Calcium in PDB 6iqq: Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi

All present enzymatic activity of Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi:
3.4.21.102;

The structure of Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi, PDB code: 6iqq was solved by C.K.Chueh, C.I.Chang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.98 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	118.936, 143.882, 153.599, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 27.8

The binding sites of Calcium atom in the Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi (pdb code 6iqq). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi, PDB code: 6iqq:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca701 b:58.5 occ:1.00 O C:GLY408 2.4 53.0 1.0 O C:GLN435 2.4 57.6 1.0 OD2 C:ASP431 2.4 32.9 1.0 OD1 C:ASP433 2.4 43.6 1.0 O C:PRO412 2.6 44.8 1.0 O C:ILE411 2.6 52.0 1.0 O C:ASP433 3.1 0.7 1.0 CG C:ASP431 3.3 39.2 1.0 C C:PRO412 3.5 52.4 1.0 C C:GLN435 3.5 51.0 1.0 C C:GLY408 3.5 43.8 1.0 OD1 C:ASP431 3.5 41.5 1.0 CG C:ASP433 3.7 55.4 1.0 N C:GLN435 3.7 43.8 1.0 C C:ILE411 3.8 56.5 1.0 CA C:PRO412 4.1 56.5 1.0 CA C:GLN435 4.1 51.0 1.0 CA C:GLY408 4.2 43.0 1.0 C C:ASP433 4.2 67.7 1.0 OD2 C:ASP433 4.3 46.4 1.0 N C:PRO412 4.4 60.4 1.0 N C:ALA413 4.5 43.4 1.0 CB C:GLN435 4.5 45.4 1.0 N C:LEU409 4.6 44.6 1.0 C C:GLY434 4.6 53.2 1.0 N C:VAL436 4.7 47.3 1.0 CB C:ASP431 4.7 37.1 1.0 CA C:LEU409 4.8 40.5 1.0 CB C:ASP433 4.8 59.7 1.0 CA C:ALA413 4.8 44.0 1.0 CA C:ASP433 5.0 59.3 1.0 N C:GLY434 5.0 60.5 1.0 N C:ILE411 5.0 46.6 1.0 CA C:GLY434 5.0 58.3 1.0 CA C:ILE411 5.0 53.4 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Prc with S452I and L252Y Mutations in Complex with Nlpi within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca701 b:48.1 occ:1.00 O D:GLY408 2.3 50.9 1.0 OD1 D:ASP433 2.4 34.8 1.0 OD2 D:ASP431 2.4 32.4 1.0 O D:GLN435 2.4 49.7 1.0 O D:PRO412 2.5 35.1 1.0 O D:ILE411 2.6 32.8 1.0 O D:ASP433 3.1 92.9 1.0 CG D:ASP431 3.3 36.1 1.0 C D:PRO412 3.4 42.2 1.0 C D:GLY408 3.5 42.0 1.0 OD1 D:ASP431 3.6 36.3 1.0 C D:GLN435 3.6 46.5 1.0 CG D:ASP433 3.7 46.7 1.0 N D:GLN435 3.8 40.9 1.0 C D:ILE411 3.8 40.4 1.0 CA D:PRO412 4.1 44.5 1.0 CA D:GLN435 4.1 44.1 1.0 CA D:GLY408 4.1 38.0 1.0 C D:ASP433 4.1 64.3 1.0 OD2 D:ASP433 4.3 41.0 1.0 N D:ALA413 4.4 41.9 1.0 N D:PRO412 4.4 42.9 1.0 CB D:GLN435 4.5 46.9 1.0 N D:LEU409 4.6 39.1 1.0 C D:GLY434 4.6 49.3 1.0 CB D:ASP431 4.7 36.3 1.0 N D:VAL436 4.7 48.8 1.0 CA D:LEU409 4.8 35.4 1.0 CA D:ALA413 4.8 38.6 1.0 CB D:ASP433 4.8 45.7 1.0 CA D:ASP433 4.9 51.5 1.0 N D:ILE411 5.0 39.6 1.0 N D:GLY434 5.0 57.4 1.0 CA D:GLY434 5.0 54.0 1.0 CA D:ILE411 5.0 41.1 1.0 C D:LEU409 5.0 37.7 1.0

C.K.Chueh, N.Som, L.C.Ke, M.R.Ho, M.Reddy, C.I.Chang. Structural Basis For the Differential Regulatory Roles of the Pdz Domain in C-Terminal Processing Proteases. Mbio V. 10 2019.
ISSN: ESSN 2150-7511
PubMed: 31387902
DOI: 10.1128/MBIO.01129-19