Calcium in PDB 6hu9: III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae

All present enzymatic activity of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae:
1.10.2.2; 1.9.3.1;

The structure of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Zinc	(Zn)	2 atoms
Iron	(Fe)	14 atoms
Copper	(Cu)	6 atoms

The binding sites of Calcium atom in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae (pdb code 6hu9). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae, PDB code: 6hu9:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ a:Ca604 b:48.0 occ:1.00 O a:GLU39 2.5 39.2 1.0 O a:ALA42 2.6 38.5 1.0 O a:GLY44 2.8 42.3 1.0 OE1 a:GLU39 3.1 39.2 1.0 O a:PRO441 3.2 35.7 1.0 C a:GLU39 3.7 39.2 1.0 C a:ALA42 3.8 38.5 1.0 C a:GLY44 3.9 42.3 1.0 CD a:GLU39 3.9 39.2 1.0 N a:GLY44 4.1 42.3 1.0 OD1 a:ASP442 4.1 38.5 1.0 CA a:LEU40 4.3 34.0 1.0 OE2 a:GLU39 4.3 39.2 1.0 C a:PRO441 4.3 35.7 1.0 CE2 a:TYR443 4.4 35.8 1.0 C a:PRO43 4.4 39.3 1.0 CA a:PRO43 4.4 39.3 1.0 N a:LEU40 4.4 34.0 1.0 CA a:ASP442 4.5 38.5 1.0 N a:ALA42 4.5 38.5 1.0 N a:PRO43 4.6 39.3 1.0 CA a:GLY44 4.6 42.3 1.0 CG a:GLN46 4.6 45.2 1.0 CG a:ASP442 4.7 38.5 1.0 OH a:TYR443 4.7 35.8 1.0 CA a:GLU39 4.7 39.2 1.0 CD1 a:LEU40 4.7 34.0 1.0 N a:ALA41 4.8 36.6 1.0 CZ a:TYR443 4.8 35.8 1.0 C a:LEU40 4.8 34.0 1.0 N a:SER45 4.8 46.6 1.0 N a:GLN46 4.8 45.2 1.0 CA a:ALA42 4.8 38.5 1.0 N a:ASP442 4.9 38.5 1.0 CB a:ASP442 4.9 38.5 1.0 CA a:SER45 5.0 46.6 1.0 CB a:GLU39 5.0 39.2 1.0

Calcium binding site 2 out of 2 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ m:Ca604 b:56.4 occ:1.00 O m:ALA42 2.6 39.5 1.0 O m:GLU39 2.6 43.0 1.0 O m:GLY44 3.2 47.4 1.0 O m:PRO441 3.4 45.9 1.0 OE1 m:GLU39 3.6 43.0 1.0 C m:ALA42 3.6 39.5 1.0 C m:GLU39 3.8 43.0 1.0 CA m:PRO43 3.9 42.3 1.0 N m:GLY44 4.1 47.4 1.0 CE2 m:TYR443 4.1 41.9 1.0 C m:GLY44 4.1 47.4 1.0 CA m:LEU40 4.1 39.2 1.0 C m:PRO43 4.1 42.3 1.0 OH m:TYR443 4.2 41.9 1.0 N m:PRO43 4.2 42.3 1.0 OD1 m:ASP442 4.3 45.9 1.0 CD1 m:LEU40 4.3 39.2 1.0 CZ m:TYR443 4.3 41.9 1.0 N m:LEU40 4.4 39.2 1.0 CD m:GLU39 4.5 43.0 1.0 N m:ALA42 4.5 39.5 1.0 CA m:ASP442 4.5 45.9 1.0 C m:PRO441 4.5 45.9 1.0 CG m:ASP442 4.6 45.9 1.0 C m:LEU40 4.6 39.2 1.0 CG m:GLN46 4.7 50.2 1.0 N m:ALA41 4.7 36.4 1.0 CA m:GLY44 4.7 47.4 1.0 CA m:ALA42 4.7 39.5 1.0 CD2 m:TYR443 4.8 41.9 1.0 OE2 m:GLU39 4.8 43.0 1.0 CB m:ASP442 4.9 45.9 1.0 O m:PRO43 4.9 42.3 1.0 CA m:GLU39 4.9 43.0 1.0 N m:ASP442 5.0 45.9 1.0

A.M.Hartley, N.Lukoyanova, Y.Zhang, A.Cabrera-Orefice, S.Arnold, B.Meunier, N.Pinotsis, A.Marechal. Structure of Yeast Cytochrome C Oxidase in A Supercomplex with Cytochrome BC1. Nat. Struct. Mol. Biol. V. 26 78 2019.
ISSN: ESSN 1545-9985
PubMed: 30598554
DOI: 10.1038/S41594-018-0172-Z