Calcium in PDB 6jpb: Rabbit CAV1.1-Diltiazem Complex

The binding sites of Calcium atom in the Rabbit CAV1.1-Diltiazem Complex (pdb code 6jpb). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Rabbit CAV1.1-Diltiazem Complex, PDB code: 6jpb:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Rabbit CAV1.1-Diltiazem Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Rabbit CAV1.1-Diltiazem Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1902 b:54.0 occ:1.00 CA A:CA1903 2.1 71.8 1.0 OE1 A:GLU292 2.5 38.2 1.0 OE1 A:GLU614 2.6 37.9 1.0 OE1 A:GLU1014 2.6 27.6 1.0 OE2 A:GLU292 2.8 38.2 1.0 OE2 A:GLU1014 2.9 27.6 1.0 CD A:GLU292 3.0 38.2 1.0 CD A:GLU1014 3.1 27.6 1.0 O A:GLY1322 3.5 55.7 1.0 CD A:GLU614 3.6 37.9 1.0 O A:GLU1323 3.8 35.7 1.0 OE2 A:GLU614 4.0 37.9 1.0 O A:PHE1013 4.4 31.6 1.0 CG A:GLU1014 4.5 27.6 1.0 CG A:GLU292 4.5 38.2 1.0 C A:GLU1323 4.6 35.7 1.0 C A:GLY1322 4.6 55.7 1.0 CA A:GLU1323 4.6 35.7 1.0 CA A:GLU1014 4.8 27.6 1.0 CA A:GLU614 4.8 37.9 1.0 CG A:GLU614 4.9 37.9 1.0 N A:ASP615 4.9 27.8 1.0 CB A:GLU1014 5.0 27.6 1.0

Calcium binding site 2 out of 3 in the Rabbit CAV1.1-Diltiazem Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Rabbit CAV1.1-Diltiazem Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1903 b:71.8 occ:1.00 CA A:CA1902 2.1 54.0 1.0 OE2 A:GLU1014 2.5 27.6 1.0 OE1 A:GLU292 2.5 38.2 1.0 OE1 A:GLU614 3.3 37.9 1.0 CD A:GLU1014 3.5 27.6 1.0 CD A:GLU292 3.6 38.2 1.0 O A:GLY1322 3.7 55.7 1.0 OE1 A:GLU1014 3.7 27.6 1.0 O A:PHE1013 4.0 31.6 1.0 OE2 A:GLU292 4.1 38.2 1.0 CD A:GLU614 4.5 37.9 1.0 CA A:GLU614 4.5 37.9 1.0 O A:MET291 4.7 28.3 1.0 CG A:GLU1014 4.8 27.6 1.0 CB A:GLU614 4.8 37.9 1.0 C A:PHE1013 4.9 31.6 1.0 CG A:GLU292 4.9 38.2 1.0 C A:GLY1322 4.9 55.7 1.0 O A:GLY613 4.9 55.7 1.0

Calcium binding site 3 out of 3 in the Rabbit CAV1.1-Diltiazem Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Rabbit CAV1.1-Diltiazem Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca1101 b:27.1 occ:1.00 OG1 F:THR333 2.3 46.4 1.0 OG F:SER263 2.5 43.0 1.0 OG F:SER265 2.5 42.0 1.0 CB F:SER263 3.4 43.0 1.0 CB F:THR333 3.6 46.4 1.0 OD2 A:ASP78 3.6 35.2 1.0 CB F:SER265 3.8 42.0 1.0 CG2 F:THR333 3.9 46.4 1.0 OD1 A:ASP78 3.9 35.2 1.0 OD2 F:ASP261 3.9 38.4 1.0 CG A:ASP78 4.1 35.2 1.0 OD1 F:ASP365 4.3 46.9 1.0 OD1 F:ASP261 4.5 38.4 1.0 N F:SER265 4.6 42.0 1.0 CG F:ASP261 4.6 38.4 1.0 O F:GLY366 4.6 51.8 1.0 CA F:SER263 4.7 43.0 1.0 CA F:THR333 4.7 46.4 1.0 CA F:SER265 4.8 42.0 1.0 N F:THR333 4.9 46.4 1.0 C F:SER263 4.9 43.0 1.0

Y.Zhao, G.Huang, J.Wu, Q.Wu, S.Gao, Z.Yan, J.Lei, N.Yan. Molecular Basis For Ligand Modulation of A Mammalian Voltage-Gated CA2+Channel. Cell V. 177 1495 2019.
ISSN: ISSN 1097-4172
PubMed: 31150622
DOI: 10.1016/J.CELL.2019.04.043