GLU67 4.2 0.0 1.0 HA B:ASP56 4.3 0.0 1.0 HB3 B:ASP64 4.3 0.0 1.0 ND2 B:ASN60 4.4 0.0 1.0 HD21 B:ASN60 4.4 0.0 1.0 HG3 B:GLU67 4.5 0.0 1.0 CB B:ASP58 4.5 0.0 1.0 H B:ALA57 4.5 0.0 1.0 H B:GLY59 4.6 0.0 1.0 HB2 B:ASP58 4.6 0.0 1.0 HB3 B:ASP56 4.6 0.0 1.0 N B:ASP58 4.6 0.0 1.0 CA B:ASP56 4.7 0.0 1.0 N B:ASN60 4.7 0.0 1.0 HB2 B:ASP64 4.7 0.0 1.0 HB2 B:GLU67 4.8 0.0 1.0 HB3 B:ASN60 4.8 0.0 1.0 H B:ASP64 4.8 0.0 1.0 N B:ALA57 4.9 0.0 1.0 HB3 B:ALA57 4.9 0.0 1.0 CB B:GLU67 4.9 0.0 1.0 N B:GLY59 5.0 0.0 1.0

Calcium binding site 3 out of 4 in the Solution Structure of Cam/KV7.2-Hab Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Solution Structure of Cam/KV7.2-Hab Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca303 b:0.0 occ:1.00 OD1 B:ASP95 2.0 0.0 1.0 OD1 B:ASP93 2.1 0.0 1.0 OD2 B:ASP93 2.2 0.0 1.0 O B:TYR99 2.3 0.0 1.0 H B:TYR99 2.3 0.0 1.0 CG B:ASP93 2.5 0.0 1.0 CG B:ASP95 2.8 0.0 1.0 H B:ASN97 2.9 0.0 1.0 N B:TYR99 2.9 0.0 1.0 OD2 B:ASP95 3.0 0.0 1.0 H B:GLY98 3.0 0.0 1.0 C B:TYR99 3.1 0.0 1.0 N B:GLY98 3.3 0.0 1.0 N B:ASN97 3.5 0.0 1.0 H B:ASP95 3.6 0.0 1.0 CA B:TYR99 3.6 0.0 1.0 H B:GLY96 3.6 0.0 1.0 HB2 B:ASN97 3.7 0.0 1.0 C B:GLY98 3.8 0.0 1.0 C B:ASN97 3.8 0.0 1.0 CA B:GLY98 4.0 0.0 1.0 HA B:ILE100 4.0 0.0 1.0 N B:GLY96 4.0 0.0 1.0 CG B:TYR99 4.0 0.0 1.0 CA B:ASN97 4.0 0.0 1.0 CB B:ASP93 4.1 0.0 1.0 CD2 B:TYR99 4.1 0.0 1.0 CB B:ASP95 4.1 0.0 1.0 N B:ILE100 4.2 0.0 1.0 HZ3 B:LYS94 4.2 0.0 1.0 CD1 B:TYR99 4.3 0.0 1.0 N B:ASP95 4.3 0.0 1.0 HA2 B:GLY98 4.3 0.0 1.0 HD2 B:TYR99 4.3 0.0 1.0 CB B:ASN97 4.4 0.0 1.0 CB B:TYR99 4.4 0.0 1.0 HA B:TYR99 4.4 0.0 1.0 CE2 B:TYR99 4.4 0.0 1.0 HE2 B:TYR138 4.4 0.0 1.0 C B:ASP95 4.4 0.0 1.0 HB2 B:ASP93 4.4 0.0 1.0 HG3 B:LYS94 4.4 0.0 1.0 C B:GLY96 4.5 0.0 1.0 CA B:ASP95 4.5 0.0 1.0 HB3 B:ASP93 4.5 0.0 1.0 HA B:ASP93 4.6 0.0 1.0 CE1 B:TYR99 4.6 0.0 1.0 CA B:ILE100 4.6 0.0 1.0 HD1 B:TYR99 4.6 0.0 1.0 HB2 B:ASP95 4.6 0.0 1.0 CA B:GLY96 4.7 0.0 1.0 CZ B:TYR99 4.7 0.0 1.0 HH B:TYR138 4.7 0.0 1.0 O B:ASN97 4.7 0.0 1.0 HB3 B:ASP95 4.7 0.0 1.0 HA3 B:GLY98 4.8 0.0 1.0 O B:GLY98 4.8 0.0 1.0 HE2 B:TYR99 4.8 0.0 1.0 CA B:ASP93 4.9 0.0 1.0 HB B:ILE100 4.9 0.0 1.0 HB3 B:TYR99 4.9 0.0 1.0 HA2 B:GLY96 4.9 0.0 1.0 H B:ILE100 4.9 0.0 1.0 HA B:ASN97 5.0 0.0 1.0

