Calcium in PDB 6h16: Structure of LRP6 P3E3P4E4 in Complex with Vhh L-P2-D07

The structure of Structure of LRP6 P3E3P4E4 in Complex with Vhh L-P2-D07, PDB code: 6h16 was solved by P.Gros, R.C.Van Scherpenzeel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	82.10 / 2.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	92.795, 105.954, 164.191, 90.00, 90.00, 90.00
R / Rfree (%)	21.1 / 25.2

The binding sites of Calcium atom in the Structure of LRP6 P3E3P4E4 in Complex with Vhh L-P2-D07 (pdb code 6h16). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure of LRP6 P3E3P4E4 in Complex with Vhh L-P2-D07, PDB code: 6h16:

Calcium binding site 1 out of 1 in the Structure of LRP6 P3E3P4E4 in Complex with Vhh L-P2-D07


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of LRP6 P3E3P4E4 in Complex with Vhh L-P2-D07 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1315 b:0.2 occ:1.00 O A:HOH1403 2.5 0.4 1.0 O A:HOH1407 2.6 74.7 1.0 O A:HOH1415 2.7 0.5 1.0 O A:HOH1414 2.7 98.2 1.0 O A:HOH1402 2.9 88.3 1.0 O A:LEU1107 3.2 97.8 1.0 O A:HOH1404 3.2 85.0 1.0 O A:HOH1412 3.8 0.6 1.0 O A:LEU1150 3.9 0.2 1.0 C A:LEU1107 4.4 95.3 1.0 CG2 A:THR1151 4.6 0.8 1.0 O A:ILE1191 4.7 0.8 1.0 CD2 A:HIS1192 4.7 0.8 1.0 CA A:ALA1108 4.9 0.7 1.0

N.Fenderico, R.C.Van Scherpenzeel, M.Goldflam, D.Proverbio, I.Jordens, T.Kralj, S.Stryeck, T.Z.Bass, G.Hermans, C.Ullman, T.Aastrup, P.Gros, M.M.Maurice. Anti-LRP5/6 Vhhs Promote Differentiation of Wnt-Hypersensitive Intestinal Stem Cells. Nat Commun V. 10 365 2019.
ISSN: ESSN 2041-1723
PubMed: 30664649
DOI: 10.1038/S41467-018-08172-Z