Calcium »
PDB 6hhz-6i02 »
6hza »
Calcium in PDB 6hza: X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba
Enzymatic activity of X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba
All present enzymatic activity of X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba:
3.4.21.75;
3.4.21.75;
Protein crystallography data
The structure of X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba, PDB code: 6hza
was solved by
S.O.Dahms,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 45.88 / 1.90 |
| Space group | P 65 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 131.371, 131.371, 155.195, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 16.6 / 18.6 |
Other elements in 6hza:
The structure of X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba also contains other interesting chemical elements:
| Chlorine | (Cl) | 1 atom |
| Sodium | (Na) | 3 atoms |
Calcium Binding Sites:
The binding sites of Calcium atom in the X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba
(pdb code 6hza). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba, PDB code: 6hza:
Jump to Calcium binding site number: 1; 2; 3;
In total 3 binding sites of Calcium where determined in the X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba, PDB code: 6hza:
Jump to Calcium binding site number: 1; 2; 3;
Calcium binding site 1 out of 3 in 6hza
Go back to
Calcium Binding Sites List in 6hza
Calcium binding site 1 out
of 3 in the X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba within 5.0Å range:
|
Calcium binding site 2 out of 3 in 6hza
Go back to
Calcium Binding Sites List in 6hza
Calcium binding site 2 out
of 3 in the X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba within 5.0Å range:
|
Calcium binding site 3 out of 3 in 6hza
Go back to
Calcium Binding Sites List in 6hza
Calcium binding site 3 out
of 3 in the X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of X-Ray Structure of Furin in Complex with the Cyclic Peptide C[Glutaryl-Arg-Arg-Lys]-Arg-4-Amba within 5.0Å range:
|
Reference:
T.Van Lam Van,
T.Ivanova,
K.Hardes,
M.R.Heindl,
R.E.Morty,
E.Bottcher-Friebertshauser,
I.Lindberg,
M.E.Than,
S.O.Dahms,
T.Steinmetzer.
Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin. Chemmedchem V. 14 673 2019.
ISSN: ESSN 1860-7187
PubMed: 30680958
DOI: 10.1002/CMDC.201800807
Page generated: Tue Jul 16 08:35:46 2024
ISSN: ESSN 1860-7187
PubMed: 30680958
DOI: 10.1002/CMDC.201800807
Last articles
Zn in 9JPJZn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