Calcium binding site 4 out of 4 in the Solution Structure of Cam/KV7.2-Hab Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Solution Structure of Cam/KV7.2-Hab Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca304 b:0.0 occ:1.00 OD1 B:ASP131 1.7 0.0 1.0 O B:GLN135 1.8 0.0 1.0 OD1 B:ASP133 2.2 0.0 1.0 CG B:ASP131 2.2 0.0 1.0 OD2 B:ASP131 2.2 0.0 1.0 HG3 B:GLN135 2.8 0.0 1.0 C B:GLN135 3.0 0.0 1.0 O B:ASP133 3.3 0.0 1.0 CG B:ASP133 3.3 0.0 1.0 HA B:VAL136 3.4 0.0 1.0 HG22 B:VAL136 3.6 0.0 1.0 CB B:ASP131 3.6 0.0 1.0 CG B:GLN135 3.7 0.0 1.0 OD2 B:ASP133 3.8 0.0 1.0 H B:ASP131 3.8 0.0 1.0 HG2 B:GLN135 3.9 0.0 1.0 HB2 B:ASP131 3.9 0.0 1.0 N B:VAL136 3.9 0.0 1.0 CA B:GLN135 4.0 0.0 1.0 HE21 B:GLN135 4.0 0.0 1.0 O B:ASP131 4.1 0.0 1.0 N B:GLN135 4.1 0.0 1.0 C B:ASP133 4.1 0.0 1.0 CA B:VAL136 4.1 0.0 1.0 H B:GLN135 4.1 0.0 1.0 HG23 B:VAL136 4.1 0.0 1.0 HB3 B:ASP131 4.2 0.0 1.0 CG2 B:VAL136 4.3 0.0 1.0 CA B:ASP131 4.3 0.0 1.0 C B:ASP131 4.3 0.0 1.0 CB B:GLN135 4.4 0.0 1.0 HG23 B:ILE130 4.4 0.0 1.0 N B:ASP131 4.4 0.0 1.0 H B:ASP133 4.4 0.0 1.0 CB B:ASP133 4.5 0.0 1.0 HG22 B:ILE130 4.5 0.0 1.0 HB2 B:GLN135 4.6 0.0 1.0 N B:ASP133 4.6 0.0 1.0 C B:GLY134 4.6 0.0 1.0 CA B:ASP133 4.6 0.0 1.0 NE2 B:GLN135 4.6 0.0 1.0 CD B:GLN135 4.7 0.0 1.0 H B:VAL136 4.8 0.0 1.0 CB B:VAL136 4.9 0.0 1.0 HA B:GLN135 4.9 0.0 1.0 CG2 B:ILE130 4.9 0.0 1.0 HB2 B:ASP133 4.9 0.0 1.0 O B:GLY134 5.0 0.0 1.0 N B:GLY134 5.0 0.0 1.0

G.Bernardo-Seisdedos, E.Nunez, C.Gomis, C.Malo, A.Villarroel, O.Millet. Structural Basis and Energy Landscape For the CA2+Gating and Calmodulation of the KV7.2 K+Channel. Proc. Natl. Acad. Sci. V. 115 2395 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29463698
DOI: 10.1073/PNAS.1800235115