Calcium in PDB 6jfm: MITOFUSIN2 (MFN2)_T111D

The structure of MITOFUSIN2 (MFN2)_T111D, PDB code: 6jfm was solved by Y.J.Li, Y.L.Cao, J.X.Feng, Y.B.Qi, S.X.Meng, J.F.Yang, Y.T.Zhong, S.S.Kang, X.X.Chen, L.Lan, L.Luo, B.Yu, S.D.Chen, D.C.Chan, J.J.Hu, S.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.64 / 2.09
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.437, 126.563, 79.972, 90.00, 102.46, 90.00
R / Rfree (%)	17.6 / 22.9

The binding sites of Calcium atom in the MITOFUSIN2 (MFN2)_T111D (pdb code 6jfm). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the MITOFUSIN2 (MFN2)_T111D, PDB code: 6jfm:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the MITOFUSIN2 (MFN2)_T111D


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of MITOFUSIN2 (MFN2)_T111D within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca903 b:93.0 occ:1.00 O B:HOH1010 2.5 55.8 1.0 OE2 B:GLU268 2.6 54.2 1.0 OE2 A:GLU391 2.9 58.0 1.0 OE1 A:GLU391 3.4 58.5 1.0 CD A:GLU391 3.5 53.1 1.0 CD B:GLU268 3.8 50.6 1.0 NH1 A:ARG384 3.9 78.1 1.0 NH2 A:ARG384 4.0 84.5 1.0 OE1 B:GLU268 4.3 51.2 1.0 CZ A:ARG384 4.5 77.0 1.0 CG A:GLU391 4.9 49.1 1.0 CG B:GLU268 5.0 38.9 1.0

Calcium binding site 2 out of 3 in the MITOFUSIN2 (MFN2)_T111D


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of MITOFUSIN2 (MFN2)_T111D within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca904 b:55.9 occ:1.00 O A:HOH1029 2.4 57.4 1.0 OE1 A:GLU73 2.4 69.1 1.0 OD1 A:ASP77 2.5 55.9 1.0 OD2 A:ASP77 2.5 52.8 1.0 CG A:ASP77 2.8 42.7 1.0 OXT A:ACT902 2.9 53.7 1.0 O A:HOH1082 3.1 54.2 1.0 CD A:GLU73 3.3 60.3 1.0 C A:ACT902 3.5 56.7 1.0 CG A:GLU73 3.6 53.6 1.0 O A:ACT902 3.8 53.3 1.0 CB A:ASP77 4.3 38.6 1.0 OE2 A:GLU73 4.4 63.9 1.0 CH3 A:ACT902 4.7 41.6 1.0 O A:GLU73 4.8 36.5 1.0

Calcium binding site 3 out of 3 in the MITOFUSIN2 (MFN2)_T111D


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of MITOFUSIN2 (MFN2)_T111D within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca801 b:88.7 occ:1.00 OD2 B:ASP77 2.5 53.8 1.0 O B:HOH906 2.5 53.4 1.0 OE1 B:GLU73 2.9 64.4 1.0 CG B:ASP77 3.3 46.6 1.0 OD1 B:ASP77 3.5 49.9 1.0 CD B:GLU73 4.0 61.9 1.0 CG B:GLU73 4.5 48.7 1.0 CB B:ASP77 4.7 36.5 1.0 O B:HOH1020 4.8 49.4 1.0 OE2 B:GLU73 5.0 69.7 1.0

Y.J.Li, Y.L.Cao, J.X.Feng, Y.Qi, S.Meng, J.F.Yang, Y.T.Zhong, S.Kang, X.Chen, L.Lan, L.Luo, B.Yu, S.Chen, D.C.Chan, J.Hu, S.Gao. Structural Insights of Human Mitofusin-2 Into Mitochondrial Fusion and CMT2A Onset. Nat Commun V. 10 4914 2019.
ISSN: ESSN 2041-1723
PubMed: 31664033
DOI: 10.1038/S41467-019-12912-0